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这篇文章不错，转发给大家看看
值得关注的股票：博通、阿里巴巴、雪佛龙、李维斯
亮彩人生
2025-12-15
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Immunome公司宣布治疗肿瘤患者的试验取得积极结果
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class=\"h-time\">2026-07-08 22:06</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>博通 (AVGO) 的股价在苹果公司宣布计划斥资超过300亿美元采购其美国制造的芯片后应声上涨。</p>\n<p>阿里巴巴 (BABA, HK:9988) 的港股和美股存托凭证 (ADR) 双双走高，因投资者将目光转向了不那么拥挤的人工智能交易领域。</p>\n<p>李维斯 (LEVI) 和好市多 (COST) 方面，这家牛仔裤制造商将于今天下午公布第二季度财报；而好市多则将报告六月份的销售数据。</p>\n<p>雪佛龙 (CVX) 和埃克森美孚 (XOM) 的股价随着中东紧张局势升级导致油价飙升而获得提振。</p>\n<p>电动汽车制造商 Rivian Automotive (RIVN) 的股价延续了跌势。此前，该公司因计划增发股票，导致其股价在昨日暴跌了18%。</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"LU1548497426.USD":"安联环球人工智能AT Acc","LU0170899867.USD":"EASTSPRING INVESTMENTS WORLD VALUE EQUITY \"A\" (USD) ACC","LU1868837136.USD":"CT (LUX) I AMERICAN \"8\" (USD) ACC","LU2756315664.SGD":"ALLIANZ INCOME AND GROWTH \"AMI\" (SGDHDG) INC","LU1868836591.USD":"CT (LUX) I AMERICAN \"1U\"(USD) ACC","LU0957791311.USD":"THREADNEEDLE (LUX) GLOBAL FOCUS \"ZU\" (USD) ACC","LU1815333072.USD":"THREADNEEDLE (LUX) GLOBAL FOCUS \"AUP\" (USD) INC","TRFK":"PACER DATA AND DIGITAL REVOLUTION 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Gounder医学博士表示，“RINGSIDE试验中，varegacestat治疗组的无进展生存期获益显著，缓解率高，肿瘤体积缩小，这些结果令人瞩目。这些发现提升了GSI（生长抑素类似物）的作用，并证实varegacestat有望成为纤维瘤治疗的标准疗法。”</p><p style=\"text-align: start;\">Siegall 博士补充道：“RINGSIDE 的结果代表着 Immunome 的一个重要里程碑，因为我们正在推进我们新兴的靶向肿瘤疗法产品线，这些疗法具有显著改善患者生活的巨大潜力。”</p><p style=\"text-align: start;\">Immunome计划在即将举行的大型医学会议上分享RINGSIDE试验的更多数据。</p></body></html>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Immunome公司宣布治疗肿瘤患者的试验取得积极结果</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nImmunome公司宣布治疗肿瘤患者的试验取得积极结果\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/102\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">老虎资讯综合 </p>\n<p class=\"h-time\">2025-12-15 22:40</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<html><head></head><body><p>12月15日，生物制药公司<a href=\"https://laohu8.com/S/IMNM\">Immunome</a>盘初飙升逾20%！公司宣布治疗肿瘤患者的试验取得积极结果。</p><p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/3a27b81b1c6ccb04143119304bb70184\" tg-width=\"560\" tg-height=\"240\"/></p><p style=\"text-align: start;\">致力于开发同类首创和同类最佳靶向癌症疗法的生物技术公司 Immunome, Inc.（纳斯达克股票代码：IMNM）今天宣布，其在研口服每日一次γ-分泌酶抑制剂 (GSI) varegacestat 的全球关键性 3 期 RINGSIDE 试验取得了积极的顶线结果，该试验针对的是进展性纤维瘤患者。