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2021-06-08

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Millions of J&J Covid-19 Vaccines Are at Risk of Expiring in June<blockquote>数百万 J&J Covid-19 疫苗面临六月过期的风险</blockquote>

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Hospitals, state health departments and the federal government are racing to decide how to use up millions ofJohnson &amp; Johnson’sJNJ-0.68%Covid-19vaccine doses that are set to expire this month.<blockquote>各州和医院试图改变这种疫苗的路线，而出口它们的努力面临障碍。医院、州卫生部门和联邦政府正在争先恐后地决定如何用完将于本月到期的数百万剂强生公司的 sJNJ-0.68%COVID-19 疫苗。</blockquote> The prospect of so many doses going to waste in the U.S. whendeveloping nations are desperatefor shots would add pressure on the Biden administration to share stockpiled vaccines. But there are few practical solutions to administering them quickly in the U.S. or distributing them in time to foreign countries, according to those involved in the vaccination drive.<blockquote>当发展中国家迫切需要疫苗时，美国会浪费如此多的疫苗，这将增加拜登政府分享库存疫苗的压力。但据参与疫苗接种活动的人士称，在美国快速接种疫苗或及时分发到外国几乎没有切实可行的解决方案。</blockquote> The stockpile is, in part, an unintended consequence of the U.S.’s decision in April totemporarily suspend administrationof J&amp;J doses to assess a rare blood-clot risk. The pause forced states and providers tocancel large blocksof appointments that were never rescheduled, leaving a surplus of supply, andin some areas increasing hesitancyover the J&amp;J vaccine’s safety, according to industry officials.<blockquote>库存的部分原因是美国在 4 月份决定暂时中止强生疫苗的使用，以评估罕见的血栓风险，这是一个意想不到的后果。据行业官员称，暂停迫使各州和医疗服务提供商取消了大批从未重新安排的预约，导致供应过剩，在一些地区，人们对强生疫苗的安全性越来越犹豫。</blockquote> Some hospitals and states say that vaccines fromPfizerInc.and partnerBioNTech SE,as well asModernaInc.,are due to expire later this summer, but the stockpiles so far are largely of J&amp;J doses. Pfizer’s vaccine expires six months after manufacture. Moderna’s vaccine can remain frozen for up to six months, during which it can be refrigerated for one month.<blockquote>一些医院和州表示，辉瑞公司和合作伙伴BioNTech SE以及ModernaInc.的疫苗将于今年夏天晚些时候到期，但迄今为止的库存主要是强生疫苗。辉瑞公司的疫苗在生产六个月后过期。Moderna 的疫苗可以冷冻保存长达六个月，在此期间可以冷藏一个月。</blockquote> Philadelphia has 42,000 J&amp;J doses set to expire, most of which came from a Federal Emergency Management Agency clinic at the city’s convention center a few days before the pause, a city spokesman said. Pennsylvania, West Virginia, Oklahoma and Arkansas are among states that report having thousands of J&amp;J doses set to expire this month and have been unable to redistribute them.<blockquote>费城发言人说，费城有 42,000 剂强生疫苗即将过期，其中大部分来自暂停前几天位于该市会议中心的联邦紧急事务管理局诊所。宾夕法尼亚州、西弗吉尼亚州、俄克拉荷马州和阿肯色州等州报告称，数千剂强生疫苗将于本月到期，并且无法重新分配。</blockquote> “There’s no way at the end of June that we’re not going to have a couple thousand expiring,” said Danielle Hilborn, who helps oversee Covid-19 vaccines for McLaren Health Care Corp. The hospital system based outside Flint, Mich., has more than 3,500 J&amp;J doses set to expire this month, despite having moved doses among its hospitals and shipped 1,100 to a county health department.<blockquote>“麦克拉伦医疗保健公司（McLaren Health Care Corp.）帮助监督 Covid-19 疫苗的丹妮尔-希尔伯恩（Danielle Hilborn）说：”到 6 月底，我们不可能没有几千支疫苗过期。总部位于密歇根州弗林特郊外的医院系统有超过3500剂强生疫苗将于本月到期，尽管它已经在医院之间转移了剂量，并将1100剂运送到了县卫生部门。</blockquote> Hospitals and public-health departments offering the shots have begun special promotions to use J&amp;J’s shots before they go bad. Some health systems have redistributed them inside and outside their networks, and some states have rerouted them to physician offices, pharmacies or other states.<blockquote>提供这种注射的医院和公共卫生部门已经开始特别促销活动，以便在强生注射变质之前使用它们。