社区
首页
集团介绍
社区
资讯
行情
学堂
TigerAI
登录
注册
uniQure N.V.(QURE)
17.56
-0.70
-3.83%
行情数据延迟15分钟
社区
社区
资讯
资讯
资料
资料
公告
公告
最新
推荐
Sumire_9572
·
03-07
$uniQure N.V.(QURE)$
继续沽空！！！18-
$uniQure N.V.(QURE)$ 继续沽空！！！18-
回复
评论
点赞
点赞
编组 21备份 2
分享
举报
Sumire_9572
·
03-07
$uniQure N.V.(QURE)$
跳水开始了，，，，
$uniQure N.V.(QURE)$ 跳水开始了，，，，
回复
评论
点赞
点赞
编组 21备份 2
分享
举报
佛系少年cc
·
03-04
$uniQure N.V.(QURE)$
9块以下开始建仓！
$uniQure N.V.(QURE)$ 9块以下开始建仓！
回复
评论
点赞
1
编组 21备份 2
分享
举报
佛系少年cc
·
2025-11-05
$uniQure N.V.(QURE)$
你是🐶？每天都盘前大跌，半夜拉起来，老子跑都没法跑
$uniQure N.V.(QURE)$ 你是🐶？每天都盘前大跌，半夜拉起来，老子跑都没法跑
回复
评论
点赞
2
编组 21备份 2
分享
举报
期权不隔夜
·
2025-10-10
$QURE 20251017 60.0 CALL$
加油
$QURE 20251017 60.0 CALL$ 加油
回复
评论
点赞
点赞
编组 21备份 2
分享
举报
搜山捡海
·
2025-09-29
$uniQure N.V.(QURE)$
大单再跑路还有人进真的是不要钱了。这几天长得太猛了，看着吓人！！！
$uniQure N.V.(QURE)$ 大单再跑路还有人进真的是不要钱了。这几天长得太猛了，看着吓人！！！
回复
评论
点赞
1
编组 21备份 2
分享
举报
zeroxu666
·
2025-04-17
$uniQure N.V.(QURE)$
有重大突破的孤儿药
$uniQure N.V.(QURE)$ 有重大突破的孤儿药
回复
评论
点赞
2
编组 21备份 2
分享
举报
NI500
·
2024-12-17
12天暴涨152%，这只基因治疗股票是否值得持有至2025年？
近期，国际基因治疗开发商uniQure（NASDAQ: QURE）的股价大幅上涨，投资者纷纷将目光投向这家因FDA（美国食品药品监督管理局）审批消息以及亨廷顿病新药研发而备受关注的公司。在12月的前12天内，该公司股票价格飙升了152%。此时，市场想知道这只股票是否还能继续攀升并在2025年创造更高收益。以下是推动这只基因治疗股票价格上涨的利好与公司面临的潜在挑战的综合分析。uniQure股票为何暴涨？12月10日，uniQure宣布了一则关于其候选基因治疗药物AMT-130的利好消息，引发了市场的广泛关注。AMT-130是一款用于治疗亨廷顿病的实验性基因疗法。根据uniQure的声明，FDA已表示愿意基于现有的第一期/第二期临床试验结果来审查该药物的加速审批申请。这对亨廷顿病患者来说可能是一个重大突破，因为该病症发展速度较慢，而FDA认可的临床试验自2019年开始，预计至2029年才能完成。如果这款药物能提前进入市场，将有助于填补这一领域当前缺乏有效治疗的现状。需要保持谨慎的原因尽管该公告令人鼓舞，但市场仍需保持一份理性。FDA尚未正式审查AMT-130的加速审批申请，仅表示将在2025年上半年与uniQure召开会议，届时或许会进一步明确潜在的审批路径。此外，现有的第一期/第二期试验设计也存在一些限制。试验中包含一组接受“假手术”的对照组，但允许这些患者在12个月后注射AMT-130。然而，由于亨廷顿病的病情恶化通常需要更长时间，这12个月的观察期可能不足以得到显著的对比结果。基因疗法的市场挑战即使AMT-130获得FDA批准，uniQure仍需面对实施和推广基因疗法的市场挑战。基因疗法往往价格昂贵，消费者接受度较低。以uniQure首款获批的基因疗法Hemgenix为例：该药物2022年获得批准治疗B型血友病，定价达350万美元。然而，数据显示，uniQure 202
12天暴涨152%，这只基因治疗股票是否值得持有至2025年？
回复
评论
点赞
点赞
编组 21备份 2
分享
举报
牛唐
·
2024-08-26
股价两天暴涨168%，这家基因疗法企业为何反转？
7月9日，美股上市的基因疗法公司uniQure(NASDAQ:QURE)发布了AMT-130在治疗亨廷顿病的美国和欧洲I/II期临床试验积极中期数据，股价当日暴涨76.46%，随即在第二日再度暴涨51.72%，股价在两个交易日内累计涨幅167.72%。 而在2023年下半年，uniQure仍在大幅裁员，暂停并卖掉部分药物管线，同年的股价跌幅高达70.14%，一家陷入困境的药企为何在短期内重获资本市场的青睐？ 图片 专注于基因疗法的创新药企 Uniqure于1998年在荷兰的阿姆斯特丹成立，并于2014年5月在美国纳斯达克交易所上市，是一家致力为罕见病开发基因疗法的企业，第一个上市的基因疗法Glybera就是由Uniqure开发。 技术方面，Uniqure的基因疗法不但能表达缺失或者低表达的蛋白，而且也能沉默疾病基因。同时，公司的AAV5载体具有很好的免疫原性，几乎在所有观察到的抗AAV5抗体浓度中，对AAV5基因治疗的转导效率没有任何影响。 图片 适应症方面，Uniqure主要选择尚未有药物获批或现有疗法存在缺陷的罕见病，如血友病，亨廷顿病（Huntington Disease）、难治性颞叶癫痫（rTLE）、法布里病、肌萎缩侧索硬化症等。 2012年，uniQure的药物Glybera获得了欧盟药物管理机构批准，成为首个获批上市的基因疗法，该药物利用AAV载体将一个功能性脂蛋白脂肪酶（LPL）基因递送至骨骼肌，用于治疗脂蛋白脂肪酶缺乏症（LPLD）。 Glybera的上市奠定了uniQure在基因治疗领域的领导者地位，也吸引了大药企的合作。2015年，公司与百时美施贵宝与签署了一份高达10亿美元的独家合作协议，双方合作开发基因疗法用于心血管疾病领域多达10个靶标，BMS随后还入股uniQure，持股比例达9.9%。 不过Glyber的商业化不顺利，因误诊率高、市场需求少等原
股价两天暴涨168%，这家基因疗法企业为何反转？
回复
评论
点赞
点赞
编组 21备份 2
分享
举报
加载更多
公司概况
公司名称
uniQure N.V.
