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funkykoh

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- funkykohfunkykoh
  ·2021-06-24
  Yay finally got a T!
  1,805 1
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- funkykohfunkykoh
  ·2021-06-23
  Hmmm
  非常抱歉，此主贴已删除
  1,655 评论
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- funkykohfunkykoh
  ·2021-06-22
  Yes
  Goldman Sees Another $500 Billion Being Plowed Into U.S. Stocks<blockquote>高盛预计另外 5000 亿美元将投入美国股市</blockquote>
  (Bloomberg) -- Households and corporations will buy an additional $500 billion of U.S. stocks throug
  Goldman Sees Another $500 Billion Being Plowed Into U.S. Stocks<blockquote>高盛预计另外 5000 亿美元将投入美国股市</blockquote>
  1,913 2
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- funkykohfunkykoh
  ·2021-06-22
  Good
  非常抱歉，此主贴已删除
  1,905 评论
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- funkykohfunkykoh
  ·2021-06-21
  Wow
  Orphazyme rose more than 6% in premarket trading<blockquote>Orphazyme 在盘前交易中上涨超过 6%</blockquote>
  (June 21) Orphazyme rose more than 6% in premarket trading. What happened Shares of Orphazyme, a c
  Orphazyme rose more than 6% in premarket trading<blockquote>Orphazyme 在盘前交易中上涨超过 6%</blockquote>
  1,940 评论
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- funkykohfunkykoh
  ·2021-06-17
  Oh
  Toplines Before US Market Open on Wednesday<blockquote>周三美国市场开盘前的顶线</blockquote>
  U.S. stock index futures were mostly flat on Wednesday ahead of the Federal Reserve's update on mone
  Toplines Before US Market Open on Wednesday<blockquote>周三美国市场开盘前的顶线</blockquote>
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- funkykohfunkykoh
  ·2021-06-13
  But the risk is small and may have other triggering factors
  非常抱歉，此主贴已删除
  1,856 评论
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- funkykohfunkykoh
  ·2021-05-11
  All crashing
  非常抱歉，此主贴已删除
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- funkykohfunkykoh
  ·2021-05-11
  To sell or to keep?
  非常抱歉，此主贴已删除
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- funkykohfunkykoh
  ·2021-04-20
  Okay
  非常抱歉，此主贴已删除
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11:23","market":"us","language":"en","title":"Goldman Sees Another $500 Billion Being Plowed Into U.S. Stocks<blockquote>高盛预计另外 5000 亿美元将投入美国股市</blockquote>","url":"https://stock-news.laohu8.com/highlight/detail?id=1134679198","media":"finance.yahoo","summary":"(Bloomberg) -- Households and corporations will buy an additional $500 billion of U.S. stocks throug","content":"<p>(Bloomberg) -- Households and corporations will buy an additional $500 billion of U.S. stocks through the year-end, even as equities trade near record highs, according to Goldman Sachs Group Inc.</p><p><blockquote>（彭博社）——据高盛集团称，到今年年底，家庭和企业将额外购买 5000 亿美元的美国股票，尽管股票交易接近历史新高。</blockquote></p><p> The splurge is set to happen amid a record $5.5 trillion of cash that’s sitting idle, having swollen through the pandemic, Goldman strategists led by David J. Kostin wrote in a note. They expect corporations to be the biggest source of equity demand for the rest of 2021, with buybacks set to accelerate and issuance poised to slow from peak first-quarter levels.</p><p><blockquote>以大卫-J-科斯汀（David J. Kostin）为首的高盛策略师在一份报告中写道，这笔挥霍将在创纪录的 5.5 万亿美元现金闲置的情况下发生，这些现金在大流行病期间不断膨胀。他们预计，在 2021 年剩余时间里，企业将成为最大的股票需求来源，回购将加速，发行量将从第一季度的峰值水平放缓。</blockquote></p><p> In the first quarter, households bought a net $172 billion of equities, Goldman said, with demand set to be boosted further by swollen levels of cash and growing market participation by retail investors that has led to the wild swings seen in so-called meme stocks this year.</p><p><blockquote>高盛表示，第一季度，家庭净购买了 1,720 亿美元的股票，现金水平膨胀和散户投资者不断增加的市场参与度将进一步提振需求，导致今年所谓的模因股票出现剧烈波动。</blockquote></p><p> Investor appetite for equities shows no sign of abating, even as U.S. and European stocks trade close to record highs and as U.S. Federal Reserve officials signal they’re getting ready to scale back stimulus.</p><p><blockquote>尽管美国和欧洲股市接近历史新高，美国联邦储备委员会官员也表示准备缩减刺激措施，但投资者对股票的兴趣丝毫没有减弱的迹象。</blockquote></p><p></p>","source":"lsy1612507957220","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Goldman Sees Another $500 Billion Being Plowed Into U.S. Stocks<blockquote>高盛预计另外 5000 亿美元将投入美国股市</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nGoldman Sees Another $500 Billion Being Plowed Into U.S. Stocks<blockquote>高盛预计另外 5000 亿美元将投入美国股市</blockquote>\n</h2>\n<h4 class=\"meta\">\n<p class=\"head\">\n<strong class=\"h-name small\">finance.yahoo</strong><span class=\"h-time small\">2021-06-22 11:23</span>\n</p>\n</h4>\n</header>\n<article>\n<p>(Bloomberg) -- Households and corporations will buy an additional $500 billion of U.S. stocks through the year-end, even as equities trade near record highs, according to Goldman Sachs Group Inc.</p><p><blockquote>（彭博社）——据高盛集团称，到今年年底，家庭和企业将额外购买 5000 亿美元的美国股票，尽管股票交易接近历史新高。</blockquote></p><p> The splurge is set to happen amid a record $5.5 trillion of cash that’s sitting idle, having swollen through the pandemic, Goldman strategists led by David J. Kostin wrote in a note. They expect corporations to be the biggest source of equity demand for the rest of 2021, with buybacks set to accelerate and issuance poised to slow from peak first-quarter levels.</p><p><blockquote>以大卫-J-科斯汀（David J. Kostin）为首的高盛策略师在一份报告中写道，这笔挥霍将在创纪录的 5.5 万亿美元现金闲置的情况下发生，这些现金在大流行病期间不断膨胀。