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LWZ2218
LWZ2218
·
2021-12-16
Good job
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LWZ2218
LWZ2218
·
2021-12-15
Buy Buy Buy
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LWZ2218
LWZ2218
·
2021-12-14
Good time to buy Tesla stock now
Tesla Stock Is in a Bear Market Again. What’s Next for Musk’s EV Firm.<blockquote>特斯拉股票再次陷入熊市。马斯克电动汽车公司的下一步是什么。</blockquote>
Shares of electric-vehicle leader Tesla crossed into bear-market territory today. That statement is
Tesla Stock Is in a Bear Market Again. What’s Next for Musk’s EV Firm.<blockquote>特斯拉股票再次陷入熊市。马斯克电动汽车公司的下一步是什么。</blockquote>
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LWZ2218
LWZ2218
·
2021-12-13
Yes , it will reach 1580 soon
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LWZ2218
LWZ2218
·
2021-12-10
Huat
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LWZ2218
LWZ2218
·
2021-12-09
Go Go Pfizer
Pfizer Says Booster Neutralized Omicron but Variant May Elude Two Doses<blockquote>辉瑞称加强剂中和了奥密克戎病毒,但变种可能无法注射两剂</blockquote>
Pfizer Inc. PFE -0.62% and BioNTech SE BNTX -3.55% said that a third dose of their Covid-19 vaccine
Pfizer Says Booster Neutralized Omicron but Variant May Elude Two Doses<blockquote>辉瑞称加强剂中和了奥密克戎病毒,但变种可能无法注射两剂</blockquote>
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LWZ2218
LWZ2218
·
2021-12-08
Yeah dividend !!!! Buy Buy Buy
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LWZ2218
LWZ2218
·
2021-12-07
Is time to buy !!!
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LWZ2218
LWZ2218
·
2021-12-05
Is time to buy
Semiconductor stocks slid in morning trading<blockquote>半导体股早盘下跌</blockquote>
Semiconductor stocks slid in morning trading.Nvidia,TSMC,ASML and AMD fell about 2% while Marvell Te
Semiconductor stocks slid in morning trading<blockquote>半导体股早盘下跌</blockquote>
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LWZ2218
LWZ2218
·
2021-12-04
Nice
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Buy","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":3,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/607824488","repostId":"2191329909","repostType":4,"isVote":1,"tweetType":1,"viewCount":3428,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":604454369,"gmtCreate":1639441289184,"gmtModify":1639441293892,"author":{"id":"3577518888738299","authorId":"3577518888738299","name":"LWZ2218","avatar":"https://static.tigerbbs.com/f53fe88ba02bdf3f307a8e715043f7e2","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3577518888738299","idStr":"3577518888738299"},"themes":[],"htmlText":"Good time to buy Tesla stock now","listText":"Good time to buy Tesla stock now","text":"Good time to buy Tesla stock now","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":7,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/604454369","repostId":"1114636896","repostType":4,"repost":{"id":"1114636896","kind":"news","pubTimestamp":1639439509,"share":"https://www.laohu8.com/m/news/1114636896?lang=zh_CN&edition=full","pubTime":"2021-12-14 07:51","market":"us","language":"en","title":"Tesla Stock Is in a Bear Market Again. What’s Next for Musk’s EV Firm.<blockquote>特斯拉股票再次陷入熊市。马斯克电动汽车公司的下一步是什么。</blockquote>","url":"https://stock-news.laohu8.com/highlight/detail?id=1114636896","media":"Barrons","summary":"Shares of electric-vehicle leader Tesla crossed into bear-market territory today. That statement is ","content":"<p>Shares of electric-vehicle leader Tesla crossed into bear-market territory today. That statement is technically true, but also a little tiring. Stocks, individually, don’t have bear or bull markets. That terms should be reserved for, well, the overall market. Still, the big dip in a mega-cap stock is noteworthy leaving investors wondering what might come next.</p><p><blockquote>电动汽车领导者特斯拉的股价今天进入熊市区域。这种说法在技术上是正确的,但也有点累。就个人而言,股票没有熊市或牛市。这些条款应该留给整个市场。尽管如此,大型股的大幅下跌还是值得注意的,让投资者想知道接下来会发生什么。</blockquote></p><p> Tesla (ticker: TSLA) stock closed down 5% at $966.41. The S&P 500 index and Dow Jones Industrial Average both closed down 0.9%.</p><p><blockquote>特斯拉(股票代码:TSLA)股价收盘下跌5%,至966.41美元。标普500指数和道琼斯工业平均指数均收跌0.9%。</blockquote></p><p> The Monday dip sent the company’s market cap below $1 trillion based on the number of shares outstanding, excluding management stock options. Shares are down 21% from the Nov. 4 closing high of $1,229.91. Shares are down 22% from the intraday high of $1,243.49.</p><p><blockquote>根据已发行股票数量(不包括管理层股票期权)计算,周一的下跌使该公司的市值跌破1万亿美元。股价较11月4日收盘高点1,229.91美元下跌21%。股价较盘中高点1,243.49美元下跌22%。</blockquote></p><p> Whether or not bear markets should be measured from a closing high or an intraday high is the source of debate on Wall Street. But again, the debate doesn’t really matter in this instance because individual stocks don’t have bull and bear markets.</p><p><blockquote>熊市应该从收盘高点还是盘中高点来衡量是华尔街争论的焦点。但同样,在这种情况下,争论并不重要,因为个股没有牛市和熊市。</blockquote></p><p> Whether it’s a bear market or not isn’t the point for individual investors. The pain of a 20% drop is real.</p><p><blockquote>对于个人投资者来说,是否是熊市并不是重点。下跌20%的痛苦是真实的。</blockquote></p><p> One of the last times Tesla stock closed in bear-market territory was February 2021. (Yes, <i>Barron’s</i> wrote about the single stock bear market then, too.) Back then, interest rates were rising and highly valued tech stocks took it on the chin. Higher rates hurt the valuation of shares of faster-growing companies more than those of slow-growing mature companies—that’s just the way the math of higher interest rates works out.</p><p><blockquote>特斯拉股票最后一次收于熊市区域是在2021年2月。(是的,<i>巴伦周刊</i>当时也写过关于单股熊市的文章。)当时,利率正在上升,高估值的科技股承受了压力。较高的利率对增长较快的公司股票估值的损害大于增长缓慢的成熟公司的股票估值——这正是较高利率的数学计算方式。</blockquote></p><p> Back then it took about six months for the stock to retake its old highs. If that were to happen again, bullish investors would be waiting until June 2022 to see Tesla stock hit $1,300.</p><p><blockquote>当时,该股花了大约六个月的时间才恢复到旧高点。如果这种情况再次发生,看涨的投资者将等到2022年6月才能看到特斯拉股价触及1,300美元。</blockquote></p><p> That would be a long wait for bulls, and while there is no way to know if that scenario will even unfold, there is a lot going on that could move the stock in the coming couple of months. Bullish and bearish Tesla investors will be watching for the startup of two new plants in Germany and Texas, the impact of those new plants on profit margins, the start of deliveries of the Tesla Cybertruck and the overall growth of EVs in the U.S., Europe, and China.