所属市场
NASDAQ
成立日期
- -
员工人数
- -
办公地址
- -
公司网址
http://www.uniqure.com
邮政编码
- -
联系电话
- -
联系传真
- -
公司概况
uniQure N.V.作为私人有限责任公司于2012年1月9日依照荷兰相关法律条文成立。公司是一家专业从事基因治疗的生物技术企业，致力于为罕见病和重病患者开发单一治疗途径。其管线包括针对亨廷顿病、与SOD1突变相关的肌萎缩性侧索硬化症、难治性中位颞叶癫痫和法布里病的临床候选药物，反映了对推进基因治疗领域创新疗法的关注。
03-05
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
03-04
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
03-04
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
03-02
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
03-02
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
03-02
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
03-02
年度报告
Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]
Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]
03-02
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
02-25
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
02-25
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
01-13
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
01-12
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
01-09
关联方拟减持公告
Form 144 - Report of proposed sale of securities
Form 144 - Report of proposed sale of securities
01-09
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
2025-12-04
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
分时
5日
日
周
月
数据加载中...
最高
18.98
今开
18.51
量比
0.29
最低
17.53
昨收
18.26
换手率
7.15%
热议股票
{"pagemeta":{"title":"uniQure N.V.(QURE)_个股概要_股票价格_最新资讯_行情走势_历史数据","description":"美港股上老虎。老虎社区提供uniQure N.V.(QURE)今日价格,行情走势,历史数据,股票概要及实时的新闻资讯,近期大事等重要参考决策数据。","keywords":"uniQure N.V.,QURE,uniQure N.V.股票,uniQure N.V.股票老虎,uniQure N.V.股票老虎国际,uniQure N.V.行情,uniQure N.V.股票行情,uniQure N.V.股价,uniQure N.V.股市,uniQure N.V.股票价格,uniQure N.V.股票交易,uniQure N.V.股票购买,uniQure N.V.股票实时行情,购买美股,购买港股,港股开户,美股开户,美股交易,港股交易,开通美港股账户,老虎国际行情","social":{"og_title":"uniQure N.V.(QURE)_个股概要_股票价格_最新资讯_行情走势_历史数据","og_description":"美港股上老虎。老虎社区提供uniQure N.V.(QURE)今日价格,行情走势,历史数据,股票概要及实时的新闻资讯,近期大事等重要参考决策数据。","og_image":"https://static.tigerbbs.com/a0b84b8debbbce3b4440f7fdd5eed2e7"}},"tab":"community","symbol":"QURE","data":{"stockData":{"symbol":"QURE","market":"US","secType":"STK","nameCN":"uniQure N.V.","latestPrice":17.56,"timestamp":1773259200000,"preClose":18.26,"halted":0,"volume":2906647,"delay":0,"changeRate":-0.03833515881708668,"floatShares":40636300,"shares":62291663,"eps":-3.46024,"marketStatus":"盘前交易","change":-0.7,"latestTime":"03-12 04:27:13 EDT","open":18.51,"high":18.98,"low":17.53,"amount":52370372.803444,"amplitude":0.079409,"askPrice":18.49,"askSize":39,"bidPrice":17.13,"bidSize":39,"shortable":3,"etf":0,"ttmEps":-3.46024,"tradingStatus":1,"nextMarketStatus":{"tag":"开盘","tradingStatus":2,"beginTime":1773322200000},"marketStatusCode":1,"adr":0,"adrRate":0,"listingDate":1391576400000,"exchange":"NASDAQ","adjPreClose":17.56,"postHourTrading":{"tag":"盘后","latestPrice":17.68,"preClose":17.56,"latestTime":"19:58 EDT","volume":29814,"amount":524095.7204,"timestamp":1773273533986,"change":0.12,"changeRate":0.006834,"amplitude":0.017654},"volumeRatio":0.2923170755002872,"impliedVol":1.5786,"impliedVolPercentile":0.804},"tweetData":{"bottom":false,"list":[{"cardType":"TWEET","cardId":"TWEET.539949918122688","cardData":[{"tweetId":"539949918122688","author":{"authorId":"3514369206910047","idStr":"3514369206910047","name":"Sumire_9572","avatar":"https://static.tigerbbs.com/5e7fbf0b7a1ee37b79a360eb47696d4b","userType":1,"introduction":"","crmLevel":9,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":73,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"title":"","digest":"<a href=\"https://laohu8.com/S/QURE\">$uniQure N.V.(QURE)$ </a> 继续沽空！！！18-","plainDigest":"$uniQure N.V.(QURE)$ 继续沽空！！！18-","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1772841846698,"gmtModify":1772841848868,"symbols":["QURE"],"themeIds":[],"popularizeThemeFlag":false,"imageCount":0,"images":[],"repostCount":0,"viewCount":47,"likeCount":0,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":false,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/539949918122688","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":[],"commentAndTweetFlag":false,"upFlag":false,"length":33,"displayRows":4,"foldSize":0,"authorId":"3514369206910047"}],"position":0},{"cardType":"TWEET","cardId":"TWEET.539946214732880","cardData":[{"tweetId":"539946214732880","author":{"authorId":"3514369206910047","idStr":"3514369206910047","name":"Sumire_9572","avatar":"https://static.tigerbbs.com/5e7fbf0b7a1ee37b79a360eb47696d4b","userType":1,"introduction":"","crmLevel":9,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":73,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"title":"","digest":"<a href=\"https://laohu8.com/S/QURE\">$uniQure N.V.(QURE)$ </a> 跳水开始了，，，，","plainDigest":"$uniQure N.V.(QURE)$ 跳水开始了，，，，","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1772840877214,"gmtModify":1772840878946,"symbols":["QURE"],"themeIds":[],"popularizeThemeFlag":false,"imageCount":0,"images":[],"repostCount":0,"viewCount":69,"likeCount":0,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":false,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/539946214732880","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":[],"commentAndTweetFlag":false,"upFlag":false,"length":33,"displayRows":4,"foldSize":0,"authorId":"3514369206910047"}],"position":0},{"cardType":"TWEET","cardId":"TWEET.538985506336816","cardData":[{"tweetId":"538985506336816","author":{"authorId":"3498777212274767","idStr":"3498777212274767","name":"佛系少年cc","avatar":"https://static.tigerbbs.com/c9b99bb4c4b228ba142fb302b4066f8e","userType":1,"introduction":"","crmLevel":4,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":2,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"title":"","digest":"<a href=\"https://laohu8.com/S/QURE\">$uniQure N.V.(QURE)$</a> 9块以下开始建仓！","plainDigest":"$uniQure N.V.