</p><p style=\"text-align: start;\">该试验达到了改善无进展生存期的主要终点，与安慰剂相比，显示出具有统计学意义和临床意义的显著改善，疾病进展或死亡风险降低了84%（风险比 (HR) = 0.16，95% 置信区间：0.071，0.375；p<0.0001）。根据 RECIST v1.1 标准，经盲法独立中心审查评估，varegacestat 组的确认客观缓解率 (ORR) 为 56%，而安慰剂组为 9% (p<0.0001)。在探索性分析中，经盲法独立中心审查评估，varegacestat 组的肿瘤体积中位最佳变化为 -83%，而安慰剂组为 +11%。此外，该试验达到了所有关键次要终点，varegacestat 在标志性肿瘤体积缩小和最严重疼痛强度方面均取得了与安慰剂相比具有统计学意义的改善。</p><p style=\"text-align: start;\">Varegacestat总体耐受性良好，安全性可控，与GSI类药物一致。治疗组受试者最常见的不良事件为腹泻（82%）、疲乏（44%）、皮疹（43%）、恶心（35%）和咳嗽（34%）。大多数不良事件为1级或2级。</p><p style=\"text-align: start;\">根据这些数据，Immunome计划于2026年第二季度向美国食品药品监督管理局提交新药申请。</p><p style=\"text-align: start;\">“RINGSIDE 是迄今为止针对纤维瘤患者开展的规模最大、最全面的临床试验，其主要结果代表了该患者群体在随机临床试验中观察到的最高客观缓解率，”Immunome 首席执行官 Clay Siegall 博士表示。“这些发现表明，varegacestat 具有潜力，能够以方便的每日一次口服药物的形式提供一流的疗效，帮助患者重获新生。”</p><p style=\"text-align: start;\">“由于其不可预测的特性以及现有治疗方案的局限性，纤维瘤会对患者的身心造成毁灭性的影响，”纪念斯隆-凯特琳癌症中心肉瘤内科肿瘤学家兼药物研发专家、RINGSIDE试验的主要研究者Mrinal M. Gounder医学博士表示，“RINGSIDE试验中，varegacestat治疗组的无进展生存期获益显著，缓解率高，肿瘤体积缩小，这些结果令人瞩目。这些发现提升了GSI（生长抑素类似物）的作用，并证实varegacestat有望成为纤维瘤治疗的标准疗法。”</p><p style=\"text-align: start;\">Siegall 博士补充道：“RINGSIDE 的结果代表着 Immunome 的一个重要里程碑，因为我们正在推进我们新兴的靶向肿瘤疗法产品线，这些疗法具有显著改善患者生活的巨大潜力。”</p><p style=\"text-align: start;\">Immunome计划在即将举行的大型医学会议上分享RINGSIDE试验的更多数据。</p></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/fb4be1ff4aaa40ac88564f80f173158e","relate_stocks":{"IMNM":"Immunome Inc."},"source_url":"","is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1176318762","content_text":"12月15日，生物制药公司Immunome盘初飙升逾20%！公司宣布治疗肿瘤患者的试验取得积极结果。致力于开发同类首创和同类最佳靶向癌症疗法的生物技术公司 Immunome, Inc.（纳斯达克股票代码：IMNM）今天宣布，其在研口服每日一次γ-分泌酶抑制剂 (GSI) varegacestat 的全球关键性 3 期 RINGSIDE 试验取得了积极的顶线结果，该试验针对的是进展性纤维瘤患者。该试验达到了改善无进展生存期的主要终点，与安慰剂相比，显示出具有统计学意义和临床意义的显著改善，疾病进展或死亡风险降低了84%（风险比 (HR) = 0.16，95% 置信区间：0.071，0.375；p<0.0001）。根据 RECIST v1.1 标准，经盲法独立中心审查评估，varegacestat 组的确认客观缓解率 (ORR) 为 56%，而安慰剂组为 9% (p<0.0001)。在探索性分析中，经盲法独立中心审查评估，varegacestat 组的肿瘤体积中位最佳变化为 -83%，而安慰剂组为 +11%。此外，该试验达到了所有关键次要终点，varegacestat 在标志性肿瘤体积缩小和最严重疼痛强度方面均取得了与安慰剂相比具有统计学意义的改善。Varegacestat总体耐受性良好，安全性可控，与GSI类药物一致。治疗组受试者最常见的不良事件为腹泻（82%）、疲乏（44%）、皮疹（43%）、恶心（35%）和咳嗽（34%）。大多数不良事件为1级或2级。根据这些数据，Immunome计划于2026年第二季度向美国食品药品监督管理局提交新药申请。“RINGSIDE 是迄今为止针对纤维瘤患者开展的规模最大、最全面的临床试验，其主要结果代表了该患者群体在随机临床试验中观察到的最高客观缓解率，”Immunome 首席执行官 Clay Siegall 博士表示。“这些发现表明，varegacestat 具有潜力，能够以方便的每日一次口服药物的形式提供一流的疗效，帮助患者重获新生。”“由于其不可预测的特性以及现有治疗方案的局限性，纤维瘤会对患者的身心造成毁灭性的影响，”纪念斯隆-凯特琳癌症中心肉瘤内科肿瘤学家兼药物研发专家、RINGSIDE试验的主要研究者Mrinal M. Gounder医学博士表示，“RINGSIDE试验中，varegacestat治疗组的无进展生存期获益显著，缓解率高，肿瘤体积缩小，这些结果令人瞩目。