</p><p><blockquote>对于多头来说,这将是一个漫长的等待,虽然没有办法知道这种情况是否会发生,但未来几个月有很多事情可能会影响该股。看涨和看跌的特斯拉投资者将关注德国和德克萨斯两家新工厂的启动、这些新工厂对利润率的影响、特斯拉Cybertruck的开始交付以及美国电动汽车的整体增长、欧洲和中国。</blockquote></p><p> With all that coming, it raising the question of why the shares are struggling.</p><p><blockquote>随之而来的是,这引发了一个问题:为什么股价陷入困境。</blockquote></p><p> Two things might be at work. First, CEO Elon Musk is still selling stock. It creates an overhang. Some bulls might wait to buy until the large sales are over. Musk has at least 5 million or 6 million shares left to sell associated with his expiring stock options. He will probably be done selling by the end of 2021, but he might just Tweet out when he’s done. At current pace, we figure by year-end.</p><p><blockquote>可能有两件事在起作用。首先,首席执行官埃隆·马斯克仍在出售股票。它创造了一个悬垂。一些多头可能会等到大规模抛售结束后再买入。马斯克还有至少500万或600万股与他即将到期的股票期权相关的股票可供出售。他可能会在2021年底完成出售,但他可能会在完成后发布推文。按照目前的速度,我们预计到年底。</blockquote></p><p> Second, there is the issue of Musk being named Time’s Person of the Year.Amazon.com (AMZN) founder Jeff Bezos won that distinction in 1999, near a multiyear peak in that stock. Amazon shares went on to slide, and some investors think Tesla stock could do the same.</p><p><blockquote>其次,还有马斯克被《时代》杂志评为年度人物的问题。亚马逊。com(AMZN)创始人杰夫·贝索斯(Mark Zuckerberg)在1999年获得了这一殊荣,当时该股股价接近多年来的峰值。亚马逊股价继续下滑,一些投资者认为特斯拉股价也可能出现同样的情况。</blockquote></p><p> The Amazon comparison with Tesla doesn’t quite match up, however. The two companies are at very different stages of development when their top executives won Time’s distinction. Amazon had a market capitalization of $27 billion back then. Tesla’s market cap is now hovering around $1 trillion.</p><p><blockquote>然而,亚马逊与特斯拉的比较并不完全匹配。当这两家公司的高管赢得《时代》杂志的殊荣时,它们正处于截然不同的发展阶段。亚马逊当时的市值为270亿美元。特斯拉的市值目前徘徊在1万亿美元左右。</blockquote></p><p> Still, it’s a belief, and traders do odd things from time to time, justified or not. When stocks move upward, or downward, momentum traders will jump on the trend for whatever reason.</p><p><blockquote>尽管如此,这仍然是一种信念,交易者时不时会做一些奇怪的事情,无论是否合理。当股票上涨或下跌时,无论出于何种原因,动量交易者都会顺势而为。</blockquote></p><p></p>","source":"lsy1601382232898","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Tesla Stock Is in a Bear Market Again. What’s Next for Musk’s EV Firm.<blockquote>特斯拉股票再次陷入熊市。马斯克电动汽车公司的下一步是什么。</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nTesla Stock Is in a Bear Market Again. What’s Next for Musk’s EV Firm.<blockquote>特斯拉股票再次陷入熊市。马斯克电动汽车公司的下一步是什么。</blockquote>\n</h2>\n<h4 class=\"meta\">\n<p class=\"head\">\n<strong class=\"h-name small\">Barrons</strong><span class=\"h-time small\">2021-12-14 07:51</span>\n</p>\n</h4>\n</header>\n<article>\n<p>Shares of electric-vehicle leader Tesla crossed into bear-market territory today. That statement is technically true, but also a little tiring. Stocks, individually, don’t have bear or bull markets. That terms should be reserved for, well, the overall market. Still, the big dip in a mega-cap stock is noteworthy leaving investors wondering what might come next.</p><p><blockquote>电动汽车领导者特斯拉的股价今天进入熊市区域。这种说法在技术上是正确的,但也有点累。就个人而言,股票没有熊市或牛市。这些条款应该留给整个市场。尽管如此,大型股的大幅下跌还是值得注意的,让投资者想知道接下来会发生什么。</blockquote></p><p> Tesla (ticker: TSLA) stock closed down 5% at $966.41. The S&P 500 index and Dow Jones Industrial Average both closed down 0.9%.</p><p><blockquote>特斯拉(股票代码:TSLA)股价收盘下跌5%,至966.41美元。标普500指数和道琼斯工业平均指数均收跌0.9%。</blockquote></p><p> The Monday dip sent the company’s market cap below $1 trillion based on the number of shares outstanding, excluding management stock options. Shares are down 21% from the Nov. 4 closing high of $1,229.91. Shares are down 22% from the intraday high of $1,243.49.</p><p><blockquote>根据已发行股票数量(不包括管理层股票期权)计算,周一的下跌使该公司的市值跌破1万亿美元。股价较11月4日收盘高点1,229.91美元下跌21%。股价较盘中高点1,243.49美元下跌22%。</blockquote></p><p> Whether or not bear markets should be measured from a closing high or an intraday high is the source of debate on Wall Street. But again, the debate doesn’t really matter in this instance because individual stocks don’t have bull and bear markets.</p><p><blockquote>熊市应该从收盘高点还是盘中高点来衡量是华尔街争论的焦点。但同样,在这种情况下,争论并不重要,因为个股没有牛市和熊市。</blockquote></p><p> Whether it’s a bear market or not isn’t the point for individual investors. The pain of a 20% drop is real.</p><p><blockquote>对于个人投资者来说,是否是熊市并不是重点。下跌20%的痛苦是真实的。</blockquote></p><p> One of the last times Tesla stock closed in bear-market territory was February 2021. (Yes, <i>Barron’s</i> wrote about the single stock bear market then, too.) Back then, interest rates were rising and highly valued tech stocks took it on the chin. Higher rates hurt the valuation of shares of faster-growing companies more than those of slow-growing mature companies—that’s just the way the math of higher interest rates works out.</p><p><blockquote>特斯拉股票最后一次收于熊市区域是在2021年2月。(是的,<i>巴伦周刊</i>当时也写过关于单股熊市的文章。)当时,利率正在上升,高估值的科技股承受了压力。较高的利率对增长较快的公司股票估值的损害大于增长缓慢的成熟公司的股票估值——这正是较高利率的数学计算方式。</blockquote></p><p> Back then it took about six months for the stock to retake its old highs. If that were to happen again, bullish investors would be waiting until June 2022 to see Tesla stock hit $1,300.</p><p><blockquote>当时,该股花了大约六个月的时间才恢复到旧高点。如果这种情况再次发生,看涨的投资者将等到2022年6月才能看到特斯拉股价触及1,300美元。</blockquote></p><p> That would be a long wait for bulls, and while there is no way to know if that scenario will even unfold, there is a lot going on that could move the stock in the coming couple of months. Bullish and bearish Tesla investors will be watching for the startup of two new plants in Germany and Texas, the impact of those new plants on profit margins, the start of deliveries of the Tesla Cybertruck and the overall growth of EVs in the U.S., Europe, and China.</p><p><blockquote>对于多头来说,这将是一个漫长的等待,虽然没有办法知道这种情况是否会发生,但未来几个月有很多事情可能会影响该股。看涨和看跌的特斯拉投资者将关注德国和德克萨斯两家新工厂的启动、这些新工厂对利润率的影响、特斯拉Cybertruck的开始交付以及美国电动汽车的整体增长、欧洲和中国。</blockquote></p><p> With all that coming, it raising the question of why the shares are struggling.</p><p><blockquote>随之而来的是,这引发了一个问题:为什么股价陷入困境。