(QURE)$ 9块以下开始建仓！","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1772609227375,"gmtModify":1772609229684,"symbols":["QURE"],"themeIds":[],"popularizeThemeFlag":false,"imageCount":0,"images":[],"repostCount":0,"viewCount":126,"likeCount":1,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":false,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/538985506336816","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":[],"commentAndTweetFlag":false,"upFlag":false,"length":35,"displayRows":4,"foldSize":0,"authorId":"3498777212274767"}],"position":0},{"cardType":"TWEET","cardId":"TWEET.496889667072144","cardData":[{"tweetId":"496889667072144","author":{"authorId":"3498777212274767","idStr":"3498777212274767","name":"佛系少年cc","avatar":"https://static.tigerbbs.com/c9b99bb4c4b228ba142fb302b4066f8e","userType":1,"introduction":"","crmLevel":4,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":2,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"title":"","digest":"<a href=\"https://laohu8.com/S/QURE\">$uniQure N.V.(QURE)$</a> 你是🐶？每天都盘前大跌，半夜拉起来，老子跑都没法跑","plainDigest":"$uniQure N.V.(QURE)$ 你是🐶？每天都盘前大跌，半夜拉起来，老子跑都没法跑","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1762333557636,"gmtModify":1762334230624,"symbols":["QURE"],"themeIds":[],"popularizeThemeFlag":false,"imageCount":0,"images":[],"repostCount":0,"viewCount":992,"likeCount":2,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":false,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/496889667072144","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":[],"commentAndTweetFlag":false,"upFlag":false,"length":66,"displayRows":4,"foldSize":0,"authorId":"3498777212274767"}],"position":0},{"cardType":"TWEET","cardId":"TWEET.487418523685752","cardData":[{"tweetId":"487418523685752","author":{"authorId":"3445990815937032","idStr":"3445990815937032","name":"期权不隔夜","avatar":"https://static.tigerbbs.com/3027d52a93306f14ba4547a864966111","userType":1,"introduction":"","crmLevel":6,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":196,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"digest":"<a href=\"https://laohu8.com/OPT/QURE 20251017 60.0 CALL\">$QURE 20251017 60.0 CALL$ </a> 加油","plainDigest":"$QURE 20251017 60.0 CALL$ 加油","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1760027613751,"gmtModify":1760027625519,"symbols":["QURE"],"themeIds":["5bfad02ab61749c8bfe6573ac7bbe8a3"],"popularizeThemeFlag":false,"imageCount":1,"images":[{"url":"https://static.tigerbbs.com/efcc62efcf32908a0d6b5dc67b5b579f","width":"882","height":"1668"}],"repostCount":0,"viewCount":567,"likeCount":0,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":false,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/487418523685752","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":["晒单贴"],"commentAndTweetFlag":false,"upFlag":false,"length":26,"displayRows":4,"foldSize":0,"authorId":"3445990815937032"}],"position":0},{"cardType":"TWEET","cardId":"TWEET.483843181432832","cardData":[{"tweetId":"483843181432832","author":{"authorId":"3453198934663129","idStr":"3453198934663129","name":"搜山捡海","avatar":"https://static.laohu8.com/default-avatar.jpg","userType":1,"introduction":"","userGiftHeadFrame":"https://static.tigerbbs.com/b073a07f77dbe6b3bec6b12311fde6bd","crmLevel":6,"crmLevelSwitch":1,"wearingBadge":{"badgeId":"e50ce593bb40487ebfb542ca54f6a561-4","templateUuid":"e50ce593bb40487ebfb542ca54f6a561","name":"Tiger Star","description":"Join the tiger community for 2000 days","bigImgUrl":"https://static.tigerbbs.com/dddf24b906c7011de2617d4fb3f76987","smallImgUrl":"https://static.tigerbbs.com/53d58ad32c97254c6f74db8b97e6ec49","grayImgUrl":"https://static.tigerbbs.com/6304700d92ad91c7a33e2e92ec32ecc1","redirectLinkEnabled":0,"hasAllocated":1,"isWearing":1,"stampPosition":0,"hasStamp":0,"allocationCount":1,"allocatedDate":"2022.09.12","individualDisplayEnabled":0,"individualDisplaySort":0},"individualDisplayBadges":[],"fanSize":56,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"digest":"<a href=\"https://laohu8.com/S/QURE\">$uniQure N.V.(QURE)$ </a>大单再跑路还有人进真的是不要钱了。这几天长得太猛了，看着吓人！！！","plainDigest":"$uniQure N.V.(QURE)$ 大单再跑路还有人进真的是不要钱了。这几天长得太猛了，看着吓人！！！","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1759154968430,"gmtModify":1759154970395,"symbols":["QURE"],"themeIds":[],"popularizeThemeFlag":false,"imageCount":0,"images":[],"repostCount":0,"viewCount":1370,"likeCount":1,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":false,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/483843181432832","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":[],"commentAndTweetFlag":false,"upFlag":false,"length":82,"displayRows":4,"foldSize":0,"authorId":"3453198934663129"}],"position":0},{"cardType":"TWEET","cardId":"TWEET.425525991546952","cardData":[{"tweetId":"425525991546952","author":{"authorId":"3544572238091832","idStr":"3544572238091832","name":"zeroxu666","avatar":"https://static.laohu8.com/default-avatar.jpg","userType":1,"introduction":"","userGiftHeadFrame":"https://static.tigerbbs.com/0a8758340a08196056f8bc1e54805193","crmLevel":5,"crmLevelSwitch":0,"wearingBadge":{"badgeId":"35ec162348d5460f88c959321e554969-3","templateUuid":"35ec162348d5460f88c959321e554969","name":"Legendary Trader","description":"Total number of securities or futures transactions reached 300","bigImgUrl":"https://static.tigerbbs.com/656db16598a0b8f21429e10d6c1cb033","smallImgUrl":"https://static.tigerbbs.com/03f10910d4dd9234f9b5702a3342193a","grayImgUrl":"https://static.tigerbbs.com/0c767e35268feb729d50d3fa9a386c5a","redirectLinkEnabled":0,"hasAllocated":1,"isWearing":1,"stampPosition":0,"hasStamp":0,"allocationCount":1,"allocatedDate":"2021.12.21","exceedPercentage":"93.27%","individualDisplayEnabled":0,"individualDisplaySort":0},"individualDisplayBadges":[],"fanSize":69,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"digest":"<a href=\"https://laohu8.com/S/QURE\">$uniQure N.V.(QURE)$</a> 有重大突破的孤儿药","plainDigest":"$uniQure N.V.