他们预计，在 2021 年剩余时间里，企业将成为最大的股票需求来源，回购将加速，发行量将从第一季度的峰值水平放缓。</blockquote></p><p> In the first quarter, households bought a net $172 billion of equities, Goldman said, with demand set to be boosted further by swollen levels of cash and growing market participation by retail investors that has led to the wild swings seen in so-called meme stocks this year.</p><p><blockquote>高盛表示，第一季度，家庭净购买了 1,720 亿美元的股票，现金水平膨胀和散户投资者不断增加的市场参与度将进一步提振需求，导致今年所谓的模因股票出现剧烈波动。</blockquote></p><p> Investor appetite for equities shows no sign of abating, even as U.S. and European stocks trade close to record highs and as U.S. Federal Reserve officials signal they’re getting ready to scale back stimulus.</p><p><blockquote>尽管美国和欧洲股市接近历史新高，美国联邦储备委员会官员也表示准备缩减刺激措施，但投资者对股票的兴趣丝毫没有减弱的迹象。</blockquote></p><p></p>\n<div class=\"bt-text\">\n\n\n<p> 来源：<a href=\"https://finance.yahoo.com/news/goldman-sees-another-500-billion-120837569.html\">finance.yahoo</a></p>\n<p>为提升您的阅读体验，我们对本页面进行了排版优化</p>\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"GS":"高盛"},"source_url":"https://finance.yahoo.com/news/goldman-sees-another-500-billion-120837569.html","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1134679198","content_text":"(Bloomberg) -- Households and corporations will buy an additional $500 billion of U.S. stocks through the year-end, even as equities trade near record highs, according to Goldman Sachs Group Inc.\nThe splurge is set to happen amid a record $5.5 trillion of cash that’s sitting idle, having swollen through the pandemic, Goldman strategists led by David J. Kostin wrote in a note. They expect corporations to be the biggest source of equity demand for the rest of 2021, with buybacks set to accelerate and issuance poised to slow from peak first-quarter levels.\nIn the first quarter, households bought a net $172 billion of equities, Goldman said, with demand set to be boosted further by swollen levels of cash and growing market participation by retail investors that has led to the wild swings seen in so-called meme stocks this year.\nInvestor appetite for equities shows no sign of abating, even as U.S. and European stocks trade close to record highs and as U.S. Federal Reserve officials signal they’re getting ready to scale back stimulus.","news_type":1,"symbols_score_info":{"GS":0.9}},"isVote":1,"tweetType":1,"viewCount":1913,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":120916632,"gmtCreate":1624291687426,"gmtModify":1631889099048,"author":{"id":"3582025009793897","authorId":"3582025009793897","name":"funkykoh","avatar":"https://static.tigerbbs.com/4d8ac2b302d0f306dda0b8972a050851","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3582025009793897","authorIdStr":"3582025009793897"},"themes":[],"title":"","htmlText":"Good","listText":"Good","text":"Good","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/120916632","repostId":"1127414335","repostType":4,"isVote":1,"tweetType":1,"viewCount":1905,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":167466964,"gmtCreate":1624282663258,"gmtModify":1631889099052,"author":{"id":"3582025009793897","authorId":"3582025009793897","name":"funkykoh","avatar":"https://static.tigerbbs.com/4d8ac2b302d0f306dda0b8972a050851","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3582025009793897","authorIdStr":"3582025009793897"},"themes":[],"title":"","htmlText":"Wow","listText":"Wow","text":"Wow","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/167466964","repostId":"1184501396","repostType":4,"repost":{"id":"1184501396","kind":"news","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1624267024,"share":"https://www.laohunote.com/m/news/1184501396?lang=zh_CN&edition=full","pubTime":"2021-06-21 17:17","market":"us","language":"en","title":"Orphazyme rose more than 6% in premarket trading<blockquote>Orphazyme 在盘前交易中上涨超过 6%</blockquote>","url":"https://stock-news.laohu8.com/highlight/detail?id=1184501396","media":"Tiger Newspress","summary":"(June 21) Orphazyme rose more than 6% in premarket trading. \n\nWhat happened\nShares of Orphazyme, a c","content":"<p>(June 21)&nbsp;Orphazyme rose more than 6% in premarket trading.&nbsp;</p><p><blockquote>（6月21日）Orphazyme在盘前交易中上涨超过6%。</blockquote></p><p> <img src=\"https://static.tigerbbs.com/a1e2eb27cc68ce74ddd21a64a64634cf\" tg-width=\"719\" tg-height=\"495\" referrerpolicy=\"no-referrer\"></p><p><blockquote></blockquote></p><p> <b>What happened</b></p><p><blockquote><b>发生了什么事</b></blockquote></p><p> Shares of&nbsp;<b>Orphazyme</b>, a clinical-stage biopharmaceutical company, got hammered after the Food and Drug Administration (FDA) refused to approve an application for the company's lead candidate. Investors are now uncertain when the biotech could have an approved product to sell, and pushed the stock 44.4% lower as of 12:12 p.m. EDT on last&nbsp;Friday.</p><p><blockquote>股份<b>奥尔法酶</b>在美国食品药品监督管理局 (FDA) 拒绝批准该公司主要候选人的申请后，一家临床阶段的生物制药公司受到了打击。投资者现在不确定这家生物技术公司何时可以销售获得批准的产品，截至美国东部时间中午 12:12，该股下跌 44.4%。上周五美国东部时间。</blockquote></p><p> <b>So what</b></p><p><blockquote><b>那又怎样</b></blockquote></p><p> The FDA began reviewing an application for Orphazyme's lead candidate arimoclomol last September as a potential treatment for a rare but life-threatening disease called Neimann-Pick Disease Type-C (NPC). Earlier this month, shares of Orphazymeshot upmore than 200% in anticipation of a green light that never came.