一些卫生系统已经将它们重新分配到网络内外，一些州已经将它们重新分配到医生办公室、药房或其他州。</blockquote> The efforts have had limited success because of thenation’s slowdown in overall vaccinationsand because many states and vaccination sites also have expiring J&amp;J supply and don’t see demand for more doses. Just over half of the 21.4 million J&amp;J shots distributed to providers have been administered, according to data from the Centers for Disease Control and Prevention, versus 83% for shots from Moderna Inc. as well as Pfizer Inc. and its partner, BioNTech.<blockquote>由于全国整体疫苗接种速度放缓，而且许多州和疫苗接种点的强生疫苗供应也即将到期，因此这些努力收效甚微。根据美国疾病控制和预防中心的数据，分发给医疗服务提供者的 2140 万剂强生疫苗中，只有一半多一点已经接种，而 Moderna Inc. 以及辉瑞公司及其合作伙伴 BioNTech 的疫苗接种率为 83%。</blockquote> J&amp;J stores doses frozen until shipment by the government, at which point they are refrigerated. Doses can be refrigerated for three months, and the drugmaker is studying whether the shelf life can be extended, a company spokesman said.<blockquote>强生储存冷冻剂量，直到政府发货，然后冷藏。公司发言人表示，剂量可以冷藏三个月，制药商正在研究是否可以延长保质期。</blockquote> Many drugs and vaccines can remain effective for years, but all eventually start to lose potency. Typically, expiring prescription drugs and vaccines for other diseases are sent to other healthcare facilities, overseas or back to manufacturers, hospital officials said.<blockquote>许多药物和疫苗可以保持多年有效，但最终都开始失去效力。医院官员表示，通常情况下，过期的处方药和其他疾病的疫苗会被送往其他医疗机构、海外或返回制造商。</blockquote> Covid-19 vaccines come with expiration information, which is determined by manufacturers based on testing data that is later cleared by regulators. Vaccines may still work after the expiration dates, according to manufacturing experts, but data was limited when the vaccines were authorized.<blockquote>新冠肺炎疫苗带有过期信息，该信息由制造商根据测试数据确定，随后由监管机构批准。据制造专家称，疫苗在有效期过后可能仍然有效，但疫苗获得授权时的数据有限。</blockquote> The issue of expiring doses is the latest setback for J&amp;J’s Covid-19 vaccine effort. An accident at a contract manufacturer’s plant led to thecontamination of materialthat could have yielded up to 15 million doses and led to a halt in production of the J&amp;J vaccine there.<blockquote>剂量过期问题是强生公司 Covid-19 疫苗工作的最新挫折。一家合同制造商的工厂发生事故，导致原本可生产多达 1500 万剂疫苗的材料受到污染，并导致强生疫苗在那里的生产停止。</blockquote> Dr. Bechara Choucair, the White House vaccine coordinator, has briefed governors and local health officials on best practices to maximize supply, according to a White House official, who also cited ongoing U.S. Food and Drug Administration reviews of whether J&amp;J doses may have longer shelf lives. A second administration official said recalling doses that have already been shipped out to vaccination sites to potentially redistribute them would be logistically and legally challenging.<blockquote>据一名白宫官员称，白宫疫苗协调员Bechara Choucair博士已经向州长和地方卫生官员介绍了最大限度供应的最佳做法，他还引用了正在进行的美国疫苗接种。美国食品药品监督管理局审查强生剂量是否可能有更长的保质期。第二位政府官员表示，召回已经运往疫苗接种点的疫苗并可能重新分配将在后勤和法律上具有挑战性。</blockquote> One of the administration officials said most Covid-19 vaccines in the U.S. aren’t close to expiring.<blockquote>一位政府官员说，美国的大多数 Covid-19 疫苗还没有接近过期。</blockquote> State health departments and hospital officials say the guidance from states and the CDC is to destroy or discard expired doses. The CDC didn’t respond to requests for comment.<blockquote>州卫生部门和医院官员表示，各州和疾病预防控制中心的指导是销毁或丢弃过期剂量。疾病预防控制中心没有回应置评请求。</blockquote> In early April, U.S. regulators paused the use of J&amp;J’s vaccine after reports ofrare but severe blood clots. In response, vaccination sites across the country canceled thousands of appointments and instead offered people Pfizer or Moderna doses. Regulators lifted the pause 10 days later, with J&amp;J and regulators adding language to the vaccine’s label warning of a risk of blood clots.