(QURE)$ 有重大突破的孤儿药","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1744897973972,"gmtModify":1744898136163,"symbols":["QURE"],"themeIds":[],"popularizeThemeFlag":false,"imageCount":0,"images":[],"repostCount":0,"viewCount":1836,"likeCount":2,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":false,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/425525991546952","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":[],"commentAndTweetFlag":false,"upFlag":false,"length":37,"displayRows":4,"foldSize":0,"authorId":"3544572238091832"}],"position":0},{"cardType":"TWEET","cardId":"TWEET.382713362464816","cardData":[{"tweetId":"382713362464816","author":{"authorId":"9000000000000036","idStr":"9000000000000036","name":"NI500","avatar":"https://static.laohu8.com/default-avatar.jpg","userType":8,"introduction":"","crmLevel":1,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":483,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"title":"12天暴涨152%，这只基因治疗股票是否值得持有至2025年？","digest":"近期，国际基因治疗开发商uniQure（NASDAQ: QURE）的股价大幅上涨，投资者纷纷将目光投向这家因FDA（美国食品药品监督管理局）审批消息以及亨廷顿病新药研发而备受关注的公司。在12月的前12天内，该公司股票价格飙升了152%。此时，市场想知道这只股票是否还能继续攀升并在2025年创造更高收益。以下是推动这只基因治疗股票价格上涨的利好与公司面临的潜在挑战的综合分析。uniQure股票为何暴涨？12月10日，uniQure宣布了一则关于其候选基因治疗药物AMT-130的利好消息，引发了市场的广泛关注。AMT-130是一款用于治疗亨廷顿病的实验性基因疗法。根据uniQure的声明，FDA已表示愿意基于现有的第一期/第二期临床试验结果来审查该药物的加速审批申请。这对亨廷顿病患者来说可能是一个重大突破，因为该病症发展速度较慢，而FDA认可的临床试验自2019年开始，预计至2029年才能完成。如果这款药物能提前进入市场，将有助于填补这一领域当前缺乏有效治疗的现状。需要保持谨慎的原因尽管该公告令人鼓舞，但市场仍需保持一份理性。FDA尚未正式审查AMT-130的加速审批申请，仅表示将在2025年上半年与uniQure召开会议，届时或许会进一步明确潜在的审批路径。此外，现有的第一期/第二期试验设计也存在一些限制。试验中包含一组接受“假手术”的对照组，但允许这些患者在12个月后注射AMT-130。然而，由于亨廷顿病的病情恶化通常需要更长时间，这12个月的观察期可能不足以得到显著的对比结果。基因疗法的市场挑战即使AMT-130获得FDA批准，uniQure仍需面对实施和推广基因疗法的市场挑战。基因疗法往往价格昂贵，消费者接受度较低。以uniQure首款获批的基因疗法Hemgenix为例：该药物2022年获得批准治疗B型血友病，定价达350万美元。然而，数据显示，uniQure 202","plainDigest":"近期，国际基因治疗开发商uniQure（NASDAQ: QURE）的股价大幅上涨，投资者纷纷将目光投向这家因FDA（美国食品药品监督管理局）审批消息以及亨廷顿病新药研发而备受关注的公司。在12月的前12天内，该公司股票价格飙升了152%。此时，市场想知道这只股票是否还能继续攀升并在2025年创造更高收益。以下是推动这只基因治疗股票价格上涨的利好与公司面临的潜在挑战的综合分析。uniQure股票为何暴涨？12月10日，uniQure宣布了一则关于其候选基因治疗药物AMT-130的利好消息，引发了市场的广泛关注。AMT-130是一款用于治疗亨廷顿病的实验性基因疗法。根据uniQure的声明，FDA已表示愿意基于现有的第一期/第二期临床试验结果来审查该药物的加速审批申请。这对亨廷顿病患者来说可能是一个重大突破，因为该病症发展速度较慢，而FDA认可的临床试验自2019年开始，预计至2029年才能完成。如果这款药物能提前进入市场，将有助于填补这一领域当前缺乏有效治疗的现状。需要保持谨慎的原因尽管该公告令人鼓舞，但市场仍需保持一份理性。FDA尚未正式审查AMT-130的加速审批申请，仅表示将在2025年上半年与uniQure召开会议，届时或许会进一步明确潜在的审批路径。此外，现有的第一期/第二期试验设计也存在一些限制。试验中包含一组接受“假手术”的对照组，但允许这些患者在12个月后注射AMT-130。然而，由于亨廷顿病的病情恶化通常需要更长时间，这12个月的观察期可能不足以得到显著的对比结果。基因疗法的市场挑战即使AMT-130获得FDA批准，uniQure仍需面对实施和推广基因疗法的市场挑战。基因疗法往往价格昂贵，消费者接受度较低。以uniQure首款获批的基因疗法Hemgenix为例：该药物2022年获得批准治疗B型血友病，定价达350万美元。然而，数据显示，uniQure 202","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1734394560000,"gmtModify":1734491705276,"symbols":["QURE","WRD","PHH"],"themeIds":[],"popularizeThemeFlag":false,"imageCount":1,"images":[{"url":"https://static.tigerbbs.com/1107e09f33a84d1fb6ecf87a02d5bcd4"}],"repostCount":0,"viewCount":7304,"likeCount":0,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":true,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/382713362464816","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":[],"commentAndTweetFlag":false,"upFlag":true,"length":2418,"displayRows":4,"foldSize":0,"authorId":"9000000000000036"}],"position":0},{"cardType":"TWEET","cardId":"TWEET.342467076857944","cardData":[{"tweetId":"342467076857944","author":{"authorId":"3452938437060827","idStr":"3452938437060827","name":"牛唐","avatar":"https://static.tigerbbs.com/de2e2f2e2676bc8463b050f4e3ff17d2","userType":1,"introduction":"","crmLevel":1,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":6599,"starInvestorFlag":false,"userFollowAuthorFlag":false,"authorFollowUserFlag":false},"userFollowAuthorFlag":false,"authorFollowUserFlag":false,"title":"股价两天暴涨168%，这家基因疗法企业为何反转？","digest":"7月9日，美股上市的基因疗法公司uniQure(NASDAQ:QURE)发布了AMT-130在治疗亨廷顿病的美国和欧洲I/II期临床试验积极中期数据，股价当日暴涨76.46%，随即在第二日再度暴涨51.72%，股价在两个交易日内累计涨幅167.72%。 而在2023年下半年，uniQure仍在大幅裁员，暂停并卖掉部分药物管线，同年的股价跌幅高达70.14%，一家陷入困境的药企为何在短期内重获资本市场的青睐？ 图片 专注于基因疗法的创新药企 Uniqure于1998年在荷兰的阿姆斯特丹成立，并于2014年5月在美国纳斯达克交易所上市，是一家致力为罕见病开发基因疗法的企业，第一个上市的基因疗法Glybera就是由Uniqure开发。 技术方面，Uniqure的基因疗法不但能表达缺失或者低表达的蛋白，而且也能沉默疾病基因。同时，公司的AAV5载体具有很好的免疫原性，几乎在所有观察到的抗AAV5抗体浓度中，对AAV5基因治疗的转导效率没有任何影响。 图片 适应症方面，Uniqure主要选择尚未有药物获批或现有疗法存在缺陷的罕见病，如血友病，亨廷顿病（Huntington Disease）、难治性颞叶癫痫（rTLE）、法布里病、肌萎缩侧索硬化症等。 2012年，uniQure的药物Glybera获得了欧盟药物管理机构批准，成为首个获批上市的基因疗法，该药物利用AAV载体将一个功能性脂蛋白脂肪酶（LPL）基因递送至骨骼肌，用于治疗脂蛋白脂肪酶缺乏症（LPLD）。 Glybera的上市奠定了uniQure在基因治疗领域的领导者地位，也吸引了大药企的合作。2015年，公司与百时美施贵宝与签署了一份高达10亿美元的独家合作协议，双方合作开发基因疗法用于心血管疾病领域多达10个靶标，BMS随后还入股uniQure，持股比例达9.9%。 不过Glyber的商业化不顺利，因误诊率高、市场需求少等原","plainDigest":"7月9日，美股上市的基因疗法公司uniQure(NASDAQ:QURE)发布了AMT-130在治疗亨廷顿病的美国和欧洲I/II期临床试验积极中期数据，股价当日暴涨76.46%，随即在第二日再度暴涨51.72%，股价在两个交易日内累计涨幅167.72%。 而在2023年下半年，uniQure仍在大幅裁员，暂停并卖掉部分药物管线，同年的股价跌幅高达70.14%，一家陷入困境的药企为何在短期内重获资本市场的青睐？ 图片 专注于基因疗法的创新药企 Uniqure于1998年在荷兰的阿姆斯特丹成立，并于2014年5月在美国纳斯达克交易所上市，是一家致力为罕见病开发基因疗法的企业，第一个上市的基因疗法Glybera就是由Uniqure开发。 技术方面，Uniqure的基因疗法不但能表达缺失或者低表达的蛋白，而且也能沉默疾病基因。同时，公司的AAV5载体具有很好的免疫原性，几乎在所有观察到的抗AAV5抗体浓度中，对AAV5基因治疗的转导效率没有任何影响。 图片 适应症方面，Uniqure主要选择尚未有药物获批或现有疗法存在缺陷的罕见病，如血友病，亨廷顿病（Huntington Disease）、难治性颞叶癫痫（rTLE）、法布里病、肌萎缩侧索硬化症等。 2012年，uniQure的药物Glybera获得了欧盟药物管理机构批准，成为首个获批上市的基因疗法，该药物利用AAV载体将一个功能性脂蛋白脂肪酶（LPL）基因递送至骨骼肌，用于治疗脂蛋白脂肪酶缺乏症（LPLD）。 Glybera的上市奠定了uniQure在基因治疗领域的领导者地位，也吸引了大药企的合作。2015年，公司与百时美施贵宝与签署了一份高达10亿美元的独家合作协议，双方合作开发基因疗法用于心血管疾病领域多达10个靶标，BMS随后还入股uniQure，持股比例达9.9%。 不过Glyber的商业化不顺利，因误诊率高、市场需求少等原","sourceLanguage":"CN","currentLanguage":"CN","editable":false,"auditStatus":"PASSED","topFlag":false,"totalScore":0,"gmtCreate":1724630775828,"gmtModify":1724643045214,"symbols":["QURE","QQQ","LLY","NVO","XBI"],"themeIds":[],"popularizeThemeFlag":false,"imageCount":3,"images":[{"url":"https://static.tigerbbs.com/9c7b3b55ca337bcc46354e8fa79a91ba","width":"669","height":"288"},{"url":"https://static.tigerbbs.com/0c82a0f1fb0496206f7f810cd8aed29b","width":"1080","height":"328"},{"url":"https://static.tigerbbs.com/e9353a241ab2e0fcf27553c744e4561e","width":"1080","height":"669"}],"repostCount":0,"viewCount":4420,"likeCount":0,"liked":false,"collected":false,"commentCount":0,"hotComments":[],"voteFlag":false,"rewardFlag":false,"videoFlag":false,"articleFlag":false,"paperFlag":true,"essentialFlag":false,"highlightedFlag":false,"shareLink":"https://laohu8.com/post/342467076857944","orderFlag":false,"starInvestorRankings":[],"featuresForAnalytics":[],"commentAndTweetFlag":false,"upFlag":false,"length":4121,"displayRows":4,"foldSize":0,"authorId":"3452938437060827"}],"position":0}],"size":9},"newsData":null,"noticeData":{"listData":[{"cdn_pdf":false,"hasAttachments":true,"id":"20801439","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000081-QURE","pdf_url":"","pub_time":1772661406000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/0001973379-26-000081-index.html","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000081/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEF4RyodYiJTrzfBqN","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-03-05 