</p><p><blockquote>FDA 去年 9 月开始审查 Orphazyme 的主要候选药物 arimoclomol 的申请，作为一种罕见但危及生命的疾病的潜在治疗方法，称为 Neimann-Pick 病 C 型 (NPC)。本月早些时候，Orphazyme 的股价上涨了 200% 以上，原因是预期从未到来的绿灯。</blockquote></p><p> Instead of an approval decision for arimoclomol, the agency asked for more information in the form of a complete response letter (CRL). That came as a shock to heaps of investors who were new to the complex world of drug development and were expecting a massiveshort squeeze.</p><p><blockquote>该机构没有做出arimoclomol的批准决定，而是以完整回复函（CRL）的形式要求提供更多信息。这让许多投资者感到震惊，他们刚刚接触复杂的药物开发世界，并预计会出现大规模的空头挤压。</blockquote></p><p> Many institutional investors were betting against Orphazyme because its lead candidate failed to achieve the primary endpoint in the pivotal study underpinning the application. Arimoclomol also failed to improve patients' scores on a secondary endpoint specifically requested by the FDA.</p><p><blockquote>许多机构投资者押注 Orphazyme，因为其主要候选药物未能在支撑该申请的关键研究中实现主要终点。Arimoclomol 也未能改善 FDA 特别要求的次要终点的患者评分。</blockquote></p><p> <b>Now what</b></p><p><blockquote><b>现在呢</b></blockquote></p><p> According to Orphazyme, the company needs to further substantiate the validity of the primary endpoint that arimoclomol almost achieved. To satisfy the FDA, the company will most likely have to run a new pivotal study.</p><p><blockquote>据Orphazyme称，该公司需要进一步证实arimoclomol几乎达到的主要终点的有效性。为了满足 FDA 的要求，该公司很可能不得不进行一项新的关键研究。</blockquote></p><p> Some shareholders remain hopeful that the European Medicines Agency will be less strict than the FDA. While the FDA's European colleague has been more lenient regarding treatments for rare diseases in the past, arimoclomol probably isn't moving forward until it produces some convincing clinical-trial results.</p><p><blockquote>一些股东仍然希望欧洲药品管理局不会像FDA那样严格。虽然FDA的欧洲同事过去在罕见疾病的治疗方面更加宽松，但arimoclomol可能不会向前推进，直到它产生一些令人信服的临床试验结果。</blockquote></p><p> Despite lacking a clear path forward, the Denmark-headquartered company still boasts a fairly large market cap in excess of $500 million at recent prices. Irrational expectations could keep it elevated, but this is way too high for anyclinical-stage biotechin Orphazyme's position.</p><p><blockquote>尽管缺乏明确的前进道路，这家总部位于丹麦的公司仍然拥有相当大的市值，按最近的价格计算，超过 5 亿美元。非理性的期望可能会使其保持较高水平，但对于任何临床阶段的生物技术公司 Orphazyme 的地位来说，这都太高了。</blockquote></p><p></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Orphazyme rose more than 6% in premarket trading<blockquote>Orphazyme 在盘前交易中上涨超过 6%</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nOrphazyme rose more than 6% in premarket trading<blockquote>Orphazyme 在盘前交易中上涨超过 6%</blockquote>\n</h2>\n<h4 class=\"meta\">\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Tiger Newspress </p>\n<p class=\"h-time smaller\">2021-06-21 17:17</p>\n</div>\n</a>\n</h4>\n</header>\n<article>\n<p>(June 21)&nbsp;Orphazyme rose more than 6% in premarket trading.&nbsp;</p><p><blockquote>（6月21日）Orphazyme在盘前交易中上涨超过6%。</blockquote></p><p> <img src=\"https://static.tigerbbs.com/a1e2eb27cc68ce74ddd21a64a64634cf\" tg-width=\"719\" tg-height=\"495\" referrerpolicy=\"no-referrer\"></p><p><blockquote></blockquote></p><p> <b>What happened</b></p><p><blockquote><b>发生了什么事</b></blockquote></p><p> Shares of&nbsp;<b>Orphazyme</b>, a clinical-stage biopharmaceutical company, got hammered after the Food and Drug Administration (FDA) refused to approve an application for the company's lead candidate. Investors are now uncertain when the biotech could have an approved product to sell, and pushed the stock 44.4% lower as of 12:12 p.m. EDT on last&nbsp;Friday.</p><p><blockquote>股份<b>奥尔法酶</b>在美国食品药品监督管理局 (FDA) 拒绝批准该公司主要候选人的申请后，一家临床阶段的生物制药公司受到了打击。投资者现在不确定这家生物技术公司何时可以销售获得批准的产品，截至美国东部时间中午 12:12，该股下跌 44.4%。上周五美国东部时间。</blockquote></p><p> <b>So what</b></p><p><blockquote><b>那又怎样</b></blockquote></p><p> The FDA began reviewing an application for Orphazyme's lead candidate arimoclomol last September as a potential treatment for a rare but life-threatening disease called Neimann-Pick Disease Type-C (NPC). Earlier this month, shares of Orphazymeshot upmore than 200% in anticipation of a green light that never came.</p><p><blockquote>FDA 去年 9 月开始审查 Orphazyme 的主要候选药物 arimoclomol 的申请，作为一种罕见但危及生命的疾病的潜在治疗方法，称为 Neimann-Pick 病 C 型 (NPC)。本月早些时候，Orphazyme 的股价上涨了 200% 以上，原因是预期从未到来的绿灯。</blockquote></p><p> Instead of an approval decision for arimoclomol, the agency asked for more information in the form of a complete response letter (CRL). That came as a shock to heaps of investors who were new to the complex world of drug development and were expecting a massiveshort squeeze.</p><p><blockquote>该机构没有做出arimoclomol的批准决定，而是以完整回复函（CRL）的形式要求提供更多信息。这让许多投资者感到震惊，他们刚刚接触复杂的药物开发世界，并预计会出现大规模的空头挤压。</blockquote></p><p> Many institutional investors were betting against Orphazyme because its lead candidate failed to achieve the primary endpoint in the pivotal study underpinning the application. Arimoclomol also failed to improve patients' scores on a secondary endpoint specifically requested by the FDA.</p><p><blockquote>许多机构投资者押注 Orphazyme，因为其主要候选药物未能在支撑该申请的关键研究中实现主要终点。Arimoclomol 也未能改善 FDA 特别要求的次要终点的患者评分。</blockquote></p><p> <b>Now what</b></p><p><blockquote><b>现在呢</b></blockquote></p><p> According to Orphazyme, the company needs to further substantiate the validity of the primary endpoint that arimoclomol almost achieved. To satisfy the FDA, the company will most likely have to run a new pivotal study.