</blockquote></p><p> Two things might be at work. First, CEO Elon Musk is still selling stock. It creates an overhang. Some bulls might wait to buy until the large sales are over. Musk has at least 5 million or 6 million shares left to sell associated with his expiring stock options. He will probably be done selling by the end of 2021, but he might just Tweet out when he’s done. At current pace, we figure by year-end.</p><p><blockquote>可能有两件事在起作用。首先,首席执行官埃隆·马斯克仍在出售股票。它创造了一个悬垂。一些多头可能会等到大规模抛售结束后再买入。马斯克还有至少500万或600万股与他即将到期的股票期权相关的股票可供出售。他可能会在2021年底完成出售,但他可能会在完成后发布推文。按照目前的速度,我们预计到年底。</blockquote></p><p> Second, there is the issue of Musk being named Time’s Person of the Year.Amazon.com (AMZN) founder Jeff Bezos won that distinction in 1999, near a multiyear peak in that stock. Amazon shares went on to slide, and some investors think Tesla stock could do the same.</p><p><blockquote>其次,还有马斯克被《时代》杂志评为年度人物的问题。亚马逊。com(AMZN)创始人杰夫·贝索斯(Mark Zuckerberg)在1999年获得了这一殊荣,当时该股股价接近多年来的峰值。亚马逊股价继续下滑,一些投资者认为特斯拉股价也可能出现同样的情况。</blockquote></p><p> The Amazon comparison with Tesla doesn’t quite match up, however. The two companies are at very different stages of development when their top executives won Time’s distinction. Amazon had a market capitalization of $27 billion back then. Tesla’s market cap is now hovering around $1 trillion.</p><p><blockquote>然而,亚马逊与特斯拉的比较并不完全匹配。当这两家公司的高管赢得《时代》杂志的殊荣时,它们正处于截然不同的发展阶段。亚马逊当时的市值为270亿美元。特斯拉的市值目前徘徊在1万亿美元左右。</blockquote></p><p> Still, it’s a belief, and traders do odd things from time to time, justified or not. When stocks move upward, or downward, momentum traders will jump on the trend for whatever reason.</p><p><blockquote>尽管如此,这仍然是一种信念,交易者时不时会做一些奇怪的事情,无论是否合理。当股票上涨或下跌时,无论出于何种原因,动量交易者都会顺势而为。</blockquote></p><p></p>\n<div class=\"bt-text\">\n\n\n<p> 来源:<a href=\"https://www.barrons.com/articles/tesla-stock-bear-musk-51639436863?mod=hp_LATEST\">Barrons</a></p>\n<p>为提升您的阅读体验,我们对本页面进行了排版优化</p>\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"TSLA":"特斯拉"},"source_url":"https://www.barrons.com/articles/tesla-stock-bear-musk-51639436863?mod=hp_LATEST","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1114636896","content_text":"Shares of electric-vehicle leader Tesla crossed into bear-market territory today. That statement is technically true, but also a little tiring. Stocks, individually, don’t have bear or bull markets. That terms should be reserved for, well, the overall market. Still, the big dip in a mega-cap stock is noteworthy leaving investors wondering what might come next.\nTesla (ticker: TSLA) stock closed down 5% at $966.41. The S&P 500 index and Dow Jones Industrial Average both closed down 0.9%.\nThe Monday dip sent the company’s market cap below $1 trillion based on the number of shares outstanding, excluding management stock options. Shares are down 21% from the Nov. 4 closing high of $1,229.91. Shares are down 22% from the intraday high of $1,243.49.\nWhether or not bear markets should be measured from a closing high or an intraday high is the source of debate on Wall Street. But again, the debate doesn’t really matter in this instance because individual stocks don’t have bull and bear markets.\nWhether it’s a bear market or not isn’t the point for individual investors. The pain of a 20% drop is real.\nOne of the last times Tesla stock closed in bear-market territory was February 2021. (Yes, Barron’s wrote about the single stock bear market then, too.) Back then, interest rates were rising and highly valued tech stocks took it on the chin. Higher rates hurt the valuation of shares of faster-growing companies more than those of slow-growing mature companies—that’s just the way the math of higher interest rates works out.\nBack then it took about six months for the stock to retake its old highs. If that were to happen again, bullish investors would be waiting until June 2022 to see Tesla stock hit $1,300.\nThat would be a long wait for bulls, and while there is no way to know if that scenario will even unfold, there is a lot going on that could move the stock in the coming couple of months. Bullish and bearish Tesla investors will be watching for the startup of two new plants in Germany and Texas, the impact of those new plants on profit margins, the start of deliveries of the Tesla Cybertruck and the overall growth of EVs in the U.S., Europe, and China.\nWith all that coming, it raising the question of why the shares are struggling.\nTwo things might be at work. First, CEO Elon Musk is still selling stock. It creates an overhang. Some bulls might wait to buy until the large sales are over. Musk has at least 5 million or 6 million shares left to sell associated with his expiring stock options. He will probably be done selling by the end of 2021, but he might just Tweet out when he’s done. At current pace, we figure by year-end.\nSecond, there is the issue of Musk being named Time’s Person of the Year.Amazon.com (AMZN) founder Jeff Bezos won that distinction in 1999, near a multiyear peak in that stock. Amazon shares went on to slide, and some investors think Tesla stock could do the same.\nThe Amazon comparison with Tesla doesn’t quite match up, however. The two companies are at very different stages of development when their top executives won Time’s distinction. Amazon had a market capitalization of $27 billion back then. Tesla’s market cap is now hovering around $1 trillion.\nStill, it’s a belief, and traders do odd things from time to time, justified or not. When stocks move upward, or downward, momentum traders will jump on the trend for whatever reason.","news_type":1,"symbols_score_info":{"TSLA":0.9}},"isVote":1,"tweetType":1,"viewCount":3744,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":604355502,"gmtCreate":1639354250507,"gmtModify":1639354254429,"author":{"id":"3577518888738299","authorId":"3577518888738299","name":"LWZ2218","avatar":"https://static.tigerbbs.com/f53fe88ba02bdf3f307a8e715043f7e2","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3577518888738299","idStr":"3577518888738299"},"themes":[],"htmlText":"Yes , it will reach 1580 soon","listText":"Yes , it will reach 1580 soon","text":"Yes , it will reach 1580 