05:56","pubTimestamp":1772661406,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20799506","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000080-QURE","pdf_url":"","pub_time":1772600400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000080/0001973379-26-000080-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000080/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEFEdiCCoxQqG5NLdo","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-03-04 13:00","pubTimestamp":1772600400,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20799482","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000079-QURE","pdf_url":"","pub_time":1772600400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000079/0001973379-26-000079-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1536290/000197337926000079/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE4k5oUM4Fgt2YTCgE","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-03-04 13:00","pubTimestamp":1772600400,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20786504","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000068-QURE","pdf_url":"","pub_time":1772427600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000068/0001973379-26-000068-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1536290/000197337926000068/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE6Fc7VSAWkYYN91F4","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-03-02 13:00","pubTimestamp":1772427600,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20786399","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000067-QURE","pdf_url":"","pub_time":1772427600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000067/0001973379-26-000067-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000067/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILERBHY432XJYMS3up4","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-03-02 13:00","pubTimestamp":1772427600,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20786367","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000066-QURE","pdf_url":"","pub_time":1772427600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000066/0001973379-26-000066-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000066/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE42Ubk6W1FXQAR9Jx","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-03-02 13:00","pubTimestamp":1772427600,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20783972","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465926021898-QURE","pdf_url":"","pub_time":1772427600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]","symbol":"QURE","title":"Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]","titleType":"年度报告","type":"usFinancials","url":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/0001104659-26-021898-index.htm","us_notice_code":"Form 10-K","us_title_en":"Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"10-K","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231x10k.htm","primary":true,"translateUrl":"","linkName":"qure-20251231x10k.htm","type":"10-K","id":"NTFILE54MjwgMEXBES6NjQ","market":"us","size":4082297},{"description":"EX-4.1","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231xex4d1.htm","primary":false,"translateUrl":"","linkName":"qure-20251231xex4d1.htm","type":"EX-4.1","id":"NTFILEQYAcDZHnvRopmJ4p","market":"us","size":82040},{"description":"EX-10.22","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231xex10d22.htm","primary":false,"translateUrl":"","linkName":"qure-20251231xex10d22.htm","type":"EX-10.22","id":"NTFILEGBVRWdfZZGPTA2fF","market":"us","size":14263},{"description":"EX-14.1","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231xex14d1.htm","primary":false,"translateUrl":"","linkName":"qure-20251231xex14d1.htm","type":"EX-14.1","id":"NTFILE9PitwTZyE6qk7mLk","market":"us","size":47230},{"description":"EX-21.1","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231xex21d1.htm","primary":false,"translateUrl":"","linkName":"qure-20251231xex21d1.htm","type":"EX-21.1","id":"NTFILE8PKNwwpRrKuvSRk6","market":"us","size":8694},{"description":"EX-23.1","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231xex23d1.htm","primary":false,"translateUrl":"","linkName":"qure-20251231xex23d1.htm","type":"EX-23.1","id":"NTFILE9ifVfTgYdQDG7h66","market":"us","size":2518},{"description":"EX-31.1","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231xex31d1.htm","primary":false,"translateUrl":"","linkName":"qure-20251231xex31d1.htm","type":"EX-31.1","id":"NTFILE5Z69UpsdKB47m5TG","market":"us","size":14221},{"description":"EX-31.2","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231xex31d2.htm","primary":false,"translateUrl":"","linkName":"qure-20251231xex31d2.htm","type":"EX-31.2","id":"NTFILEHJikmdBoVRCQVQFw","market":"us","size":14132},{"description":"EX-32.1","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231xex32d1.htm","primary":false,"translateUrl":"","linkName":"qure-20251231xex32d1.htm","type":"EX-32.1","id":"NTFILEDBjVAmrpfNEfg7TS","market":"us","size":12863},{"description":"GRAPHIC","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231x10k001.jpg","primary":false,"translateUrl":"","linkName":"qure-20251231x10k001.jpg","type":"GRAPHIC","id":"NTFILEGHsBtKb3BZPSCau5","market":"us","size":5737},{"description":"GRAPHIC","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021898/qure-20251231x10k002.jpg","primary":false,"translateUrl":"","linkName":"qure-20251231x10k002.jpg","type":"GRAPHIC","id":"NTFILE8SmehHeoypVyU12r","market":"us","size":36162}],"type_name":"财务报告","type_name_en":"Financial Report","titleTypeEn":"Annual Report","us_type":"usFinancials","us_type_zh":"财务报告","earn_infos":[],"event_type":"important_notice","event_name":"年度报告","pubTime":"2026-03-02 