</p><p><blockquote>据Orphazyme称，该公司需要进一步证实arimoclomol几乎达到的主要终点的有效性。为了满足 FDA 的要求，该公司很可能不得不进行一项新的关键研究。</blockquote></p><p> Some shareholders remain hopeful that the European Medicines Agency will be less strict than the FDA. While the FDA's European colleague has been more lenient regarding treatments for rare diseases in the past, arimoclomol probably isn't moving forward until it produces some convincing clinical-trial results.</p><p><blockquote>一些股东仍然希望欧洲药品管理局不会像FDA那样严格。虽然FDA的欧洲同事过去在罕见疾病的治疗方面更加宽松，但arimoclomol可能不会向前推进，直到它产生一些令人信服的临床试验结果。</blockquote></p><p> Despite lacking a clear path forward, the Denmark-headquartered company still boasts a fairly large market cap in excess of $500 million at recent prices. Irrational expectations could keep it elevated, but this is way too high for anyclinical-stage biotechin Orphazyme's position.</p><p><blockquote>尽管缺乏明确的前进道路，这家总部位于丹麦的公司仍然拥有相当大的市值，按最近的价格计算，超过 5 亿美元。非理性的期望可能会使其保持较高水平，但对于任何临床阶段的生物技术公司 Orphazyme 的地位来说，这都太高了。</blockquote></p><p></p>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1184501396","content_text":"(June 21) Orphazyme rose more than 6% in premarket trading. \n\nWhat happened\nShares of Orphazyme, a clinical-stage biopharmaceutical company, got hammered after the Food and Drug Administration (FDA) refused to approve an application for the company's lead candidate. Investors are now uncertain when the biotech could have an approved product to sell, and pushed the stock 44.4% lower as of 12:12 p.m. EDT on last Friday.\nSo what\nThe FDA began reviewing an application for Orphazyme's lead candidate arimoclomol last September as a potential treatment for a rare but life-threatening disease called Neimann-Pick Disease Type-C (NPC). Earlier this month, shares of Orphazymeshot upmore than 200% in anticipation of a green light that never came.\nInstead of an approval decision for arimoclomol, the agency asked for more information in the form of a complete response letter (CRL). That came as a shock to heaps of investors who were new to the complex world of drug development and were expecting a massiveshort squeeze.\nMany institutional investors were betting against Orphazyme because its lead candidate failed to achieve the primary endpoint in the pivotal study underpinning the application. Arimoclomol also failed to improve patients' scores on a secondary endpoint specifically requested by the FDA.\nNow what\nAccording to Orphazyme, the company needs to further substantiate the validity of the primary endpoint that arimoclomol almost achieved. To satisfy the FDA, the company will most likely have to run a new pivotal study.\nSome shareholders remain hopeful that the European Medicines Agency will be less strict than the FDA. While the FDA's European colleague has been more lenient regarding treatments for rare diseases in the past, arimoclomol probably isn't moving forward until it produces some convincing clinical-trial results.\nDespite lacking a clear path forward, the Denmark-headquartered company still boasts a fairly large market cap in excess of $500 million at recent prices. Irrational expectations could keep it elevated, but this is way too high for anyclinical-stage biotechin Orphazyme's position.","news_type":1,"symbols_score_info":{"ORPH":0.9}},"isVote":1,"tweetType":1,"viewCount":1940,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":163343016,"gmtCreate":1623860473335,"gmtModify":1631889099052,"author":{"id":"3582025009793897","authorId":"3582025009793897","name":"funkykoh","avatar":"https://static.tigerbbs.com/4d8ac2b302d0f306dda0b8972a050851","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3582025009793897","authorIdStr":"3582025009793897"},"themes":[],"title":"","htmlText":"Oh","listText":"Oh","text":"Oh","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/163343016","repostId":"1185341836","repostType":4,"repost":{"id":"1185341836","kind":"news","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1623845207,"share":"https://www.laohunote.com/m/news/1185341836?lang=zh_CN&edition=full","pubTime":"2021-06-16 20:06","market":"sh","language":"en","title":"Toplines Before US Market Open on Wednesday<blockquote>周三美国市场开盘前的顶线</blockquote>","url":"https://stock-news.laohu8.com/highlight/detail?id=1185341836","media":"Tiger Newspress","summary":"U.S. stock index futures were mostly flat on Wednesday ahead of the Federal Reserve's update on mone","content":"<p>U.S. stock index futures were mostly flat on Wednesday ahead of the&nbsp;Federal Reserve's update&nbsp;on monetary policy.</p><p><blockquote>在美联储更新货币政策之前，美国股指期货周三基本持平。</blockquote></p><p> Futures contracts tied to the Dow Jones Industrial Average were just 46 points lower. S&amp;P 500 futures were largely flat, while Nasdaq 100 futures traded up by 0.1%.</p><p><blockquote>与道琼斯工业平均指数挂钩的期货合约仅下跌 46 点。标普500期货基本持平，而纳斯达克 100 指数期货上涨 0.1%。</blockquote></p><p> <p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/33b560b1ab96b7a340369b24c17d6aa2\" tg-width=\"664\" tg-height=\"233\" referrerpolicy=\"no-referrer\"><span>*Source From Tiger Trade, EST 08:10</span></p><p><blockquote><p class=\"t-img-caption\"><span>*来源：Tiger Trade，美国东部时间 08:10</span></p></blockquote></p><p> The Fed has previously tried to assuage concerns that rising inflation would prompt it to tighten its ultra loose monetary policy, but data on Tuesday showing a jump in producer prices has again raised expectations the central bank could begin debating closing the taps at its meeting this week.