soon","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":11,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/604355502","repostId":"2190677202","repostType":4,"isVote":1,"tweetType":1,"viewCount":2508,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":605062446,"gmtCreate":1639094436791,"gmtModify":1639094437052,"author":{"id":"3577518888738299","authorId":"3577518888738299","name":"LWZ2218","avatar":"https://static.tigerbbs.com/f53fe88ba02bdf3f307a8e715043f7e2","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3577518888738299","idStr":"3577518888738299"},"themes":[],"htmlText":"Huat ","listText":"Huat ","text":"Huat","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/605062446","repostId":"2190964556","repostType":4,"isVote":1,"tweetType":1,"viewCount":3679,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":602829454,"gmtCreate":1639008282743,"gmtModify":1639008282960,"author":{"id":"3577518888738299","authorId":"3577518888738299","name":"LWZ2218","avatar":"https://static.tigerbbs.com/f53fe88ba02bdf3f307a8e715043f7e2","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3577518888738299","idStr":"3577518888738299"},"themes":[],"htmlText":"Go Go Pfizer","listText":"Go Go Pfizer","text":"Go Go Pfizer","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":8,"commentSize":2,"repostSize":0,"link":"https://laohu8.com/post/602829454","repostId":"1141815911","repostType":4,"repost":{"id":"1141815911","kind":"news","pubTimestamp":1639007843,"share":"https://www.laohu8.com/m/news/1141815911?lang=zh_CN&edition=full","pubTime":"2021-12-09 07:57","market":"us","language":"en","title":"Pfizer Says Booster Neutralized Omicron but Variant May Elude Two Doses<blockquote>辉瑞称加强剂中和了奥密克戎病毒,但变种可能无法注射两剂</blockquote>","url":"https://stock-news.laohu8.com/highlight/detail?id=1141815911","media":"The Wall Street Journal","summary":"Pfizer Inc. PFE -0.62% and BioNTech SE BNTX -3.55% said that a third dose of their Covid-19 vaccine ","content":"<p>Pfizer Inc. PFE -0.62% and BioNTech SE BNTX -3.55% said that a third dose of their Covid-19 vaccine neutralized the Omicron variant in lab tests but that the two-dose regimen was significantly less effective at blocking the virus.</p><p><blockquote>辉瑞公司PFE-0.62%和BioNTech SE BNTX-3.55%表示,他们的第三剂Covid-19疫苗在实验室测试中中和了奥密克戎变种,但两剂方案在阻断病毒方面的效果明显较差。</blockquote></p><p> A third dose increased antibodies 25-fold compared with two doses against the Omicron variant, the companies said. Still, two doses may prove effective in preventing severe illness from Covid-19, they said, because immune cells are able to recognize 80% of parts of the spike protein that the vaccine targets.</p><p><blockquote>两家公司表示,与针对奥密克戎变种的两剂相比,第三剂使抗体增加了25倍。他们说,尽管如此,两剂疫苗可能会有效预防Covid-19引起的严重疾病,因为免疫细胞能够识别疫苗靶向的刺突蛋白的80%部分。</blockquote></p><p> The results were issued in a press release by the companies, and weren’t peer reviewed and published in a scientific journal.</p><p><blockquote>这些结果是在两家公司的新闻稿中发布的,没有经过同行评审也没有发表在科学期刊上。</blockquote></p><p> The findings from the companies’ early study, and one by scientists in South Africa, suggest that three doses will be needed to produce a similar immune response against Omicron as was provided by just two doses in earlier strains of the virus.</p><p><blockquote>两家公司的早期研究结果以及南非科学家的一项研究结果表明,需要三剂疫苗才能产生与早期病毒株仅两剂疫苗类似的针对奥密克戎病毒的免疫反应。</blockquote></p><p> It also bolsters the case for repeated and periodic boosters to maintain people’s immune defenses against an evolving Covid-19, the companies said.</p><p><blockquote>两家公司表示,这也支持了重复和定期加强剂以维持人们对不断发展的Covid-19的免疫防御的理由。</blockquote></p><p> “This is very positive news that should make everyone even more motivated to get vaccinated” and get a booster, said Pfizer Chief Scientific Officer Mikael Dolsten.</p><p><blockquote>辉瑞首席科学官米凯尔·多尔斯滕(Mikael Dolsten)表示,“这是一个非常积极的消息,应该会让每个人都更有动力接种疫苗”并接种加强剂。</blockquote></p><p> The companies’ current vaccine will provide a strong defense against Omicron, especially if people get a booster shot, Dr. Dolsten said. The three-dose regimen, he added, could provide stopgap protection against Omicron through the winter and until a new vaccine targeted directly at the variant would be ready if needed.</p><p><blockquote>多尔斯滕博士说,两家公司目前的疫苗将为奥密克戎提供强有力的防御,特别是如果人们接受加强注射的话。他补充说,三剂方案可以在整个冬季提供针对奥密克戎病毒的权宜之计,直到需要时直接针对该变种的新疫苗准备就绪。</blockquote></p><p> Pfizer and BioNTech are working on an Omicron-specific vaccine that they hope to have available by March 2022 if the variant becomes widespread by then. Researchers started working on the new vaccine on Thanksgiving Day, Nov. 25, shortly after Omicron was identified.</p><p><blockquote>辉瑞和BioNTech正在研究一种针对奥密克戎病毒的疫苗,如果该变种到那时变得广泛传播,他们希望在2022年3月之前上市。奥密克戎病毒被发现后不久,研究人员于11月25日感恩节开始研究这种新疫苗。</blockquote></p><p> The vaccine trains the immune system to fight the virus by generating immune-system soldiers known as antibodies, which attach to the virus and prevent it from replicating in healthy cells. The vaccine also produces other immune-system fighters called T cells that can kick in after infection to help target and clear the virus, preventing more serious disease.</p><p><blockquote>该疫苗通过产生称为抗体的免疫系统士兵来训练免疫系统对抗病毒,抗体附着在病毒上并阻止其在健康细胞中复制。该疫苗还产生其他称为T细胞的免疫系统战士,可以在感染后发挥作用,帮助靶向和清除病毒,预防更严重的疾病。</blockquote></p><p> Pfizer and BioNTech said that Omicron still appears susceptible to T cells produced by the vaccine.</p><p><blockquote>辉瑞和BioNTech表示,奥密克戎似乎仍然容易受到疫苗产生的T细胞的影响。</blockquote></p><p> Dr. Dolsten estimated there is a greater than 50% chance that Omicron becomes the dominant strain spreading in the U.S. by the spring, though it is too soon to know with certainty, he said.</p><p><blockquote>多尔斯滕博士估计,到春季,奥密克戎病毒成为美国传播的主要毒株的可能性超过50%,但现在确定还为时过早。</blockquote></p><p> The preliminary lab data comes from an analysis of blood samples from vaccinated patients measuring antibodies capable of neutralizing the virus causing Covid-19, including the Omicron variant. Blood samples were collected three weeks after patients received their second dose, or one month after receiving their third dose.</p><p><blockquote>初步实验室数据来自对接种疫苗患者血液样本的分析,测量能够中和导致Covid-19的病毒(包括奥密克戎变种)的抗体。在患者接受第二剂后三周或接受第三剂后一个月采集血样。</blockquote></p><p> The number of antibodies generated by a third booster shot against Omicron is similar to two doses against an older strain of the virus, the companies said.</p><p><blockquote>两家公司表示,针对奥密克戎病毒的第三次加强注射产生的抗体数量与针对旧病毒株的两次注射相似。</blockquote></p><p> “These preliminary data appear to show the Pfizer vaccine does in fact protect against Omicron, and that’s very good news,” said Philip Landrigan, director of Boston College’s Global Public Health and the Global Common Good program.