13:00","pubTimestamp":1772427600,"title_zh":"Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20783867","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465926021890-QURE","pdf_url":"","pub_time":1772427600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 8-K - Current report","symbol":"QURE","title":"Form 8-K - Current report","titleType":"重要事件披露","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021890/0001104659-26-021890-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021890/qure-20260302xex99d1.htm","primary":true,"translateUrl":"","linkName":"qure-20260302xex99d1.htm","type":"EX-99.1","id":"NTFILE7hQWF14V6uCjHKHu","market":"us","size":179611},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021890/qure-20260302x8k.htm","primary":false,"translateUrl":"","linkName":"qure-20260302x8k.htm","type":"8-K","id":"NTFILE6ipKG79JNXtzqwib","market":"us","size":39814},{"description":"EX-99.2","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021890/qure-20260302xex99d2.htm","primary":false,"translateUrl":"","linkName":"qure-20260302xex99d2.htm","type":"EX-99.2","id":"NTFILE2XHj6qH85U7zqFzQ","market":"us","size":12825},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021890/qure-20260302xex99d1001.jpg","primary":false,"translateUrl":"","linkName":"qure-20260302xex99d1001.jpg","type":"GRAPHIC","id":"NTFILE6sNrDEQR5YiXSXfJ","market":"us","size":5856},{"description":"GRAPHIC","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926021890/qure-20260302xex99d2001.jpg","primary":false,"translateUrl":"","linkName":"qure-20260302xex99d2001.jpg","type":"GRAPHIC","id":"NTFILEDMuQKEepZipHZ6b9","market":"us","size":4809}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"重要事件披露","pubTime":"2026-03-02 13:00","pubTimestamp":1772427600,"title_zh":"Form 8-K - Current report","summary_en":"Item 2.02: Results of Operations and Financial Condition;\nItem 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"项目2.02：经营业绩和财务状况；第7.01项：法规FD披露；项目9.01：财务报表和附件","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20765319","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000048-QURE","pdf_url":"","pub_time":1771995600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000048/0001973379-26-000048-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1536290/000197337926000048/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEfy9g1nf438mq3EJw","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-02-25 13:00","pubTimestamp":1771995600,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20765276","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000047-QURE","pdf_url":"","pub_time":1771995600000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000047/0001973379-26-000047-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000047/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEHqaMKPMxWPqacPbv","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-02-25 13:00","pubTimestamp":1771995600,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20627553","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465926003075-QURE","pdf_url":"","pub_time":1768280400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 8-K - Current report","symbol":"QURE","title":"Form 8-K - Current report","titleType":"重要事件披露","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/0001104659-26-003075-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1.htm","primary":true,"translateUrl":"","linkName":"qure-20260113xex99d1.htm","type":"EX-99.1","id":"NTFILEHdWwrr345iFk6RYn","market":"us","size":48465},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113x8k.htm","primary":false,"translateUrl":"","linkName":"qure-20260113x8k.htm","type":"8-K","id":"NTFILE81T7z4GR7FJ1p4fp","market":"us","size":35193},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g001.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g001.jpg","type":"GRAPHIC","id":"NTFILEBXyDxfRQpcJEwSgk","market":"us","size":91323},{"description":"GRAPHIC","seq":4,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g002.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g002.jpg","type":"GRAPHIC","id":"NTFILEC6Ked51mDqBAJdT7","market":"us","size":218201},{"description":"GRAPHIC","seq":5,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g003.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g003.jpg","type":"GRAPHIC","id":"NTFILE4qf7zEzqmj7je3vK","market":"us","size":126226},{"description":"GRAPHIC","seq":6,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g004.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g004.jpg","type":"GRAPHIC","id":"NTFILE9BKM5g2xUHaXBnUn","market":"us","size":98398},{"description":"GRAPHIC","seq":7,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g005.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g005.jpg","type":"GRAPHIC","id":"NTFILEHzSCcfGPT3yHzjGN","market":"us","size":81505},{"description":"GRAPHIC","seq":8,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g006.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g006.jpg","type":"GRAPHIC","id":"NTFILE2PEhSUt1huLFPRcB","market":"us","size":99448},{"description":"GRAPHIC","seq":9,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g007.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g007.jpg","type":"GRAPHIC","id":"NTFILEnyAbv3i8MnEocmLf","market":"us","size":65258},{"description":"GRAPHIC","seq":10,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g008.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g008.jpg","type":"GRAPHIC","id":"NTFILE4svBofcMa89xHjHJ","market":"us","size":102880},{"description":"GRAPHIC","seq":11,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g009.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g009.jpg","type":"GRAPHIC","id":"NTFILEH6ZchBt1j8ohvkdz","market":"us","size":92953},{"description":"GRAPHIC","seq":12,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g010.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g010.jpg","type":"GRAPHIC","id":"NTFILEFjvzq5TbdTLDxgmq","market":"us","size":85636},{"description":"GRAPHIC","seq":13,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g011.