<blockquote>4 月初，美国监管机构在报告出现轻微但严重的血栓后暂停了强生疫苗的使用。作为回应，全国各地的疫苗接种点取消了数千个预约，转而向人们提供辉瑞或Moderna剂量。10 天后，监管机构取消了暂停令，强生公司和监管机构在疫苗标签上添加了警告血栓风险的措辞。</blockquote> By then, patient demand for Covid-19 vaccines shifted from mass-vaccination to smaller community settings amid lingering concerns about the rare clots, according to industry and state officials.<blockquote>据行业和州政府官员称，到那时，由于对罕见血栓的持续担忧，患者对 Covid-19 疫苗的需求已从大规模疫苗接种转移到较小的社区环境。</blockquote> The regulatory pause and overall slowdown in vaccinations has left UofL Health in Louisville, Ky., with more than 6,000 J&amp;J doses that expire this month, after having administered about 2,600 since early April, said Dr. Jason Smith, chief medical officer. “My bet is that we will wind up wasting some of that, unfortunately,” he said.<blockquote>监管暂停和疫苗接种的整体放缓使得肯塔基州路易斯维尔的UofL Health离开了。首席医疗官杰森·史密斯博士说，自4月初以来，J&amp;J已经注射了约2600剂，本月将有6000多剂强生疫苗到期。“他说：”我敢打赌，不幸的是，我们最终会浪费其中的一部分。</blockquote> To use them, the health system is trying to reach physician offices outside its network, Dr. Smith said.<blockquote>史密斯博士说，为了使用它们，卫生系统正试图联系其网络之外的医生办公室。</blockquote> Pennsylvania’s Department of Health said it worked with the CDC and Chester County to try to transfer the county’s 50,000 expiring J&amp;J doses to Oregon. The deal fell through when Oregon experienced a decline in demand and no longer wanted them, a Pennsylvania health department spokesman said.<blockquote>宾夕法尼亚州卫生部表示，它与疾病预防控制中心和切斯特县合作，试图将该县即将到期的 5 万剂强生疫苗转移到俄勒冈州。宾夕法尼亚州卫生部发言人说，当俄勒冈州的需求下降，不再需要他们时，这笔交易失败了。</blockquote> The full extent of expiring Covid-19 vaccines is unknown because providers aren’t required to report it to the federal government, said Jessica Daley, a pharmacist and executive atPremierInc.,a large group-purchasing organization for hospitals.<blockquote>大型医院团购机构 PremierInc. 的药剂师兼高管杰西卡-戴利（Jessica Daley）说，到期的 Covid-19 疫苗的全部过期程度尚不清楚，因为供应商无需向联邦政府报告。</blockquote> Premier is asking members whether they have expiring vaccines, and at least a dozen have said they have expiring J&amp;J doses, Ms. Daley said. “It’s not as simple as just moving the vaccine somewhere else,” she said.<blockquote>戴利女士说，总理正在询问成员们是否有即将过期的疫苗，至少有十几个人说他们有即将过期的强生疫苗。“她说：”这不仅仅是把疫苗转移到其他地方那么简单。</blockquote> Some states say they have asked the U.S. government whether doses can be shipped to developing nations. Doing so faces significant logistical and legal hurdles, according to the United Nations Children’s Fund, because those countries are wary of using vaccines after expiration dates and may not be able to administer them quickly.<blockquote>一些州表示，他们已经询问美国政府是否可以向发展中国家运送疫苗。联合国儿童基金会表示，这样做面临着巨大的后勤和法律障碍，因为这些国家对使用过期疫苗持谨慎态度，可能无法快速接种。</blockquote>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Millions of J&J Covid-19 Vaccines Are at Risk of Expiring in June<blockquote>数百万 J&amp;J Covid-19 疫苗面临六月过期的风险</blockquote></title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 12.5px; color: #7E829C; margin: 0;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nMillions of J&J Covid-19 Vaccines Are at Risk of Expiring in June<blockquote>数百万 J&amp;J Covid-19 疫苗面临六月过期的风险</blockquote>\n</h2>\n<h4 class=\"meta\">\n\nThe Wall Street Journal2021-06-08 21:04\n\n</h4>\n</header>\n<article>\n States, hospitals try to reroute such vaccines, while efforts to export them face hurdles. Hospitals, state health departments and the federal government are racing to decide how to use up millions ofJohnson &amp; Johnson’sJNJ-0.68%Covid-19vaccine doses that are set to expire this month.<blockquote>各州和医院试图改变这种疫苗的路线，而出口它们的努力面临障碍。