</p><p><blockquote>美联储此前曾试图缓解人们对通胀上升将促使其收紧超宽松货币政策的担忧，但周二显示生产者价格上涨的数据再次引发了人们对美联储可能在本周会议上开始讨论关闭水龙头的预期。</blockquote></p><p> The central bank's latest policy statement is expected to be released with fresh economic projections at 2 p.m. ET (1800 GMT).</p><p><blockquote>央行最新的政策声明预计将于美国东部时间下午2点（格林威治标准时间1800）发布，并附有新的经济预测。</blockquote></p><p> <b>Stocks making the biggest moves in the premarket:</b></p><p><blockquote><b>盘前涨幅最大的股票：</b></blockquote></p><p> <b>Oracle(ORCL) </b>– Oracleearned $1.54 per sharefor its latest quarter, beating the consensus estimate of $1.31 a share. The business software company's revenue topped estimates as well. The company forecast current-quarter profit below consensus, however, as it increases investment in its cloud computing operations. Its shares fell 4.7% in premarket trading.</p><p><blockquote><b>甲骨文(ORCL)</b>– 甲骨文最新季度每股收益为 1.54 美元，超出市场普遍预期的每股 1.31 美元。这家商业软件公司的收入也超出了预期。然而，随着该公司增加对云计算业务的投资，该公司预计本季度利润将低于市场预期。其股价在盘前交易中下跌 4.7%。</blockquote></p><p> <b>Roblox(RBLX) </b>– Roblox tumbled 7.7% in the premarket after it reported 43 million daily active users for May, up 28% compared to a year earlier but down from 43.3 million in April. Spending by users of the videogame platform was down slightly from a year earlier.</p><p><blockquote><b>机器人（RBLX）</b>– Roblox 公布 5 月份日活跃用户为 4300 万，同比增长 28%，但低于 4 月份的 4330 万，盘前暴跌 7.7%。视频游戏平台用户的支出比去年同期略有下降。</blockquote></p><p> <b>Kindred Biosciences(KIN)</b> – The pet therapeutics company agreed to be acquired byElanco Animal Health(ELAN) for $9.25 per share, or $440 million. Kindred had closed at $6.34 Tuesday, and its stock surged 44.6% in the premarket.</p><p><blockquote><b>Kindred Biosciences</b>– 这家宠物治疗公司同意被 Elanco Animal Health (ELAN) 以每股 9.25 美元（即 4.4 亿美元）收购。Kindred 周二收于 6.34 美元，其股价在盘前飙升 44.6%。</blockquote></p><p> <b>La-Z-Boy(LZB) </b>– La-Z-Boy reported quarterly earnings of 87 cents per share, compared to a consensus estimate of 74 cents a share. The company best known for its reclining chairs also reported better-than-expected revenue. La-Z-Boy said it was being impacted by supply chain issues and significant increases in raw materials prices. Its shares lost 2.3% in the premarket.</p><p><blockquote><b>拉-Z-男孩(LZB)</b>– La-Z-Boy 公布的季度收益为每股 87 美分，而市场普遍预期为每股 74 美分。这家以躺椅而闻名的公司也公布了好于预期的收入。La-Z-Boy表示，该公司受到供应链问题和原材料价格大幅上涨的影响。其股价在盘前下跌 2.3%。</blockquote></p><p> <b>H&amp;R Block(HRB)</b> – H&amp;R Block beat Street forecasts for both profit and revenue in its latest quarter, and the tax preparation firm also raised its quarterly dividend by 4% to 27 cents per share. Additionally, H&amp;R Block is shifting the end of its fiscal year to June 30 from April 30, to better capture tax filing activity. H&amp;R Block shares slid 1.1% in premarket action.</p><p><blockquote><b>H&amp;R块(HRB)</b>– H&amp;R Block 最近一个季度的利润和收入都超出了华尔街的预测，这家税务准备公司还将季度股息提高了 4%，达到每股 27 美分。此外，H&amp;R Block将其财年结束日期从4月30日推迟到6月30日，以更好地捕捉报税活动。H&amp;R Block 股价在盘前交易中下跌 1.1%。</blockquote></p><p> <b>EBay(EBAY)</b> – The online marketplace operator will sell its South Korean unit to retailer Shinsegae's E-Mart unit and website operator Naver for about $3.6 billion, according to local media reports. E-Mart acknowledged the talks but said that no deal had been finalized.</p><p><blockquote><b>易趣（EBay）</b>– 据当地媒体报道，这家在线市场运营商将以约 36 亿美元的价格将其韩国子公司出售给零售商新世界旗下的 E-Mart 子公司和网站运营商 Naver。易买得承认了谈判，但表示尚未敲定交易。</blockquote></p><p> <b>General Motors(GM) </b>– GM reportedly plans to boost global spending on electric and autonomous vehicles by 30% from its most recent forecast to a total of $35 billion through 2025. People briefed on the plans told Reuters that the spending will include two additional U.S. battery plants.</p><p><blockquote><b>通用汽车(GM)</b>– 据报道，通用汽车计划到 2025 年将全球电动和自动驾驶汽车支出比最新预测增加 30%，总额达到 350 亿美元。了解该计划的人士告诉路透社，支出将包括另外两座美国电池厂。</blockquote></p><p> <b>Johnson &amp; Johnson(JNJ)</b> – The Food and Drug Administration cleared 15 million more doses of J&amp;J's Covid-19 vaccine that had been produced at a Baltimore plant run byEmergent Biosolutions(EBS). That brings the total of cleared doses to 25 million. Earlier, the FDA had rejected 60 million doses produced at that plant, saying Emergent hadn't taken proper precautions to prevent cross-contamination with another production line that was producingAstraZeneca's(AZN) Covid vaccine.</p><p><blockquote><b>强生公司(JNJ)</b>– 美国食品和药物管理局批准了另外 1500 万剂强生公司的 Covid-19 疫苗，这些疫苗是在 Mergent Biosolutions (EBS) 运营的巴尔的摩工厂生产的。这使得清除剂量总数达到 2500 万剂。早些时候，FDA拒绝了该工厂生产的6000万剂疫苗，称Emergent没有采取适当的预防措施来防止与另一条生产阿斯利康（AZN）新冠疫苗的生产线交叉污染。</blockquote></p><p> <b>Southwest Airlines(LUV) </b>– Southwest&nbsp;suffered its second computer glitch in 24 hoursTuesday, with a system outage leading to the cancellation of about 500 flights and delaying many others.</p><p><blockquote><b>西南航空(LUV)</b>– 周二，西南航空公司遭遇了 24 小时内的第二次计算机故障，系统故障导致约 500 个航班取消，许多其他航班延误。</blockquote></p><p> <b>Dish Network(DISH) </b>– The satellite TV company was upgraded to \"buy\" from \"hold\" at Pivotal Research, which cited the potential for Dish's 5G wireless network. Dish rose 1.7% in the premarket.</p><p><blockquote><b>碟形网络（DISH）</b>– Pivotal Research 将这家卫星电视公司的评级从“持有”上调至“买入”，该公司引用了 Dish 5G 无线网络的潜力。Dish 盘前上涨 1.7%。</blockquote></p><p> <b>Apollo Global(APO) </b>– Apollo sold textbook and educational technology company McGraw Hill to private-equity firm Platinum Equity for $4.5 billion.