</p><p><blockquote>“这些初步数据似乎表明辉瑞疫苗确实可以预防奥密克戎病毒,这是一个非常好的消息,”Boston College全球公共卫生和全球公益项目主任Philip Landrigan说。</blockquote></p><p> Monica Gandhi, a professor of medicine at the University of California, San Francisco, said the results suggested two doses will protect many people from getting bad cases leading to hospitalization or death.</p><p><blockquote>加州大学旧金山分校医学教授莫妮卡·甘地表示,结果表明,两剂疫苗将保护许多人免受导致住院或死亡的严重病例。</blockquote></p><p> “Two doses are still effective against severe disease, whether people get boosters or not,” said Dr. Gandhi, who is recommending boosters for high-risk patients, including those with HIV. “For people who are at high risk of severe disease, it’s so important to get them boosted, but I don’t think it’s mandatory for young healthy people.”</p><p><blockquote>甘地博士说:“无论人们是否接种加强剂,两剂疫苗对严重疾病仍然有效。”他建议为包括艾滋病毒感染者在内的高危患者接种加强剂。“对于患有严重疾病的高风险人群来说,给他们注射疫苗非常重要,但我认为这对于年轻的健康人来说并不是强制性的。”</blockquote></p><p> The company’s early findings come a day after scientists in South Africa reported findings from early lab tests indicating a 41-fold reduction in the Pfizer-BioNTech vaccine’s neutralization of Omicron than the original version of the virus.</p><p><blockquote>该公司的早期发现发布前一天,南非科学家报告了早期实验室测试的结果,表明辉瑞-BioNTech疫苗对奥密克戎病毒的中和作用比原始版本的病毒降低了41倍。</blockquote></p><p> The researchers, however, found greater antibody responses against Omicron in blood taken from subjects who were fully vaccinated and had previously been infected with Covid-19.</p><p><blockquote>然而,研究人员发现,从完全接种疫苗且之前感染过Covid-19的受试者身上采集的血液中,针对奥密克戎病毒的抗体反应更强。</blockquote></p><p> The companies will continue to work on a variant vaccine despite the promising signs that boosting with the original shot offers good protection against Omicron, said BioNTech Chief Executive Uğur Şahin. That is because they would need to see more data on how their vaccine holds up against the new variant, including real-world effectiveness data, expected in the coming weeks.</p><p><blockquote>BioNTech首席执行官Uğur Ş ahin表示,尽管有令人鼓舞的迹象表明,使用原始疫苗加强注射可以很好地预防奥密克戎病,但两家公司仍将继续研究变异疫苗。这是因为他们需要看到更多关于他们的疫苗如何抵抗新变种的数据,包括预计在未来几周内的真实世界有效性数据。</blockquote></p><p> “Only in combination will we understand the relevance of this data and potential protection against Omicron-mediated disease and severe disease,” he said.</p><p><blockquote>他说:“只有结合起来,我们才能了解这些数据的相关性以及对奥密克戎病介导的疾病和严重疾病的潜在保护作用。”</blockquote></p><p> Real-world data on vaccine effectiveness against Omicron won’t be available for at least six weeks, Dr. Şahin said, because the case numbers need to be higher before this can be measured.</p><p><blockquote>Ş ahin博士说,有关奥密克戎疫苗有效性的真实数据至少在六周内无法获得,因为病例数需要更高才能衡量。</blockquote></p><p></p><p> Meanwhile, the companies are moving forward with manufacturing an Omicron-specific vaccine. The first doses, for experimental use, will be ready in January, BioNTech executives said.</p><p><blockquote>与此同时,两家公司正在推进奥密克戎专用疫苗的生产。BioNTech高管表示,用于实验用途的第一剂疫苗将于1月份准备就绪。</blockquote></p><p> Omicron was first identified by scientists in South Africa last month. Since then the World Health Organization has deemed it a variant of concern. And it has since been detected around the world, including in the U.S.</p><p><blockquote>上个月,科学家首次在南非发现了奥密克戎病毒。从那时起,世界卫生组织就认为这是一个值得关注的变种。此后,包括美国在内的世界各地都发现了这种病毒。</blockquote></p><p> Researchers have been trying to understand how contagious the new strain is, as well as how well it might be able to evade Covid-19 vaccines and whether it causes severe disease. Some preliminary reports suggest the variant is more contagious but might cause milder disease, though researchers say it is too early to know.</p><p><blockquote>研究人员一直在试图了解这种新毒株的传染性如何,以及它逃避Covid-19疫苗的能力如何,以及它是否会导致严重疾病。一些初步报告表明,这种变异更具传染性,但可能会导致较轻的疾病,尽管研究人员表示现在知道还为时过早。</blockquote></p><p> Pfizer and BioNTech said they expect to make four billion vaccine doses next year, even if an Omicron-specific vaccine is required by then.</p><p><blockquote>辉瑞和BioNTech表示,他们预计明年将生产40亿剂疫苗,即使届时需要奥密克戎专用疫苗。</blockquote></p><p> Dr. Dolsten said that regardless of how widespread Omicron becomes, continued booster shots will likely be needed going forward to provide protection against Covid-19. A fourth booster dose is likely to be needed in the spring or fall of 2022, he said.</p><p><blockquote>多尔斯滕博士说,无论奥密克戎病变得多么普遍,未来可能需要持续的加强注射来提供针对新冠肺炎的保护。他说,2022年春季或秋季可能需要第四次加强剂量。</blockquote></p><p> “It’s increasingly clear you need to have a long-term perspective, with continued boosting to have strong durable immunity,” said Dr. Dolsten. “If the landscape looks similar to today, we will likely continue to boost with the current vaccine.”</p><p><blockquote>多尔斯滕博士说:“越来越明显的是,你需要有长远的眼光,持续增强才能拥有强大持久的免疫力。”“如果情况看起来与今天相似,我们可能会继续使用当前的疫苗加强疫苗。”</blockquote></p><p> Pfizer’s shares rose 1% while BioNTech’s American depositary shares fell 0.2% in morning trading.</p><p><blockquote>辉瑞股价上涨1%,而BioNTech美国存托股早盘下跌0.2%。</blockquote></p><p></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Pfizer Says Booster Neutralized Omicron but Variant May Elude Two Doses<blockquote>辉瑞称加强剂中和了奥密克戎病毒,但变种可能无法注射两剂</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nPfizer Says Booster Neutralized Omicron but Variant May Elude Two Doses<blockquote>辉瑞称加强剂中和了奥密克戎病毒,但变种可能无法注射两剂</blockquote>\n</h2>\n<h4 class=\"meta\">\n<p class=\"head\">\n<strong class=\"h-name small\">The Wall Street Journal</strong><span class=\"h-time small\">2021-12-09 07:57</span>\n</p>\n</h4>\n</header>\n<article>\n<p>Pfizer Inc. PFE -0.62% and BioNTech SE BNTX -3.55% said that a third dose of their Covid-19 vaccine neutralized the Omicron variant in lab tests but that the two-dose regimen was significantly less effective at blocking the virus.</p><p><blockquote>辉瑞公司PFE-0.62%和BioNTech SE BNTX-3.55%表示,他们的第三剂Covid-19疫苗在实验室测试中中和了奥密克戎变种,但两剂方案在阻断病毒方面的效果明显较差。</blockquote></p><p> A third dose increased antibodies 25-fold compared with two doses against the Omicron variant, the companies said. Still, two doses may prove effective in preventing severe illness from Covid-19, they said, because immune cells are able to recognize 80% of parts of the spike protein that the vaccine targets.</p><p><blockquote>两家公司表示,与针对奥密克戎变种的两剂相比,第三剂使抗体增加了25倍。他们说,尽管如此,两剂疫苗可能会有效预防Covid-19引起的严重疾病,因为免疫细胞能够识别疫苗靶向的刺突蛋白的80%部分。