医院、州卫生部门和联邦政府正在争先恐后地决定如何用完将于本月到期的数百万剂强生公司的 sJNJ-0.68%COVID-19 疫苗。</blockquote> The prospect of so many doses going to waste in the U.S. whendeveloping nations are desperatefor shots would add pressure on the Biden administration to share stockpiled vaccines. But there are few practical solutions to administering them quickly in the U.S. or distributing them in time to foreign countries, according to those involved in the vaccination drive.<blockquote>当发展中国家迫切需要疫苗时，美国会浪费如此多的疫苗，这将增加拜登政府分享库存疫苗的压力。但据参与疫苗接种活动的人士称，在美国快速接种疫苗或及时分发到外国几乎没有切实可行的解决方案。</blockquote> The stockpile is, in part, an unintended consequence of the U.S.’s decision in April totemporarily suspend administrationof J&amp;J doses to assess a rare blood-clot risk. The pause forced states and providers tocancel large blocksof appointments that were never rescheduled, leaving a surplus of supply, andin some areas increasing hesitancyover the J&amp;J vaccine’s safety, according to industry officials.<blockquote>库存的部分原因是美国在 4 月份决定暂时中止强生疫苗的使用，以评估罕见的血栓风险，这是一个意想不到的后果。据行业官员称，暂停迫使各州和医疗服务提供商取消了大批从未重新安排的预约，导致供应过剩，在一些地区，人们对强生疫苗的安全性越来越犹豫。</blockquote> Some hospitals and states say that vaccines fromPfizerInc.and partnerBioNTech SE,as well asModernaInc.,are due to expire later this summer, but the stockpiles so far are largely of J&amp;J doses. Pfizer’s vaccine expires six months after manufacture. Moderna’s vaccine can remain frozen for up to six months, during which it can be refrigerated for one month.<blockquote>一些医院和州表示，辉瑞公司和合作伙伴BioNTech SE以及ModernaInc.的疫苗将于今年夏天晚些时候到期，但迄今为止的库存主要是强生疫苗。辉瑞公司的疫苗在生产六个月后过期。Moderna 的疫苗可以冷冻保存长达六个月，在此期间可以冷藏一个月。</blockquote> Philadelphia has 42,000 J&amp;J doses set to expire, most of which came from a Federal Emergency Management Agency clinic at the city’s convention center a few days before the pause, a city spokesman said. Pennsylvania, West Virginia, Oklahoma and Arkansas are among states that report having thousands of J&amp;J doses set to expire this month and have been unable to redistribute them.<blockquote>费城发言人说，费城有 42,000 剂强生疫苗即将过期，其中大部分来自暂停前几天位于该市会议中心的联邦紧急事务管理局诊所。宾夕法尼亚州、西弗吉尼亚州、俄克拉荷马州和阿肯色州等州报告称，数千剂强生疫苗将于本月到期，并且无法重新分配。</blockquote> “There’s no way at the end of June that we’re not going to have a couple thousand expiring,” said Danielle Hilborn, who helps oversee Covid-19 vaccines for McLaren Health Care Corp. The hospital system based outside Flint, Mich., has more than 3,500 J&amp;J doses set to expire this month, despite having moved doses among its hospitals and shipped 1,100 to a county health department.<blockquote>“麦克拉伦医疗保健公司（McLaren Health Care Corp.）帮助监督 Covid-19 疫苗的丹妮尔-希尔伯恩（Danielle Hilborn）说：”到 6 月底，我们不可能没有几千支疫苗过期。总部位于密歇根州弗林特郊外的医院系统有超过3500剂强生疫苗将于本月到期，尽管它已经在医院之间转移了剂量，并将1100剂运送到了县卫生部门。</blockquote> Hospitals and public-health departments offering the shots have begun special promotions to use J&amp;J’s shots before they go bad. Some health systems have redistributed them inside and outside their networks, and some states have rerouted them to physician offices, pharmacies or other states.<blockquote>提供这种注射的医院和公共卫生部门已经开始特别促销活动，以便在强生注射变质之前使用它们。一些卫生系统已经将它们重新分配到网络内外，一些州已经将它们重新分配到医生办公室、药房或其他州。</blockquote> The efforts have had limited success because of thenation’s slowdown in overall vaccinationsand because many states and vaccination sites also have expiring J&amp;J supply and don’t see demand for more doses. Just over half of the 21.4 million J&amp;J shots distributed to providers have been administered, according to data from the Centers for Disease Control and Prevention, versus 83% for shots from Moderna Inc. as well as Pfizer Inc. and its partner, BioNTech.