</p><p><blockquote><b>阿波罗全球（APO）</b>– Apollo 以 45 亿美元的价格将教科书和教育技术公司 McGraw Hill 出售给私募股权公司 Platinum Equity。</blockquote></p><p> <b>Regeneron(REGN) </b>– The drugmaker'sCovid-19 antibody cocktailreduced deaths in patients who could not mount their own antibody response, according to a newly published British study.</p><p><blockquote><b>再生（雨）</b>– 根据一项新发表的英国研究，该制药商的 COVID-19 抗体鸡尾酒降低了无法产生自身抗体反应的患者的死亡率。</blockquote></p><p> <b>SoFi Technologies(SOFI) </b>– The financial services platform was rated \"buy\" in new coverage at Rosenblatt Securities, noting SoFi's \"powerful\" cost advantage over legacy banks. SoFi shares rose 2.1% in the premarket.</p><p><blockquote><b>索菲科技（SOFI）</b>– 罗森布拉特证券 (Rosenblatt Securities) 在新报道中将该金融服务平台评级为“买入”，指出 SoFi 相对于传统银行具有“强大”的成本优势。SoFi 股价在盘前上涨 2.1%。</blockquote></p><p></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Toplines Before US Market Open on Wednesday<blockquote>周三美国市场开盘前的顶线</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nToplines Before US Market Open on Wednesday<blockquote>周三美国市场开盘前的顶线</blockquote>\n</h2>\n<h4 class=\"meta\">\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Tiger Newspress </p>\n<p class=\"h-time smaller\">2021-06-16 20:06</p>\n</div>\n</a>\n</h4>\n</header>\n<article>\n<p>U.S. stock index futures were mostly flat on Wednesday ahead of the&nbsp;Federal Reserve's update&nbsp;on monetary policy.</p><p><blockquote>在美联储更新货币政策之前，美国股指期货周三基本持平。</blockquote></p><p> Futures contracts tied to the Dow Jones Industrial Average were just 46 points lower. S&amp;P 500 futures were largely flat, while Nasdaq 100 futures traded up by 0.1%.</p><p><blockquote>与道琼斯工业平均指数挂钩的期货合约仅下跌 46 点。标普500期货基本持平，而纳斯达克 100 指数期货上涨 0.1%。</blockquote></p><p> <p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/33b560b1ab96b7a340369b24c17d6aa2\" tg-width=\"664\" tg-height=\"233\" referrerpolicy=\"no-referrer\"><span>*Source From Tiger Trade, EST 08:10</span></p><p><blockquote><p class=\"t-img-caption\"><span>*来源：Tiger Trade，美国东部时间 08:10</span></p></blockquote></p><p> The Fed has previously tried to assuage concerns that rising inflation would prompt it to tighten its ultra loose monetary policy, but data on Tuesday showing a jump in producer prices has again raised expectations the central bank could begin debating closing the taps at its meeting this week.</p><p><blockquote>美联储此前曾试图缓解人们对通胀上升将促使其收紧超宽松货币政策的担忧，但周二显示生产者价格上涨的数据再次引发了人们对美联储可能在本周会议上开始讨论关闭水龙头的预期。</blockquote></p><p> The central bank's latest policy statement is expected to be released with fresh economic projections at 2 p.m. ET (1800 GMT).</p><p><blockquote>央行最新的政策声明预计将于美国东部时间下午2点（格林威治标准时间1800）发布，并附有新的经济预测。</blockquote></p><p> <b>Stocks making the biggest moves in the premarket:</b></p><p><blockquote><b>盘前涨幅最大的股票：</b></blockquote></p><p> <b>Oracle(ORCL) </b>– Oracleearned $1.54 per sharefor its latest quarter, beating the consensus estimate of $1.31 a share. The business software company's revenue topped estimates as well. The company forecast current-quarter profit below consensus, however, as it increases investment in its cloud computing operations. Its shares fell 4.7% in premarket trading.</p><p><blockquote><b>甲骨文(ORCL)</b>– 甲骨文最新季度每股收益为 1.54 美元，超出市场普遍预期的每股 1.31 美元。这家商业软件公司的收入也超出了预期。然而，随着该公司增加对云计算业务的投资，该公司预计本季度利润将低于市场预期。其股价在盘前交易中下跌 4.7%。</blockquote></p><p> <b>Roblox(RBLX) </b>– Roblox tumbled 7.7% in the premarket after it reported 43 million daily active users for May, up 28% compared to a year earlier but down from 43.3 million in April. Spending by users of the videogame platform was down slightly from a year earlier.</p><p><blockquote><b>机器人（RBLX）</b>– Roblox 公布 5 月份日活跃用户为 4300 万，同比增长 28%，但低于 4 月份的 4330 万，盘前暴跌 7.7%。视频游戏平台用户的支出比去年同期略有下降。</blockquote></p><p> <b>Kindred Biosciences(KIN)</b> – The pet therapeutics company agreed to be acquired byElanco Animal Health(ELAN) for $9.25 per share, or $440 million. Kindred had closed at $6.34 Tuesday, and its stock surged 44.6% in the premarket.</p><p><blockquote><b>Kindred Biosciences</b>– 这家宠物治疗公司同意被 Elanco Animal Health (ELAN) 以每股 9.25 美元（即 4.4 亿美元）收购。Kindred 周二收于 6.34 美元，其股价在盘前飙升 44.6%。</blockquote></p><p> <b>La-Z-Boy(LZB) </b>– La-Z-Boy reported quarterly earnings of 87 cents per share, compared to a consensus estimate of 74 cents a share. The company best known for its reclining chairs also reported better-than-expected revenue. La-Z-Boy said it was being impacted by supply chain issues and significant increases in raw materials prices. Its shares lost 2.3% in the premarket.</p><p><blockquote><b>拉-Z-男孩(LZB)</b>– La-Z-Boy 公布的季度收益为每股 87 美分，而市场普遍预期为每股 74 美分。这家以躺椅而闻名的公司也公布了好于预期的收入。La-Z-Boy表示，该公司受到供应链问题和原材料价格大幅上涨的影响。其股价在盘前下跌 2.3%。</blockquote></p><p> <b>H&amp;R Block(HRB)</b> – H&amp;R Block beat Street forecasts for both profit and revenue in its latest quarter, and the tax preparation firm also raised its quarterly dividend by 4% to 27 cents per share. Additionally, H&amp;R Block is shifting the end of its fiscal year to June 30 from April 30, to better capture tax filing activity. H&amp;R Block shares slid 1.1% in premarket action.</p><p><blockquote><b>H&amp;R块(HRB)</b>– H&amp;R Block 最近一个季度的利润和收入都超出了华尔街的预测，这家税务准备公司还将季度股息提高了 4%，达到每股 27 美分。此外，H&amp;R Block将其财年结束日期从4月30日推迟到6月30日，以更好地捕捉报税活动。H&amp;R Block 股价在盘前交易中下跌 1.1%。