</blockquote></p><p> The results were issued in a press release by the companies, and weren’t peer reviewed and published in a scientific journal.</p><p><blockquote>这些结果是在两家公司的新闻稿中发布的,没有经过同行评审也没有发表在科学期刊上。</blockquote></p><p> The findings from the companies’ early study, and one by scientists in South Africa, suggest that three doses will be needed to produce a similar immune response against Omicron as was provided by just two doses in earlier strains of the virus.</p><p><blockquote>两家公司的早期研究结果以及南非科学家的一项研究结果表明,需要三剂疫苗才能产生与早期病毒株仅两剂疫苗类似的针对奥密克戎病毒的免疫反应。</blockquote></p><p> It also bolsters the case for repeated and periodic boosters to maintain people’s immune defenses against an evolving Covid-19, the companies said.</p><p><blockquote>两家公司表示,这也支持了重复和定期加强剂以维持人们对不断发展的Covid-19的免疫防御的理由。</blockquote></p><p> “This is very positive news that should make everyone even more motivated to get vaccinated” and get a booster, said Pfizer Chief Scientific Officer Mikael Dolsten.</p><p><blockquote>辉瑞首席科学官米凯尔·多尔斯滕(Mikael Dolsten)表示,“这是一个非常积极的消息,应该会让每个人都更有动力接种疫苗”并接种加强剂。</blockquote></p><p> The companies’ current vaccine will provide a strong defense against Omicron, especially if people get a booster shot, Dr. Dolsten said. The three-dose regimen, he added, could provide stopgap protection against Omicron through the winter and until a new vaccine targeted directly at the variant would be ready if needed.</p><p><blockquote>多尔斯滕博士说,两家公司目前的疫苗将为奥密克戎提供强有力的防御,特别是如果人们接受加强注射的话。他补充说,三剂方案可以在整个冬季提供针对奥密克戎病毒的权宜之计,直到需要时直接针对该变种的新疫苗准备就绪。</blockquote></p><p> Pfizer and BioNTech are working on an Omicron-specific vaccine that they hope to have available by March 2022 if the variant becomes widespread by then. Researchers started working on the new vaccine on Thanksgiving Day, Nov. 25, shortly after Omicron was identified.</p><p><blockquote>辉瑞和BioNTech正在研究一种针对奥密克戎病毒的疫苗,如果该变种到那时变得广泛传播,他们希望在2022年3月之前上市。奥密克戎病毒被发现后不久,研究人员于11月25日感恩节开始研究这种新疫苗。</blockquote></p><p> The vaccine trains the immune system to fight the virus by generating immune-system soldiers known as antibodies, which attach to the virus and prevent it from replicating in healthy cells. The vaccine also produces other immune-system fighters called T cells that can kick in after infection to help target and clear the virus, preventing more serious disease.</p><p><blockquote>该疫苗通过产生称为抗体的免疫系统士兵来训练免疫系统对抗病毒,抗体附着在病毒上并阻止其在健康细胞中复制。该疫苗还产生其他称为T细胞的免疫系统战士,可以在感染后发挥作用,帮助靶向和清除病毒,预防更严重的疾病。</blockquote></p><p> Pfizer and BioNTech said that Omicron still appears susceptible to T cells produced by the vaccine.</p><p><blockquote>辉瑞和BioNTech表示,奥密克戎似乎仍然容易受到疫苗产生的T细胞的影响。</blockquote></p><p> Dr. Dolsten estimated there is a greater than 50% chance that Omicron becomes the dominant strain spreading in the U.S. by the spring, though it is too soon to know with certainty, he said.</p><p><blockquote>多尔斯滕博士估计,到春季,奥密克戎病毒成为美国传播的主要毒株的可能性超过50%,但现在确定还为时过早。</blockquote></p><p> The preliminary lab data comes from an analysis of blood samples from vaccinated patients measuring antibodies capable of neutralizing the virus causing Covid-19, including the Omicron variant. Blood samples were collected three weeks after patients received their second dose, or one month after receiving their third dose.</p><p><blockquote>初步实验室数据来自对接种疫苗患者血液样本的分析,测量能够中和导致Covid-19的病毒(包括奥密克戎变种)的抗体。在患者接受第二剂后三周或接受第三剂后一个月采集血样。</blockquote></p><p> The number of antibodies generated by a third booster shot against Omicron is similar to two doses against an older strain of the virus, the companies said.</p><p><blockquote>两家公司表示,针对奥密克戎病毒的第三次加强注射产生的抗体数量与针对旧病毒株的两次注射相似。</blockquote></p><p> “These preliminary data appear to show the Pfizer vaccine does in fact protect against Omicron, and that’s very good news,” said Philip Landrigan, director of Boston College’s Global Public Health and the Global Common Good program.</p><p><blockquote>“这些初步数据似乎表明辉瑞疫苗确实可以预防奥密克戎病毒,这是一个非常好的消息,”Boston College全球公共卫生和全球公益项目主任Philip Landrigan说。</blockquote></p><p> Monica Gandhi, a professor of medicine at the University of California, San Francisco, said the results suggested two doses will protect many people from getting bad cases leading to hospitalization or death.</p><p><blockquote>加州大学旧金山分校医学教授莫妮卡·甘地表示,结果表明,两剂疫苗将保护许多人免受导致住院或死亡的严重病例。</blockquote></p><p> “Two doses are still effective against severe disease, whether people get boosters or not,” said Dr. Gandhi, who is recommending boosters for high-risk patients, including those with HIV. “For people who are at high risk of severe disease, it’s so important to get them boosted, but I don’t think it’s mandatory for young healthy people.”</p><p><blockquote>甘地博士说:“无论人们是否接种加强剂,两剂疫苗对严重疾病仍然有效。”他建议为包括艾滋病毒感染者在内的高危患者接种加强剂。“对于患有严重疾病的高风险人群来说,给他们注射疫苗非常重要,但我认为这对于年轻的健康人来说并不是强制性的。”</blockquote></p><p> The company’s early findings come a day after scientists in South Africa reported findings from early lab tests indicating a 41-fold reduction in the Pfizer-BioNTech vaccine’s neutralization of Omicron than the original version of the virus.</p><p><blockquote>该公司的早期发现发布前一天,南非科学家报告了早期实验室测试的结果,表明辉瑞-BioNTech疫苗对奥密克戎病毒的中和作用比原始版本的病毒降低了41倍。</blockquote></p><p> The researchers, however, found greater antibody responses against Omicron in blood taken from subjects who were fully vaccinated and had previously been infected with Covid-19.</p><p><blockquote>然而,研究人员发现,从完全接种疫苗且之前感染过Covid-19的受试者身上采集的血液中,针对奥密克戎病毒的抗体反应更强。</blockquote></p><p> The companies will continue to work on a variant vaccine despite the promising signs that boosting with the original shot offers good protection against Omicron, said BioNTech Chief Executive Uğur Şahin. That is because they would need to see more data on how their vaccine holds up against the new variant, including real-world effectiveness data, expected in the coming weeks.</p><p><blockquote>BioNTech首席执行官Uğur Ş ahin表示,尽管有令人鼓舞的迹象表明,使用原始疫苗加强注射可以很好地预防奥密克戎病,但两家公司仍将继续研究变异疫苗。这是因为他们需要看到更多关于他们的疫苗如何抵抗新变种的数据,包括预计在未来几周内的真实世界有效性数据。</blockquote></p><p> “Only in combination will we understand the relevance of this data and potential protection against Omicron-mediated disease and severe disease,” he said.</p><p><blockquote>他说:“只有结合起来,我们才能了解这些数据的相关性以及对奥密克戎病介导的疾病和严重疾病的潜在保护作用。”</blockquote></p><p> Real-world data on vaccine effectiveness against Omicron won’t be available for at least six weeks, Dr. Şahin said, because the case numbers need to be higher before this can be measured.