这些发现提升了GSI（生长抑素类似物）的作用，并证实varegacestat有望成为纤维瘤治疗的标准疗法。”Siegall 博士补充道：“RINGSIDE 的结果代表着 Immunome 的一个重要里程碑，因为我们正在推进我们新兴的靶向肿瘤疗法产品线，这些疗法具有显著改善患者生活的巨大潜力。”Immunome计划在即将举行的大型医学会议上分享RINGSIDE试验的更多数据。","news_type":1,"symbols_score_info":{"IMNM":2}},"isVote":1,"tweetType":1,"viewCount":739,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0}],"hots":[{"id":511082856846576,"gmtCreate":1765803058341,"gmtModify":1765803299285,"author":{"id":"3575279725388421","authorId":"3575279725388421","name":"亮彩人生","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":9,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3575279725388421","authorIdStr":"3575279725388421"},"themes":[],"title":"","htmlText":"a","listText":"a","text":"a","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/511082856846576","repostId":"1176318762","repostType":2,"repost":{"id":"1176318762","kind":"news","weMediaInfo":{"introduction":"为用户提供金融资讯、行情、数据，旨在帮助投资者理解世界，做投资决策。","home_visible":1,"media_name":"老虎资讯综合","id":"102","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1765809600,"share":"https://www.laohunote.com/m/news/1176318762?lang=zh_CN&edition=full","pubTime":"2025-12-15 22:40","market":"us","language":"zh","title":"Immunome公司宣布治疗肿瘤患者的试验取得积极结果","url":"https://stock-news.laohu8.com/highlight/detail?id=1176318762","media":"老虎资讯综合","summary":"生物制药公司Immunome飙升近40%！公司宣布治疗肿瘤患者的试验取得积极结果。","content":"<html><head></head><body><p>12月15日，生物制药公司<a href=\"https://laohu8.com/S/IMNM\">Immunome</a>盘初飙升逾20%！公司宣布治疗肿瘤患者的试验取得积极结果。</p><p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/3a27b81b1c6ccb04143119304bb70184\" tg-width=\"560\" tg-height=\"240\"/></p><p style=\"text-align: start;\">致力于开发同类首创和同类最佳靶向癌症疗法的生物技术公司 Immunome, Inc.（纳斯达克股票代码：IMNM）今天宣布，其在研口服每日一次γ-分泌酶抑制剂 (GSI) varegacestat 的全球关键性 3 期 RINGSIDE 试验取得了积极的顶线结果，该试验针对的是进展性纤维瘤患者。</p><p style=\"text-align: start;\">该试验达到了改善无进展生存期的主要终点，与安慰剂相比，显示出具有统计学意义和临床意义的显著改善，疾病进展或死亡风险降低了84%（风险比 (HR) = 0.16，95% 置信区间：0.071，0.375；p<0.0001）。根据 RECIST v1.1 标准，经盲法独立中心审查评估，varegacestat 组的确认客观缓解率 (ORR) 为 56%，而安慰剂组为 9% (p<0.0001)。在探索性分析中，经盲法独立中心审查评估，varegacestat 组的肿瘤体积中位最佳变化为 -83%，而安慰剂组为 +11%。此外，该试验达到了所有关键次要终点，varegacestat 在标志性肿瘤体积缩小和最严重疼痛强度方面均取得了与安慰剂相比具有统计学意义的改善。</p><p style=\"text-align: start;\">Varegacestat总体耐受性良好，安全性可控，与GSI类药物一致。治疗组受试者最常见的不良事件为腹泻（82%）、疲乏（44%）、皮疹（43%）、恶心（35%）和咳嗽（34%）。大多数不良事件为1级或2级。</p><p style=\"text-align: start;\">根据这些数据，Immunome计划于2026年第二季度向美国食品药品监督管理局提交新药申请。