<blockquote>由于全国整体疫苗接种速度放缓，而且许多州和疫苗接种点的强生疫苗供应也即将到期，因此这些努力收效甚微。根据美国疾病控制和预防中心的数据，分发给医疗服务提供者的 2140 万剂强生疫苗中，只有一半多一点已经接种，而 Moderna Inc. 以及辉瑞公司及其合作伙伴 BioNTech 的疫苗接种率为 83%。</blockquote> J&amp;J stores doses frozen until shipment by the government, at which point they are refrigerated. Doses can be refrigerated for three months, and the drugmaker is studying whether the shelf life can be extended, a company spokesman said.<blockquote>强生储存冷冻剂量，直到政府发货，然后冷藏。公司发言人表示，剂量可以冷藏三个月，制药商正在研究是否可以延长保质期。</blockquote> Many drugs and vaccines can remain effective for years, but all eventually start to lose potency. Typically, expiring prescription drugs and vaccines for other diseases are sent to other healthcare facilities, overseas or back to manufacturers, hospital officials said.<blockquote>许多药物和疫苗可以保持多年有效，但最终都开始失去效力。医院官员表示，通常情况下，过期的处方药和其他疾病的疫苗会被送往其他医疗机构、海外或返回制造商。</blockquote> Covid-19 vaccines come with expiration information, which is determined by manufacturers based on testing data that is later cleared by regulators. Vaccines may still work after the expiration dates, according to manufacturing experts, but data was limited when the vaccines were authorized.<blockquote>新冠肺炎疫苗带有过期信息，该信息由制造商根据测试数据确定，随后由监管机构批准。据制造专家称，疫苗在有效期过后可能仍然有效，但疫苗获得授权时的数据有限。</blockquote> The issue of expiring doses is the latest setback for J&amp;J’s Covid-19 vaccine effort. An accident at a contract manufacturer’s plant led to thecontamination of materialthat could have yielded up to 15 million doses and led to a halt in production of the J&amp;J vaccine there.<blockquote>剂量过期问题是强生公司 Covid-19 疫苗工作的最新挫折。一家合同制造商的工厂发生事故，导致原本可生产多达 1500 万剂疫苗的材料受到污染，并导致强生疫苗在那里的生产停止。</blockquote> Dr. Bechara Choucair, the White House vaccine coordinator, has briefed governors and local health officials on best practices to maximize supply, according to a White House official, who also cited ongoing U.S. Food and Drug Administration reviews of whether J&amp;J doses may have longer shelf lives. A second administration official said recalling doses that have already been shipped out to vaccination sites to potentially redistribute them would be logistically and legally challenging.<blockquote>据一名白宫官员称，白宫疫苗协调员Bechara Choucair博士已经向州长和地方卫生官员介绍了最大限度供应的最佳做法，他还引用了正在进行的美国疫苗接种。美国食品药品监督管理局审查强生剂量是否可能有更长的保质期。第二位政府官员表示，召回已经运往疫苗接种点的疫苗并可能重新分配将在后勤和法律上具有挑战性。</blockquote> One of the administration officials said most Covid-19 vaccines in the U.S. aren’t close to expiring.<blockquote>一位政府官员说，美国的大多数 Covid-19 疫苗还没有接近过期。</blockquote> State health departments and hospital officials say the guidance from states and the CDC is to destroy or discard expired doses. The CDC didn’t respond to requests for comment.<blockquote>州卫生部门和医院官员表示，各州和疾病预防控制中心的指导是销毁或丢弃过期剂量。疾病预防控制中心没有回应置评请求。</blockquote> In early April, U.S. regulators paused the use of J&amp;J’s vaccine after reports ofrare but severe blood clots. In response, vaccination sites across the country canceled thousands of appointments and instead offered people Pfizer or Moderna doses. Regulators lifted the pause 10 days later, with J&amp;J and regulators adding language to the vaccine’s label warning of a risk of blood clots.<blockquote>4 月初，美国监管机构在报告出现轻微但严重的血栓后暂停了强生疫苗的使用。作为回应，全国各地的疫苗接种点取消了数千个预约，转而向人们提供辉瑞或Moderna剂量。10 天后，监管机构取消了暂停令，强生公司和监管机构在疫苗标签上添加了警告血栓风险的措辞。</blockquote> By then, patient demand for Covid-19 vaccines shifted from mass-vaccination to smaller community settings amid lingering concerns about the rare clots, according to industry and state officials.<blockquote>据行业和州政府官员称，到那时，由于对罕见血栓的持续担忧，患者对 Covid-19 疫苗的需求已从大规模疫苗接种转移到较小的社区环境。