</p><p><blockquote>Ş ahin博士说,有关奥密克戎疫苗有效性的真实数据至少在六周内无法获得,因为病例数需要更高才能衡量。</blockquote></p><p></p><p> Meanwhile, the companies are moving forward with manufacturing an Omicron-specific vaccine. The first doses, for experimental use, will be ready in January, BioNTech executives said.</p><p><blockquote>与此同时,两家公司正在推进奥密克戎专用疫苗的生产。BioNTech高管表示,用于实验用途的第一剂疫苗将于1月份准备就绪。</blockquote></p><p> Omicron was first identified by scientists in South Africa last month. Since then the World Health Organization has deemed it a variant of concern. And it has since been detected around the world, including in the U.S.</p><p><blockquote>上个月,科学家首次在南非发现了奥密克戎病毒。从那时起,世界卫生组织就认为这是一个值得关注的变种。此后,包括美国在内的世界各地都发现了这种病毒。</blockquote></p><p> Researchers have been trying to understand how contagious the new strain is, as well as how well it might be able to evade Covid-19 vaccines and whether it causes severe disease. Some preliminary reports suggest the variant is more contagious but might cause milder disease, though researchers say it is too early to know.</p><p><blockquote>研究人员一直在试图了解这种新毒株的传染性如何,以及它逃避Covid-19疫苗的能力如何,以及它是否会导致严重疾病。一些初步报告表明,这种变异更具传染性,但可能会导致较轻的疾病,尽管研究人员表示现在知道还为时过早。</blockquote></p><p> Pfizer and BioNTech said they expect to make four billion vaccine doses next year, even if an Omicron-specific vaccine is required by then.</p><p><blockquote>辉瑞和BioNTech表示,他们预计明年将生产40亿剂疫苗,即使届时需要奥密克戎专用疫苗。</blockquote></p><p> Dr. Dolsten said that regardless of how widespread Omicron becomes, continued booster shots will likely be needed going forward to provide protection against Covid-19. A fourth booster dose is likely to be needed in the spring or fall of 2022, he said.</p><p><blockquote>多尔斯滕博士说,无论奥密克戎病变得多么普遍,未来可能需要持续的加强注射来提供针对新冠肺炎的保护。他说,2022年春季或秋季可能需要第四次加强剂量。</blockquote></p><p> “It’s increasingly clear you need to have a long-term perspective, with continued boosting to have strong durable immunity,” said Dr. Dolsten. “If the landscape looks similar to today, we will likely continue to boost with the current vaccine.”</p><p><blockquote>多尔斯滕博士说:“越来越明显的是,你需要有长远的眼光,持续增强才能拥有强大持久的免疫力。”“如果情况看起来与今天相似,我们可能会继续使用当前的疫苗加强疫苗。”</blockquote></p><p> Pfizer’s shares rose 1% while BioNTech’s American depositary shares fell 0.2% in morning trading.</p><p><blockquote>辉瑞股价上涨1%,而BioNTech美国存托股早盘下跌0.2%。</blockquote></p><p></p>\n<div class=\"bt-text\">\n\n\n<p> 来源:<a href=\"https://www.wsj.com/articles/pfizer-biontech-covid-19-vaccine-loses-significant-effectiveness-against-omicron-in-early-study-companies-say-11638964121?mod=hp_lead_pos1\">The Wall Street Journal</a></p>\n<p>为提升您的阅读体验,我们对本页面进行了排版优化</p>\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"BNTX":"BioNTech SE","PFE":"辉瑞"},"source_url":"https://www.wsj.com/articles/pfizer-biontech-covid-19-vaccine-loses-significant-effectiveness-against-omicron-in-early-study-companies-say-11638964121?mod=hp_lead_pos1","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1141815911","content_text":"Pfizer Inc. PFE -0.62% and BioNTech SE BNTX -3.55% said that a third dose of their Covid-19 vaccine neutralized the Omicron variant in lab tests but that the two-dose regimen was significantly less effective at blocking the virus.\n\nA third dose increased antibodies 25-fold compared with two doses against the Omicron variant, the companies said. Still, two doses may prove effective in preventing severe illness from Covid-19, they said, because immune cells are able to recognize 80% of parts of the spike protein that the vaccine targets.\n\nThe results were issued in a press release by the companies, and weren’t peer reviewed and published in a scientific journal.\n\nThe findings from the companies’ early study, and one by scientists in South Africa, suggest that three doses will be needed to produce a similar immune response against Omicron as was provided by just two doses in earlier strains of the virus.\n\n\nIt also bolsters the case for repeated and periodic boosters to maintain people’s immune defenses against an evolving Covid-19, the companies said.\n\n“This is very positive news that should make everyone even more motivated to get vaccinated” and get a booster, said Pfizer Chief Scientific Officer Mikael Dolsten.\n\nThe companies’ current vaccine will provide a strong defense against Omicron, especially if people get a booster shot, Dr. Dolsten said. The three-dose regimen, he added, could provide stopgap protection against Omicron through the winter and until a new vaccine targeted directly at the variant would be ready if needed.\n\nPfizer and BioNTech are working on an Omicron-specific vaccine that they hope to have available by March 2022 if the variant becomes widespread by then. Researchers started working on the new vaccine on Thanksgiving Day, Nov. 25, shortly after Omicron was identified.\n\nThe vaccine trains the immune system to fight the virus by generating immune-system soldiers known as antibodies, which attach to the virus and prevent it from replicating in healthy cells. The vaccine also produces other immune-system fighters called T cells that can kick in after infection to help target and clear the virus, preventing more serious disease.\n\nPfizer and BioNTech said that Omicron still appears susceptible to T cells produced by the vaccine.\n\nDr. Dolsten estimated there is a greater than 50% chance that Omicron becomes the dominant strain spreading in the U.S. by the spring, though it is too soon to know with certainty, he said.\n\nThe preliminary lab data comes from an analysis of blood samples from vaccinated patients measuring antibodies capable of neutralizing the virus causing Covid-19, including the Omicron variant. Blood samples were collected three weeks after patients received their second dose, or one month after receiving their third dose.\n\nThe number of antibodies generated by a third booster shot against Omicron is similar to two doses against an older strain of the virus, the companies said.\n\n“These preliminary data appear to show the Pfizer vaccine does in fact protect against Omicron, and that’s very good news,” said Philip Landrigan, director of Boston College’s Global Public Health and the Global Common Good program.\n\n\nMonica Gandhi, a professor of medicine at the University of California, San Francisco, said the results suggested two doses will protect many people from getting bad cases leading to hospitalization or death.