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g011.jpg","type":"GRAPHIC","id":"NTFILEA4iUtDxJyosDa3zs","market":"us","size":102321},{"description":"GRAPHIC","seq":14,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g012.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g012.jpg","type":"GRAPHIC","id":"NTFILEEA5zdeZhxe6DWkt7","market":"us","size":93225},{"description":"GRAPHIC","seq":15,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g013.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g013.jpg","type":"GRAPHIC","id":"NTFILE2EmvcCGHZuAsyjxq","market":"us","size":108177},{"description":"GRAPHIC","seq":16,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g014.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g014.jpg","type":"GRAPHIC","id":"NTFILE7Pa35JMGNnN2pcSM","market":"us","size":91003},{"description":"GRAPHIC","seq":17,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g015.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g015.jpg","type":"GRAPHIC","id":"NTFILE4LWtPzrdR2a15jKr","market":"us","size":89584},{"description":"GRAPHIC","seq":18,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g016.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g016.jpg","type":"GRAPHIC","id":"NTFILEHDzoNfoyR7nYhygR","market":"us","size":89547},{"description":"GRAPHIC","seq":19,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g017.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g017.jpg","type":"GRAPHIC","id":"NTFILEBb2HF31iMMyJaogA","market":"us","size":68617},{"description":"GRAPHIC","seq":20,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g018.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g018.jpg","type":"GRAPHIC","id":"NTFILECemWk86KMbwrU5Hd","market":"us","size":91643},{"description":"GRAPHIC","seq":21,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g019.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g019.jpg","type":"GRAPHIC","id":"NTFILE5M98PZu9QQdQBPhy","market":"us","size":83375},{"description":"GRAPHIC","seq":22,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g020.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g020.jpg","type":"GRAPHIC","id":"NTFILE2rJS2xrC4YhdwJ7f","market":"us","size":116728},{"description":"GRAPHIC","seq":23,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g021.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g021.jpg","type":"GRAPHIC","id":"NTFILEBc6ojtSEoafxdMkm","market":"us","size":92564},{"description":"GRAPHIC","seq":24,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g022.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g022.jpg","type":"GRAPHIC","id":"NTFILE39iBoTBSLHkuaswB","market":"us","size":95463},{"description":"GRAPHIC","seq":25,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g023.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g023.jpg","type":"GRAPHIC","id":"NTFILEEZuyUGQqjx9hTHT3","market":"us","size":68776},{"description":"GRAPHIC","seq":26,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g024.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g024.jpg","type":"GRAPHIC","id":"NTFILED2hV6HCX3dh6dp6Y","market":"us","size":76971},{"description":"GRAPHIC","seq":27,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g025.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g025.jpg","type":"GRAPHIC","id":"NTFILEGpFEaiVNuUvavLrS","market":"us","size":66097},{"description":"GRAPHIC","seq":28,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g026.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g026.jpg","type":"GRAPHIC","id":"NTFILEGf6quR3VZKMNjtzz","market":"us","size":80683},{"description":"GRAPHIC","seq":29,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g027.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g027.jpg","type":"GRAPHIC","id":"NTFILEJ38Ar5pyxS34ytZR","market":"us","size":77416},{"description":"GRAPHIC","seq":30,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g028.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g028.jpg","type":"GRAPHIC","id":"NTFILE6o2byt1NxbyBKyqq","market":"us","size":85903},{"description":"GRAPHIC","seq":31,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g029.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g029.jpg","type":"GRAPHIC","id":"NTFILE42UPTyG92mBjfTgP","market":"us","size":84089},{"description":"GRAPHIC","seq":32,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g030.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g030.jpg","type":"GRAPHIC","id":"NTFILE4CCTiaAawrMMgpdt","market":"us","size":72780},{"description":"GRAPHIC","seq":33,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g031.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g031.jpg","type":"GRAPHIC","id":"NTFILE36qYqA7Ad1NoK9MN","market":"us","size":74342},{"description":"GRAPHIC","seq":34,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g032.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g032.jpg","type":"GRAPHIC","id":"NTFILECA6z21N9aVqiugt9","market":"us","size":75605},{"description":"GRAPHIC","seq":35,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g033.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g033.jpg","type":"GRAPHIC","id":"NTFILE74vQfzDPxz6TW8Wt","market":"us","size":96392},{"description":"GRAPHIC","seq":36,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926003075/qure-20260113xex99d1g034.jpg","primary":false,"translateUrl":"","linkName":"qure-20260113xex99d1g034.jpg","type":"GRAPHIC","id":"NTFILEDKp5h7DTT1xEunub","market":"us","size":19035}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"重要事件披露","pubTime":"2026-01-13 13:00","pubTimestamp":1768280400,"title_zh":"Form 8-K - Current report","summary_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"第7.01项：法规FD披露；项目9.01：财务报表和附件","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20624917","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000009-QURE","pdf_url":"","pub_time":1768194000000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000009/0001973379-26-000009-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000009/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILEHsk6V45BJPWYLAwj","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-01-12 