</blockquote> The regulatory pause and overall slowdown in vaccinations has left UofL Health in Louisville, Ky., with more than 6,000 J&amp;J doses that expire this month, after having administered about 2,600 since early April, said Dr. Jason Smith, chief medical officer. “My bet is that we will wind up wasting some of that, unfortunately,” he said.<blockquote>监管暂停和疫苗接种的整体放缓使得肯塔基州路易斯维尔的UofL Health离开了。首席医疗官杰森·史密斯博士说，自4月初以来，J&amp;J已经注射了约2600剂，本月将有6000多剂强生疫苗到期。“他说：”我敢打赌，不幸的是，我们最终会浪费其中的一部分。</blockquote> To use them, the health system is trying to reach physician offices outside its network, Dr. Smith said.<blockquote>史密斯博士说，为了使用它们，卫生系统正试图联系其网络之外的医生办公室。</blockquote> Pennsylvania’s Department of Health said it worked with the CDC and Chester County to try to transfer the county’s 50,000 expiring J&amp;J doses to Oregon. The deal fell through when Oregon experienced a decline in demand and no longer wanted them, a Pennsylvania health department spokesman said.<blockquote>宾夕法尼亚州卫生部表示，它与疾病预防控制中心和切斯特县合作，试图将该县即将到期的 5 万剂强生疫苗转移到俄勒冈州。宾夕法尼亚州卫生部发言人说，当俄勒冈州的需求下降，不再需要他们时，这笔交易失败了。</blockquote> The full extent of expiring Covid-19 vaccines is unknown because providers aren’t required to report it to the federal government, said Jessica Daley, a pharmacist and executive atPremierInc.,a large group-purchasing organization for hospitals.<blockquote>大型医院团购机构 PremierInc. 的药剂师兼高管杰西卡-戴利（Jessica Daley）说，到期的 Covid-19 疫苗的全部过期程度尚不清楚，因为供应商无需向联邦政府报告。</blockquote> Premier is asking members whether they have expiring vaccines, and at least a dozen have said they have expiring J&amp;J doses, Ms. Daley said. “It’s not as simple as just moving the vaccine somewhere else,” she said.<blockquote>戴利女士说，总理正在询问成员们是否有即将过期的疫苗，至少有十几个人说他们有即将过期的强生疫苗。“她说：”这不仅仅是把疫苗转移到其他地方那么简单。</blockquote> Some states say they have asked the U.S. government whether doses can be shipped to developing nations. Doing so faces significant logistical and legal hurdles, according to the United Nations Children’s Fund, because those countries are wary of using vaccines after expiration dates and may not be able to administer them quickly.<blockquote>一些州表示，他们已经询问美国政府是否可以向发展中国家运送疫苗。联合国儿童基金会表示，这样做面临着巨大的后勤和法律障碍，因为这些国家对使用过期疫苗持谨慎态度，可能无法快速接种。</blockquote>\n<div class=\"bt-text\">\n\n\n 来源：<a href=\"https://www.wsj.com/articles/millions-of-j-j-covid-19-vaccines-are-at-risk-of-expiring-in-june-11623152775?mod=hp_lead_pos10\">The Wall Street Journal</a>\n为提升您的阅读体验，我们对本页面进行了排版优化\n\n\n</div>\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"JNJ":"强生"},"source_url":"https://www.wsj.com/articles/millions-of-j-j-covid-19-vaccines-are-at-risk-of-expiring-in-june-11623152775?mod=hp_lead_pos10","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1135953958","content_text":"States, hospitals try to reroute such vaccines, while efforts to export them face hurdles.\n\nHospitals, state health departments and the federal government are racing to decide how to use up millions ofJohnson & Johnson’sJNJ-0.68%Covid-19vaccine doses that are set to expire this month.\nThe prospect of so many doses going to waste in the U.S. whendeveloping nations are desperatefor shots would add pressure on the Biden administration to share stockpiled vaccines. But there are few practical solutions to administering them quickly in the U.S. or distributing them in time to foreign countries, according to those involved in the vaccination drive.\nThe stockpile is, in part, an unintended consequence of the U.S.’s decision in April totemporarily suspend administrationof J&J doses to assess a rare blood-clot risk. The pause forced states and providers tocancel large blocksof appointments that were never rescheduled, leaving a surplus of supply, andin some areas increasing hesitancyover the J&J vaccine’s safety, according to industry officials.