</p><p style=\"text-align: start;\">“RINGSIDE 是迄今为止针对纤维瘤患者开展的规模最大、最全面的临床试验，其主要结果代表了该患者群体在随机临床试验中观察到的最高客观缓解率，”Immunome 首席执行官 Clay Siegall 博士表示。“这些发现表明，varegacestat 具有潜力，能够以方便的每日一次口服药物的形式提供一流的疗效，帮助患者重获新生。”</p><p style=\"text-align: start;\">“由于其不可预测的特性以及现有治疗方案的局限性，纤维瘤会对患者的身心造成毁灭性的影响，”纪念斯隆-凯特琳癌症中心肉瘤内科肿瘤学家兼药物研发专家、RINGSIDE试验的主要研究者Mrinal M. Gounder医学博士表示，“RINGSIDE试验中，varegacestat治疗组的无进展生存期获益显著，缓解率高，肿瘤体积缩小，这些结果令人瞩目。这些发现提升了GSI（生长抑素类似物）的作用，并证实varegacestat有望成为纤维瘤治疗的标准疗法。”</p><p style=\"text-align: start;\">Siegall 博士补充道：“RINGSIDE 的结果代表着 Immunome 的一个重要里程碑，因为我们正在推进我们新兴的靶向肿瘤疗法产品线，这些疗法具有显著改善患者生活的巨大潜力。”</p><p style=\"text-align: start;\">Immunome计划在即将举行的大型医学会议上分享RINGSIDE试验的更多数据。</p></body></html>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Immunome公司宣布治疗肿瘤患者的试验取得积极结果</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nImmunome公司宣布治疗肿瘤患者的试验取得积极结果\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/102\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">老虎资讯综合 </p>\n<p class=\"h-time\">2025-12-15 22:40</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<html><head></head><body><p>12月15日，生物制药公司<a href=\"https://laohu8.com/S/IMNM\">Immunome</a>盘初飙升逾20%！公司宣布治疗肿瘤患者的试验取得积极结果。</p><p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/3a27b81b1c6ccb04143119304bb70184\" tg-width=\"560\" tg-height=\"240\"/></p><p style=\"text-align: start;\">致力于开发同类首创和同类最佳靶向癌症疗法的生物技术公司 Immunome, Inc.（纳斯达克股票代码：IMNM）今天宣布，其在研口服每日一次γ-分泌酶抑制剂 (GSI) varegacestat 的全球关键性 3 期 RINGSIDE 试验取得了积极的顶线结果，该试验针对的是进展性纤维瘤患者。</p><p style=\"text-align: start;\">该试验达到了改善无进展生存期的主要终点，与安慰剂相比，显示出具有统计学意义和临床意义的显著改善，疾病进展或死亡风险降低了84%（风险比 (HR) = 0.16，95% 置信区间：0.071，0.375；p<0.0001）。根据 RECIST v1.1 标准，经盲法独立中心审查评估，varegacestat 组的确认客观缓解率 (ORR) 为 56%，而安慰剂组为 9% (p<0.0001)。在探索性分析中，经盲法独立中心审查评估，varegacestat 组的肿瘤体积中位最佳变化为 -83%，而安慰剂组为 +11%。此外，该试验达到了所有关键次要终点，varegacestat 在标志性肿瘤体积缩小和最严重疼痛强度方面均取得了与安慰剂相比具有统计学意义的改善。</p><p style=\"text-align: start;\">Varegacestat总体耐受性良好，安全性可控，与GSI类药物一致。治疗组受试者最常见的不良事件为腹泻（82%）、疲乏（44%）、皮疹（43%）、恶心（35%）和咳嗽（34%）。大多数不良事件为1级或2级。</p><p style=\"text-align: start;\">根据这些数据，Immunome计划于2026年第二季度向美国食品药品监督管理局提交新药申请。</p><p style=\"text-align: start;\">“RINGSIDE 是迄今为止针对纤维瘤患者开展的规模最大、最全面的临床试验，其主要结果代表了该患者群体在随机临床试验中观察到的最高客观缓解率，”Immunome 首席执行官 Clay Siegall 博士表示。“这些发现表明，varegacestat 具有潜力，能够以方便的每日一次口服药物的形式提供一流的疗效，帮助患者重获新生。”</p><p style=\"text-align: start;\">“由于其不可预测的特性以及现有治疗方案的局限性，纤维瘤会对患者的身心造成毁灭性的影响，”纪念斯隆-凯特琳癌症中心肉瘤内科肿瘤学家兼药物研发专家、RINGSIDE试验的主要研究者Mrinal M. Gounder医学博士表示，“RINGSIDE试验中，varegacestat治疗组的无进展生存期获益显著，缓解率高，肿瘤体积缩小，这些结果令人瞩目。