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Evommune(EVMN)
28.88
+0.81
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牛唐
·
2025-12-15
超22亿元，年内规模最大的生物医药IPO诞生
2025年11月，在生物医药领域，有2家公司以IPO的方式赴美上市，市场较为清淡。 但从募集规模来看，11月上市的BillionToOne位列今年第一大规模的生物医药IPO，超过了9月上市的LB Pharmaceuticals（2.85亿美元）、1月上市的Metsera（2.75亿美元）。 图片 1、Evommune(NYSE:EVMN) 11月7日，Evommune在纽约交易所上市，发行价为每股16美元，发行937.5万股，融资规模达1.5亿美元。 Evommune成立于2020年，是一家成专注于开发治疗免疫介导炎症性疾病药物公司。创始团队来自被礼来以11亿美元收购的皮肤病药物公司Dermira(NASDAQ:DERM)。 目前，Evommune共有两个个在研药物： EVO756：一款强效且高选择性的MRGPRX2口服小分子拮抗剂。靶标MRGPRX2是G蛋白偶联受体（GPCR）家族成员，主要表达于肥大细胞表面，其激活机制与经典IgE介导的过敏反应不同，属于“非经典激活”通路。该受体可被多种内源性（如神经肽、抗菌肽）和外源性（如药物、化学刺激物）配体激活，触发肥大细胞脱颗粒，释放组胺、蛋白酶等炎症介质，导致伪过敏反应、慢性炎症及瘙痒等症状。 EVO756的主要适应症是慢性荨麻疹，今年5月发布的临床2期研究显示，300mg每日一次或50mg每日两次给药4周后，总体改善率达 93%，瘙痒评分（Pruritus NRS）较基线下降约50%，在安全性和药效上均达到慢性荨麻疹治疗的主要治疗终点。此外，EVO756还于8月启动特应性皮炎的临床二期研究。 EVO301：一款长效融合蛋白，由IL-18结合蛋白（IL-18BP）与抗血清白蛋白Fab相关结构域组成。该药物由韩国生物技术公司AprilBio授权，Evommune于2024年获得许可。IL-18是IL-1家族的一种促炎性细胞因子，
超22亿元，年内规模最大的生物医药IPO诞生
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小虎周报
·
2025-11-10
【一周IPO观察】新股“冰火两重天”，“二进宫”受挫；海伟电子过讯，10股递表；美股科技医药表现亮眼
港股IPO观察截止2025年的第45周，港交所7家上市，7家招股，1家聆讯，10家递表当周上市（7家，其中1家转板）数据智能应用软件供应商
$明略科技-W(02718)$
（首日+106.10%）新能源汽车龙头企业
$赛力斯(09927)$
（首日+0）生殖健康生物医药公司
$旺山旺水-B(02630)$
（首日+145.73%）L4级自动驾驶领域的全球先行者
$文远知行-W(00800)$
（首日-9.96%）Robotaxi公司
$小马智行-W(02026)$
（首日-9.28%）A+H智能汽车科技解决方案提供商
$均胜电子(00699)$
（首日-8.00%）
$大洋环球控股(09876)$
成功从GEM转至主板上市当周招股（3家新）
$乐舒适(02698)$
$中伟新材(02579)$
$百利天恒(02615)$
通过聆讯（2家）中国第二大的电容器薄膜制造商海伟
【一周IPO观察】新股“冰火两重天”，“二进宫”受挫；海伟电子过讯，10股递表；美股科技医药表现亮眼
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小虎周报
·
2025-11-03
【一周IPO观察】新股续涨，明略暗盘翻倍，乐舒适招股，33股港股递表；杜邦分拆Q上市，军工科技BETA本周美股上市
港股IPO观察截止2025年的第44周，港交所4家上市，5家招股，2家聆讯，25家递表当周上市（3家）
$滴普科技(01384)$
（首日+20.6%）
$剑桥科技(06166)$
（首日+36.90%）
$八马茶业(06980)$
（首日+78.80%）
$三一重工(06031)$
（首日-2.44%）当周招股（7家）数据智能应用软件供应商
$明略科技-W(02718)$
（暗盘+110.64%）新能源汽车龙头企业
$赛力斯(09927)$
生殖健康生物医药公司
$旺山旺水-B(02630)$
L4级自动驾驶领域的全球先行者
$文远知行-W(00800)$
Robotaxi公司
$小马智行-W(02026)$
A+H智能汽车科技解决方案提供商
$均胜电子(00699)$
跨国卫生用品公司乐舒适通过聆讯（2家）跨国卫生用品公司
【一周IPO观察】新股续涨，明略暗盘翻倍，乐舒适招股，33股港股递表；杜邦分拆Q上市，军工科技BETA本周美股上市
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公司概况
公司名称
Evommune
所属市场
NYSE
成立日期
- -
员工人数
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办公地址
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公司网址
http://www.evommune.com
邮政编码
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联系电话
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联系传真
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公司概况
Evommune, Inc.是一家于2020年4月在特拉华州注册成立的公司，总部位于加利福尼亚州的帕洛阿尔托。该公司是一家临床阶段的生物技术公司，专注于针对慢性炎症疾病主要致病因素的创新治疗方案开发。其初步临床开发项目集中在慢性自发性荨麻疹、特应性皮炎和溃疡性结肠炎上。
04-17
招股说明书
Form S-1 - General form for registration of securities under the Securities Act of 1933
Form S-1 - General form for registration of securities under the Securities Act of 1933
04-13
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
03-06
员工持股计划
Form S-8 - Securities to be offered to employees in employee benefit plans
Form S-8 - Securities to be offered to employees in employee benefit plans
03-05
年度报告
Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]
Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405]
03-05
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
02-13
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
02-10
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
2025-12-11
季度报告
Form 10-Q - Quarterly report [Sections 13 or 15(d)]
Form 10-Q - Quarterly report [Sections 13 or 15(d)]
2025-12-11
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
2025-11-07
员工持股计划
Form S-8 - Securities to be offered to employees in employee benefit plans
Form S-8 - Securities to be offered to employees in employee benefit plans
2025-11-07
重要事件披露
Form 8-K - Current report
Form 8-K - Current report
2025-11-06
[补充]招股说明书
Form FWP - Filing under Securities Act Rules 163/433 of free writing prospectuses
Form FWP - Filing under Securities Act Rules 163/433 of free writing prospectuses
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日
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最高
28.88
今开
28.61
量比
0.36
最低
28.07
昨收
28.07
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