</blockquote></p><p> <b>EBay(EBAY)</b> – The online marketplace operator will sell its South Korean unit to retailer Shinsegae's E-Mart unit and website operator Naver for about $3.6 billion, according to local media reports. E-Mart acknowledged the talks but said that no deal had been finalized.</p><p><blockquote><b>易趣（EBay）</b>– 据当地媒体报道，这家在线市场运营商将以约 36 亿美元的价格将其韩国子公司出售给零售商新世界旗下的 E-Mart 子公司和网站运营商 Naver。易买得承认了谈判，但表示尚未敲定交易。</blockquote></p><p> <b>General Motors(GM) </b>– GM reportedly plans to boost global spending on electric and autonomous vehicles by 30% from its most recent forecast to a total of $35 billion through 2025. People briefed on the plans told Reuters that the spending will include two additional U.S. battery plants.</p><p><blockquote><b>通用汽车(GM)</b>– 据报道，通用汽车计划到 2025 年将全球电动和自动驾驶汽车支出比最新预测增加 30%，总额达到 350 亿美元。了解该计划的人士告诉路透社，支出将包括另外两座美国电池厂。</blockquote></p><p> <b>Johnson &amp; Johnson(JNJ)</b> – The Food and Drug Administration cleared 15 million more doses of J&amp;J's Covid-19 vaccine that had been produced at a Baltimore plant run byEmergent Biosolutions(EBS). That brings the total of cleared doses to 25 million. Earlier, the FDA had rejected 60 million doses produced at that plant, saying Emergent hadn't taken proper precautions to prevent cross-contamination with another production line that was producingAstraZeneca's(AZN) Covid vaccine.</p><p><blockquote><b>强生公司(JNJ)</b>– 美国食品和药物管理局批准了另外 1500 万剂强生公司的 Covid-19 疫苗，这些疫苗是在 Mergent Biosolutions (EBS) 运营的巴尔的摩工厂生产的。这使得清除剂量总数达到 2500 万剂。早些时候，FDA拒绝了该工厂生产的6000万剂疫苗，称Emergent没有采取适当的预防措施来防止与另一条生产阿斯利康（AZN）新冠疫苗的生产线交叉污染。</blockquote></p><p> <b>Southwest Airlines(LUV) </b>– Southwest&nbsp;suffered its second computer glitch in 24 hoursTuesday, with a system outage leading to the cancellation of about 500 flights and delaying many others.</p><p><blockquote><b>西南航空(LUV)</b>– 周二，西南航空公司遭遇了 24 小时内的第二次计算机故障，系统故障导致约 500 个航班取消，许多其他航班延误。</blockquote></p><p> <b>Dish Network(DISH) </b>– The satellite TV company was upgraded to \"buy\" from \"hold\" at Pivotal Research, which cited the potential for Dish's 5G wireless network. Dish rose 1.7% in the premarket.</p><p><blockquote><b>碟形网络（DISH）</b>– Pivotal Research 将这家卫星电视公司的评级从“持有”上调至“买入”，该公司引用了 Dish 5G 无线网络的潜力。Dish 盘前上涨 1.7%。</blockquote></p><p> <b>Apollo Global(APO) </b>– Apollo sold textbook and educational technology company McGraw Hill to private-equity firm Platinum Equity for $4.5 billion.</p><p><blockquote><b>阿波罗全球（APO）</b>– Apollo 以 45 亿美元的价格将教科书和教育技术公司 McGraw Hill 出售给私募股权公司 Platinum Equity。</blockquote></p><p> <b>Regeneron(REGN) </b>– The drugmaker'sCovid-19 antibody cocktailreduced deaths in patients who could not mount their own antibody response, according to a newly published British study.</p><p><blockquote><b>再生（雨）</b>– 根据一项新发表的英国研究，该制药商的 COVID-19 抗体鸡尾酒降低了无法产生自身抗体反应的患者的死亡率。</blockquote></p><p> <b>SoFi Technologies(SOFI) </b>– The financial services platform was rated \"buy\" in new coverage at Rosenblatt Securities, noting SoFi's \"powerful\" cost advantage over legacy banks. SoFi shares rose 2.1% in the premarket.</p><p><blockquote><b>索菲科技（SOFI）</b>– 罗森布拉特证券 (Rosenblatt Securities) 在新报道中将该金融服务平台评级为“买入”，指出 SoFi 相对于传统银行具有“强大”的成本优势。SoFi 股价在盘前上涨 2.1%。</blockquote></p><p></p>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"ORCL":"甲骨文",".IXIC":"NASDAQ Composite",".DJI":"道琼斯",".SPX":"S&P 500 Index"},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1185341836","content_text":"U.S. stock index futures were mostly flat on Wednesday ahead of the Federal Reserve's update on monetary policy.\nFutures contracts tied to the Dow Jones Industrial Average were just 46 points lower. S&P 500 futures were largely flat, while Nasdaq 100 futures traded up by 0.1%.\n*Source From Tiger Trade, EST 08:10\nThe Fed has previously tried to assuage concerns that rising inflation would prompt it to tighten its ultra loose monetary policy, but data on Tuesday showing a jump in producer prices has again raised expectations the central bank could begin debating closing the taps at its meeting this week.\nThe central bank's latest policy statement is expected to be released with fresh economic projections at 2 p.m. ET (1800 GMT).\nStocks making the biggest moves in the premarket:\nOracle(ORCL) – Oracleearned $1.54 per sharefor its latest quarter, beating the consensus estimate of $1.31 a share. The business software company's revenue topped estimates as well. The company forecast current-quarter profit below consensus, however, as it increases investment in its cloud computing operations. Its shares fell 4.7% in premarket trading.\nRoblox(RBLX) – Roblox tumbled 7.7% in the premarket after it reported 43 million daily active users for May, up 28% compared to a year earlier but down from 43.3 million in April. Spending by users of the videogame platform was down slightly from a year earlier.\nKindred Biosciences(KIN) – The pet therapeutics company agreed to be acquired byElanco Animal Health(ELAN) for $9.25 per share, or $440 million. Kindred had closed at $6.34 Tuesday, and its stock surged 44.6% in the premarket.\nLa-Z-Boy(LZB) – La-Z-Boy reported quarterly earnings of 87 cents per share, compared to a consensus estimate of 74 cents a share. The company best known for its reclining chairs also reported better-than-expected revenue. La-Z-Boy said it was being impacted by supply chain issues and significant increases in raw materials prices. Its shares lost 2.3% in the premarket.