这些发现提升了GSI（生长抑素类似物）的作用，并证实varegacestat有望成为纤维瘤治疗的标准疗法。”</p><p style=\"text-align: start;\">Siegall 博士补充道：“RINGSIDE 的结果代表着 Immunome 的一个重要里程碑，因为我们正在推进我们新兴的靶向肿瘤疗法产品线，这些疗法具有显著改善患者生活的巨大潜力。”</p><p style=\"text-align: start;\">Immunome计划在即将举行的大型医学会议上分享RINGSIDE试验的更多数据。</p></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/fb4be1ff4aaa40ac88564f80f173158e","relate_stocks":{"IMNM":"Immunome Inc."},"source_url":"","is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1176318762","content_text":"12月15日，生物制药公司Immunome盘初飙升逾20%！公司宣布治疗肿瘤患者的试验取得积极结果。致力于开发同类首创和同类最佳靶向癌症疗法的生物技术公司 Immunome, Inc.（纳斯达克股票代码：IMNM）今天宣布，其在研口服每日一次γ-分泌酶抑制剂 (GSI) varegacestat 的全球关键性 3 期 RINGSIDE 试验取得了积极的顶线结果，该试验针对的是进展性纤维瘤患者。该试验达到了改善无进展生存期的主要终点，与安慰剂相比，显示出具有统计学意义和临床意义的显著改善，疾病进展或死亡风险降低了84%（风险比 (HR) = 0.16，95% 置信区间：0.071，0.375；p<0.0001）。根据 RECIST v1.1 标准，经盲法独立中心审查评估，varegacestat 组的确认客观缓解率 (ORR) 为 56%，而安慰剂组为 9% (p<0.0001)。在探索性分析中，经盲法独立中心审查评估，varegacestat 组的肿瘤体积中位最佳变化为 -83%，而安慰剂组为 +11%。此外，该试验达到了所有关键次要终点，varegacestat 在标志性肿瘤体积缩小和最严重疼痛强度方面均取得了与安慰剂相比具有统计学意义的改善。Varegacestat总体耐受性良好，安全性可控，与GSI类药物一致。治疗组受试者最常见的不良事件为腹泻（82%）、疲乏（44%）、皮疹（43%）、恶心（35%）和咳嗽（34%）。大多数不良事件为1级或2级。根据这些数据，Immunome计划于2026年第二季度向美国食品药品监督管理局提交新药申请。“RINGSIDE 是迄今为止针对纤维瘤患者开展的规模最大、最全面的临床试验，其主要结果代表了该患者群体在随机临床试验中观察到的最高客观缓解率，”Immunome 首席执行官 Clay Siegall 博士表示。“这些发现表明，varegacestat 具有潜力，能够以方便的每日一次口服药物的形式提供一流的疗效，帮助患者重获新生。”“由于其不可预测的特性以及现有治疗方案的局限性，纤维瘤会对患者的身心造成毁灭性的影响，”纪念斯隆-凯特琳癌症中心肉瘤内科肿瘤学家兼药物研发专家、RINGSIDE试验的主要研究者Mrinal M. Gounder医学博士表示，“RINGSIDE试验中，varegacestat治疗组的无进展生存期获益显著，缓解率高，肿瘤体积缩小，这些结果令人瞩目。这些发现提升了GSI（生长抑素类似物）的作用，并证实varegacestat有望成为纤维瘤治疗的标准疗法。”Siegall 博士补充道：“RINGSIDE 的结果代表着 Immunome 的一个重要里程碑，因为我们正在推进我们新兴的靶向肿瘤疗法产品线，这些疗法具有显著改善患者生活的巨大潜力。”Immunome计划在即将举行的大型医学会议上分享RINGSIDE试验的更多数据。","news_type":1,"symbols_score_info":{"IMNM":2}},"isVote":1,"tweetType":1,"viewCount":739,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":583725664408072,"gmtCreate":1783542664440,"gmtModify":1783558803834,"author":{"id":"3575279725388421","authorId":"3575279725388421","name":"亮彩人生","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":9,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3575279725388421","authorIdStr":"3575279725388421"},"themes":[],"title":"","htmlText":"这篇文章不错，转发给大家看看","listText":"这篇文章不错，转发给大家看看","text":"这篇文章不错，转发给大家看看","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/583725664408072","repostId":"1138098711","repostType":2,"repost":{"id":"1138098711","kind":"news","weMediaInfo":{"introduction":"关注海外资本市场一手动态","home_visible":1,"media_name":"投资观察","id":"1076224072","head_image":"https://community-static.tradeup.com/news/8296859682db4b478146245e72de1922"},"pubTimestamp":1783519597,"share":"https://www.laohunote.com/m/news/1138098711?lang=zh_CN&edition=full","pubTime":"2026-07-08 