\n\n“Two doses are still effective against severe disease, whether people get boosters or not,” said Dr. Gandhi, who is recommending boosters for high-risk patients, including those with HIV. “For people who are at high risk of severe disease, it’s so important to get them boosted, but I don’t think it’s mandatory for young healthy people.”\n\nThe company’s early findings come a day after scientists in South Africa reported findings from early lab tests indicating a 41-fold reduction in the Pfizer-BioNTech vaccine’s neutralization of Omicron than the original version of the virus.\n\n\n\nThe researchers, however, found greater antibody responses against Omicron in blood taken from subjects who were fully vaccinated and had previously been infected with Covid-19.\n\nThe companies will continue to work on a variant vaccine despite the promising signs that boosting with the original shot offers good protection against Omicron, said BioNTech Chief Executive Uğur Şahin. That is because they would need to see more data on how their vaccine holds up against the new variant, including real-world effectiveness data, expected in the coming weeks.\n\n\n“Only in combination will we understand the relevance of this data and potential protection against Omicron-mediated disease and severe disease,” he said.\n\nReal-world data on vaccine effectiveness against Omicron won’t be available for at least six weeks, Dr. Şahin said, because the case numbers need to be higher before this can be measured.\n\nMeanwhile, the companies are moving forward with manufacturing an Omicron-specific vaccine. The first doses, for experimental use, will be ready in January, BioNTech executives said.\n\nOmicron was first identified by scientists in South Africa last month. Since then the World Health Organization has deemed it a variant of concern. And it has since been detected around the world, including in the U.S.\n\nResearchers have been trying to understand how contagious the new strain is, as well as how well it might be able to evade Covid-19 vaccines and whether it causes severe disease. Some preliminary reports suggest the variant is more contagious but might cause milder disease, though researchers say it is too early to know.\n\nPfizer and BioNTech said they expect to make four billion vaccine doses next year, even if an Omicron-specific vaccine is required by then.\n\nDr. Dolsten said that regardless of how widespread Omicron becomes, continued booster shots will likely be needed going forward to provide protection against Covid-19. A fourth booster dose is likely to be needed in the spring or fall of 2022, he said.\n\n“It’s increasingly clear you need to have a long-term perspective, with continued boosting to have strong durable immunity,” said Dr. Dolsten. “If the landscape looks similar to today, we will likely continue to boost with the current vaccine.”\n\nPfizer’s shares rose 1% while BioNTech’s American depositary shares fell 0.2% in morning trading.","news_type":1,"symbols_score_info":{"PFE":0.9,"BNTX":0.9}},"isVote":1,"tweetType":1,"viewCount":3213,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":606457819,"gmtCreate":1638922877570,"gmtModify":1638922877802,"author":{"id":"3577518888738299","authorId":"3577518888738299","name":"LWZ2218","avatar":"https://static.tigerbbs.com/f53fe88ba02bdf3f307a8e715043f7e2","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3577518888738299","idStr":"3577518888738299"},"themes":[],"htmlText":"Yeah dividend !!!! Buy Buy Buy","listText":"Yeah dividend !!!! Buy Buy Buy","text":"Yeah dividend !!!! Buy Buy Buy","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":4,"commentSize":2,"repostSize":0,"link":"https://laohu8.com/post/606457819","repostId":"2189659313","repostType":4,"isVote":1,"tweetType":1,"viewCount":2429,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":606384315,"gmtCreate":1638835331523,"gmtModify":1638835331731,"author":{"id":"3577518888738299","authorId":"3577518888738299","name":"LWZ2218","avatar":"https://static.tigerbbs.com/f53fe88ba02bdf3f307a8e715043f7e2","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3577518888738299","idStr":"3577518888738299"},"themes":[],"htmlText":"Is time to buy !!!","listText":"Is time to buy !!!","text":"Is time to buy !!!","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":3,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/606384315","repostId":"2189868186","repostType":4,"isVote":1,"tweetType":1,"viewCount":3749,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":608669270,"gmtCreate":1638715185292,"gmtModify":1638715185409,"author":{"id":"3577518888738299","authorId":"3577518888738299","name":"LWZ2218","avatar":"https://static.tigerbbs.com/f53fe88ba02bdf3f307a8e715043f7e2","crmLevel":11,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3577518888738299","idStr":"3577518888738299"},"themes":[],"htmlText":"Is time to buy","listText":"Is time to buy","text":"Is time to buy","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":3,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/608669270","repostId":"1164103185","repostType":4,"repost":{"id":"1164103185","kind":"news","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1638543422,"share":"https://www.laohu8.com/m/news/1164103185?lang=zh_CN&edition=full","pubTime":"2021-12-03 22:57","market":"us","language":"en","title":"Semiconductor stocks slid in morning trading<blockquote>半导体股早盘下跌</blockquote>","url":"https://stock-news.laohu8.com/highlight/detail?id=1164103185","media":"Tiger Newspress","summary":"Semiconductor stocks slid in morning trading.Nvidia,TSMC,ASML and AMD fell about 2% while Marvell Te","content":"<p>Semiconductor stocks slid in morning trading.Nvidia,TSMC,ASML and AMD fell about 2% while Marvell Technology soared 17%.</p><p><blockquote>半导体股早盘下跌。英伟达、台积电、ASML和AMD下跌约2%,而Marvell Technology飙升17%。</blockquote></p><p> <img src=\"https://static.tigerbbs.com/e4d133b94a6a4da67cbdefb76522317d\" tg-width=\"405\" tg-height=\"302\" width=\"100%\" height=\"auto\"></p><p><blockquote></blockquote></p><p></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; 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