13:00","pubTimestamp":1768194000,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20621004","market":"us","labels":[],"media":"sec.gov","original_id":"AN197337926000004-QURE","pdf_url":"","pub_time":1767934800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 144 - Report of proposed sale of securities","symbol":"QURE","title":"Form 144 - Report of proposed sale of securities","titleType":"关联方拟减持公告","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000197337926000004/0001973379-26-000004-index.htm","us_notice_code":"Form 144","us_title_en":"Form 144 - Report of proposed sale of securities","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1376099/000197337926000004/xsl144X01/primary_doc.xml","primary":true,"translateUrl":"","linkName":"primary_doc.html","type":"144","id":"NTFILE84ZjSC1JMVSgtHBQ","market":"us","size":0}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Proposed Sale Of Securities","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"关联方拟减持公告","pubTime":"2026-01-09 13:00","pubTimestamp":1767934800,"title_zh":"Form 144 - Report of proposed sale of securities","summary_en":"","summary_zh":"","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20619465","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465926002317-QURE","pdf_url":"","pub_time":1767934800000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 8-K - Current report","symbol":"QURE","title":"Form 8-K - Current report","titleType":"重要事件披露","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926002317/0001104659-26-002317-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926002317/qure-20260109xex99d1.htm","primary":true,"translateUrl":"","linkName":"qure-20260109xex99d1.htm","type":"EX-99.1","id":"NTFILE2vM4utLgPsUDTFV3","market":"us","size":14107},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926002317/qure-20260109x8k.htm","primary":false,"translateUrl":"","linkName":"qure-20260109x8k.htm","type":"8-K","id":"NTFILEEEE98StBaWrVVj15","market":"us","size":35030},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465926002317/qure-20260109xex99d1001.jpg","primary":false,"translateUrl":"","linkName":"qure-20260109xex99d1001.jpg","type":"GRAPHIC","id":"NTFILEH4QVAocAEqyRCSyE","market":"us","size":5856}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"重要事件披露","pubTime":"2026-01-09 13:00","pubTimestamp":1767934800,"title_zh":"Form 8-K - Current report","summary_en":"Item 7.01: Regulation FD Disclosure;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"第7.01项：法规FD披露；项目9.01：财务报表和附件","notice_type":"","filling_tag":"","gpt_icon":0},{"cdn_pdf":false,"hasAttachments":true,"id":"20489642","market":"us","labels":[],"media":"sec.gov","original_id":"AN110465925118292-QURE","pdf_url":"","pub_time":1764824400000,"showTitleType":true,"size":0,"source":"sec_us","summary":"Form 8-K - Current report","symbol":"QURE","title":"Form 8-K - Current report","titleType":"重要事件披露","type":"usAnnouncement","url":"https://www.sec.gov/Archives/edgar/data/1590560/000110465925118292/0001104659-25-118292-index.htm","us_notice_code":"Form 8-K","us_title_en":"Item 7.01: Regulation FD Disclosure;\nItem 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","is_important":0,"hasEarnInfos":false,"gpt_zh_title":"","gpt_en_title":"","attachments":[{"description":"EX-99.1","seq":1,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465925118292/qure-20251204xex99d1.htm","primary":true,"translateUrl":"","linkName":"qure-20251204xex99d1.htm","type":"EX-99.1","id":"NTFILEC5J7opuFg6ncN3QH","market":"us","size":16955},{"description":"8-K","seq":2,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465925118292/qure-20251204x8k.htm","primary":false,"translateUrl":"","linkName":"qure-20251204x8k.htm","type":"8-K","id":"NTFILE5JZtvqbsmofFGw5F","market":"us","size":42402},{"description":"GRAPHIC","seq":3,"linkUrl":"https://www.sec.gov/Archives/edgar/data/1590560/000110465925118292/qure-20251204xex99d1001.jpg","primary":false,"translateUrl":"","linkName":"qure-20251204xex99d1001.jpg","type":"GRAPHIC","id":"NTFILE5cs36cjzZ5psiden","market":"us","size":4085}],"type_name":"交易披露","type_name_en":"Transaction Related","titleTypeEn":"Major Issues Report","us_type":"usAnnouncement","us_type_zh":"交易披露","earn_infos":[],"event_type":"important_notice","event_name":"重要事件披露","pubTime":"2025-12-04 13:00","pubTimestamp":1764824400,"title_zh":"Form 8-K - Current report","summary_en":"Item 7.01: Regulation FD Disclosure;\nItem 8.01: Other Events;\nItem 9.01: Financial Statements and Exhibits","summary_zh":"第7.01项：法规FD披露；项目8.01：其他事件；项目9.01：财务报表和附件","notice_type":"","filling_tag":"","gpt_icon":0}],"currentPage":1,"bottom":false},"companyData":{"profile":{"websiteUrl":"http://www.uniqure.com","stockEarnings":[{"period":"1week","weight":0.9425},{"period":"1month","weight":-0.3259},{"period":"3month","weight":-0.1109},{"period":"6month","weight":0.0652},{"period":"1year","weight":0.4048},{"period":"ytd","weight":-0.2662}],"compareEarnings":[{"period":"1week","weight":-0.0128},{"period":"1month","weight":-0.0254},{"period":"3month","weight":-0.0186},{"period":"6month","weight":0.0288},{"period":"1year","weight":0.2166},{"period":"ytd","weight":-0.0082}],"compareStock":{"symbol":"SPY","name":"标普500ETF"},"description":"uniQure N.V.作为私人有限责任公司于2012年1月9日依照荷兰相关法律条文成立。公司是一家专业从事基因治疗的生物技术企业，致力于为罕见病和重病患者开发单一治疗途径。其管线包括针对亨廷顿病、与SOD1突变相关的肌萎缩性侧索硬化症、难治性中位颞叶癫痫和法布里病的临床候选药物，反映了对推进基因治疗领域创新疗法的关注。","yearOnYearQuotes":[{"month":1,"riseRate":0.25,"avgChangeRate":-0.009035},{"month":2,"riseRate":0.5,"avgChangeRate":0.032875},{"month":3,"riseRate":0.307692,"avgChangeRate":-0.040462},{"month":4,"riseRate":0.416667,"avgChangeRate":0.018299},{"month":5,"riseRate":0.666667,"avgChangeRate":0.042965},{"month":6,"riseRate":0.416667,"avgChangeRate":-0.009437},{"month":7,"riseRate":0.25,"avgChangeRate":0.033059},{"month":8,"riseRate":0.5,"avgChangeRate":0.005984},{"month":9,"riseRate":0.25,"avgChangeRate":0.122705},{"month":10,"riseRate":0.5,"avgChangeRate":0.060394},{"month":11,"riseRate":0.75,"avgChangeRate":0.0616},{"month":12,"riseRate":0.25,"avgChangeRate":0.125134}],"exchange":"NASDAQ","name":"uniQure N.V.","nameEN":"uniQure NV"},"aProfile":null}}}