22:06","market":"hk","language":"zh","title":"值得关注的股票：博通、阿里巴巴、雪佛龙、李维斯","url":"https://stock-news.laohu8.com/highlight/detail?id=1138098711","media":"投资观察","summary":"博通 的股价在苹果公司宣布计划斥资超过300亿美元采购其美国制造的芯片后应声上涨。李维斯 和好市多 方面，这家牛仔裤制造商将于今天下午公布第二季度财报；而好市多则将报告六月份的销售数据。雪佛龙 和埃克森美孚 的股价随着中东紧张局势升级导致油价飙升而获得提振。电动汽车制造商 Rivian Automotive 的股价延续了跌势。此前，该公司因计划增发股票，导致其股价在昨日暴跌了18%。","content":"<p>博通 (AVGO) 的股价在苹果公司宣布计划斥资超过300亿美元采购其美国制造的芯片后应声上涨。</p>\n<p>阿里巴巴 (BABA, HK:9988) 的港股和美股存托凭证 (ADR) 双双走高，因投资者将目光转向了不那么拥挤的人工智能交易领域。</p>\n<p>李维斯 (LEVI) 和好市多 (COST) 方面，这家牛仔裤制造商将于今天下午公布第二季度财报；而好市多则将报告六月份的销售数据。</p>\n<p>雪佛龙 (CVX) 和埃克森美孚 (XOM) 的股价随着中东紧张局势升级导致油价飙升而获得提振。</p>\n<p>电动汽车制造商 Rivian Automotive (RIVN) 的股价延续了跌势。此前，该公司因计划增发股票，导致其股价在昨日暴跌了18%。</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>值得关注的股票：博通、阿里巴巴、雪佛龙、李维斯</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; 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height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n值得关注的股票：博通、阿里巴巴、雪佛龙、李维斯\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1076224072\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://community-static.tradeup.com/news/8296859682db4b478146245e72de1922);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">投资观察 </p>\n<p class=\"h-time\">2026-07-08 22:06</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>博通 (AVGO) 的股价在苹果公司宣布计划斥资超过300亿美元采购其美国制造的芯片后应声上涨。</p>\n<p>阿里巴巴 (BABA, HK:9988) 的港股和美股存托凭证 (ADR) 双双走高，因投资者将目光转向了不那么拥挤的人工智能交易领域。</p>\n<p>李维斯 (LEVI) 和好市多 (COST) 方面，这家牛仔裤制造商将于今天下午公布第二季度财报；而好市多则将报告六月份的销售数据。</p>\n<p>雪佛龙 (CVX) 和埃克森美孚 (XOM) 的股价随着中东紧张局势升级导致油价飙升而获得提振。</p>\n<p>电动汽车制造商 Rivian Automotive (RIVN) 的股价延续了跌势。此前，该公司因计划增发股票，导致其股价在昨日暴跌了18%。</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"LU1548497426.USD":"安联环球人工智能AT Acc","LU0170899867.USD":"EASTSPRING INVESTMENTS WORLD VALUE EQUITY \"A\" (USD) ACC","LU1868837136.USD":"CT (LUX) I AMERICAN \"8\" (USD) ACC","LU2756315664.SGD":"ALLIANZ INCOME AND GROWTH \"AMI\" (SGDHDG) INC","LU1868836591.USD":"CT (LUX) I AMERICAN \"1U\"(USD) ACC","LU0957791311.USD":"THREADNEEDLE (LUX) GLOBAL FOCUS \"ZU\" (USD) ACC","LU1815333072.USD":"THREADNEEDLE (LUX) GLOBAL FOCUS \"AUP\" (USD) INC","TRFK":"PACER DATA AND DIGITAL REVOLUTION ETF","LU1868836757.USD":"CT (LUX) I AMERICAN FUND \"2\" (USD) ACC","LU1316542783.SGD":"Janus Henderson Horizon Global Technology Leaders A2 SGD","LU1935043023.USD":"MANULIFE GF GLOBAL MULTI-ASSET DIVERSIFIED INCOME \"AA\" (USD) INC A","AIFD":"TCW Artificial Intelligence ETF","LU1242518857.USD":"FULLERTON LUX FUNDS - ASIA ABSOLUTE ALPHA \"I\" (USD) ACC","BK4202":"服装、服饰与奢侈品","LU0471298777.SGD":"Blackrock Nutrition A2 SGD-H","BABO":"BABA期权收益策略ETF-YieldMax","IE00BBT3K403.USD":"LEGG MASON CLEARBRIDGE TACTICAL DIVIDEND INCOME \"A(USD) ACC","SG9999003800.SGD":"Nikko AM Global Dividend Equity Acc SGD-H","BK4565":"NFT概念","LU2746668461.USD":"MANULIFE DYNAMIC LEADERS \"AA\" (USD) ACC","BABU":"Direxion Daily BABA Bull 2X ETF","BK4201":"综合性石油与天然气企业","IGE":"北美自然资源ETF-iShares","LU0642271901.SGD":"Janus Henderson Horizon Global Technology Leaders A2 SGD-H","LU2102340556.USD":"AZ ALLOCATION - RISK PARITY FACTOR \"A\" (USD) ACC","BABW":"Roundhill BABA WeeklyPay ETF","IE00B5949003.HKD":"JANUS HENDERSON GLOBAL TECHNOLOGY AND INNOVATION \"A\" (HKD) ACC","LU1582986433.USD":"M&G (LUX) INCOME ALLOCATION \"A-H\" (USDHDG) INC","BK4155":"大卖场与超市","LU0320765489.SGD":"FTIF - Franklin Mutual US Value A Acc SGD","LU1489326972.SGD":"First Eagle Amundi International AHS-MD SGD-H","LU2089985449.USD":"MANULIFE GF GLOBAL SEMICONDUCTOR OPPORTUNITIES \"AA\" (USD) ACC","BABX":"2倍做多BABA ETF-GraniteShares","LU1035775433.USD":"AB SICAV I - AMERICAN GROWTH PORTFOLIO \"AD\" (USD) INC","LU1803068979.SGD":"FTIF - Franklin Technology A (acc) SGD-H1","LU1430594728.SGD":"Eastspring Investments - Global Low Volatility Equity AS SGD","LU2931357623.SGD":"MANULIFE GF GLOBAL SEMICONDUCTOR OPPORTUNITIES \"AA\" (SGDHDG) ACC","LU2756315318.SGD":"ALLIANZ INCOME AND GROWTH \"AMG\" (SGDHDG) INC A","LU2746668974.SGD":"MANULIFE DYNAMIC LEADERS \"AA\" (SGDHDG) ACC","LU0949170772.SGD":"Blackrock Global Equity Income A6 SGD-H","TEK":"iShares Technology Opportunities Active ETF","SG9999002232.USD":"Allianz Global High Payout USD","IE0008368304.USD":"STEWART INVESTORS WORLDWIDE LEADERS SUSTAINABILITY FUND \"I\" (USD) ACC","LU1003077747.HKD":"BGF GLOBAL EQUITY INCOME \"A6\" (HKDHDG) INC","BK4566":"资本集团","SG9999002224.SGD":"Allianz Global High Payout SGD","SG9999015341.SGD":"United Income Focus Trust Acc SGD-H","USXF":"iShares ESG Advanced MSCI USA ETF","BAI":"iShares A.I. 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