\nH&R Block(HRB) – H&R Block beat Street forecasts for both profit and revenue in its latest quarter, and the tax preparation firm also raised its quarterly dividend by 4% to 27 cents per share. Additionally, H&R Block is shifting the end of its fiscal year to June 30 from April 30, to better capture tax filing activity. H&R Block shares slid 1.1% in premarket action.\nEBay(EBAY) – The online marketplace operator will sell its South Korean unit to retailer Shinsegae's E-Mart unit and website operator Naver for about $3.6 billion, according to local media reports. E-Mart acknowledged the talks but said that no deal had been finalized.\nGeneral Motors(GM) – GM reportedly plans to boost global spending on electric and autonomous vehicles by 30% from its most recent forecast to a total of $35 billion through 2025. People briefed on the plans told Reuters that the spending will include two additional U.S. battery plants.\nJohnson & Johnson(JNJ) – The Food and Drug Administration cleared 15 million more doses of J&J's Covid-19 vaccine that had been produced at a Baltimore plant run byEmergent Biosolutions(EBS). That brings the total of cleared doses to 25 million. Earlier, the FDA had rejected 60 million doses produced at that plant, saying Emergent hadn't taken proper precautions to prevent cross-contamination with another production line that was producingAstraZeneca's(AZN) Covid vaccine.\nSouthwest Airlines(LUV) – Southwest suffered its second computer glitch in 24 hoursTuesday, with a system outage leading to the cancellation of about 500 flights and delaying many others.\nDish Network(DISH) – The satellite TV company was upgraded to \"buy\" from \"hold\" at Pivotal Research, which cited the potential for Dish's 5G wireless network. Dish rose 1.7% in the premarket.\nApollo Global(APO) – Apollo sold textbook and educational technology company McGraw Hill to private-equity firm Platinum Equity for $4.5 billion.\nRegeneron(REGN) – The drugmaker'sCovid-19 antibody cocktailreduced deaths in patients who could not mount their own antibody response, according to a newly published British study.\nSoFi Technologies(SOFI) – The financial services platform was rated \"buy\" in new coverage at Rosenblatt Securities, noting SoFi's \"powerful\" cost advantage over legacy banks. SoFi shares rose 2.1% in the premarket.","news_type":1,"symbols_score_info":{".DJI":0.9,"ORCL":0.9,".SPX":0.9,".IXIC":0.9,"KIN":0.9}},"isVote":1,"tweetType":1,"viewCount":2291,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":182342837,"gmtCreate":1623555576529,"gmtModify":1631889099064,"author":{"id":"3582025009793897","authorId":"3582025009793897","name":"funkykoh","avatar":"https://static.tigerbbs.com/4d8ac2b302d0f306dda0b8972a050851","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3582025009793897","authorIdStr":"3582025009793897"},"themes":[],"title":"","htmlText":"But the risk is small and may have other triggering factors&nbsp;","listText":"But the risk is small and may have other triggering factors&nbsp;","text":"But the risk is small and may have other triggering factors","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":3,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/182342837","repostId":"2142206311","repostType":4,"isVote":1,"tweetType":1,"viewCount":1856,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":193090203,"gmtCreate":1620738590202,"gmtModify":1631889099065,"author":{"id":"3582025009793897","authorId":"3582025009793897","name":"funkykoh","avatar":"https://static.tigerbbs.com/4d8ac2b302d0f306dda0b8972a050851","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3582025009793897","authorIdStr":"3582025009793897"},"themes":[],"title":"","htmlText":"All crashing&nbsp;","listText":"All crashing&nbsp;","text":"All crashing","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":2,"commentSize":2,"repostSize":0,"link":"https://laohu8.com/post/193090203","repostId":"1171636052","repostType":4,"isVote":1,"tweetType":1,"viewCount":2031,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":193007811,"gmtCreate":1620738532633,"gmtModify":1631889099071,"author":{"id":"3582025009793897","authorId":"3582025009793897","name":"funkykoh","avatar":"https://static.tigerbbs.com/4d8ac2b302d0f306dda0b8972a050851","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3582025009793897","authorIdStr":"3582025009793897"},"themes":[],"title":"","htmlText":"To sell or to keep?&nbsp;","listText":"To sell or to keep?&nbsp;","text":"To sell or to keep?","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/193007811","repostId":"1101624279","repostType":4,"isVote":1,"tweetType":1,"viewCount":2040,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":371649536,"gmtCreate":1618933484625,"gmtModify":1631889099072,"author":{"id":"3582025009793897","authorId":"3582025009793897","name":"funkykoh","avatar":"https://static.tigerbbs.com/4d8ac2b302d0f306dda0b8972a050851","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3582025009793897","authorIdStr":"3582025009793897"},"themes":[],"title":"","htmlText":"Okay","listText":"Okay","text":"Okay","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/371649536","repostId":"2128841791","repostType":4,"isVote":1,"tweetType":1,"viewCount":2894,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0}],"defaultTab":"posts","isTTM":false}