\nSome hospitals and states say that vaccines fromPfizerInc.and partnerBioNTech SE,as well asModernaInc.,are due to expire later this summer, but the stockpiles so far are largely of J&J doses. Pfizer’s vaccine expires six months after manufacture. Moderna’s vaccine can remain frozen for up to six months, during which it can be refrigerated for one month.\nPhiladelphia has 42,000 J&J doses set to expire, most of which came from a Federal Emergency Management Agency clinic at the city’s convention center a few days before the pause, a city spokesman said. Pennsylvania, West Virginia, Oklahoma and Arkansas are among states that report having thousands of J&J doses set to expire this month and have been unable to redistribute them.\n“There’s no way at the end of June that we’re not going to have a couple thousand expiring,” said Danielle Hilborn, who helps oversee Covid-19 vaccines for McLaren Health Care Corp. The hospital system based outside Flint, Mich., has more than 3,500 J&J doses set to expire this month, despite having moved doses among its hospitals and shipped 1,100 to a county health department.\nHospitals and public-health departments offering the shots have begun special promotions to use J&J’s shots before they go bad. Some health systems have redistributed them inside and outside their networks, and some states have rerouted them to physician offices, pharmacies or other states.\nThe efforts have had limited success because of thenation’s slowdown in overall vaccinationsand because many states and vaccination sites also have expiring J&J supply and don’t see demand for more doses. Just over half of the 21.4 million J&J shots distributed to providers have been administered, according to data from the Centers for Disease Control and Prevention, versus 83% for shots from Moderna Inc. as well as Pfizer Inc. and its partner, BioNTech.\nJ&J stores doses frozen until shipment by the government, at which point they are refrigerated. Doses can be refrigerated for three months, and the drugmaker is studying whether the shelf life can be extended, a company spokesman said.\nMany drugs and vaccines can remain effective for years, but all eventually start to lose potency. Typically, expiring prescription drugs and vaccines for other diseases are sent to other healthcare facilities, overseas or back to manufacturers, hospital officials said.\nCovid-19 vaccines come with expiration information, which is determined by manufacturers based on testing data that is later cleared by regulators. Vaccines may still work after the expiration dates, according to manufacturing experts, but data was limited when the vaccines were authorized.\nThe issue of expiring doses is the latest setback for J&J’s Covid-19 vaccine effort. An accident at a contract manufacturer’s plant led to thecontamination of materialthat could have yielded up to 15 million doses and led to a halt in production of the J&J vaccine there.\nDr. Bechara Choucair, the White House vaccine coordinator, has briefed governors and local health officials on best practices to maximize supply, according to a White House official, who also cited ongoing U.S. Food and Drug Administration reviews of whether J&J doses may have longer shelf lives. A second administration official said recalling doses that have already been shipped out to vaccination sites to potentially redistribute them would be logistically and legally challenging.\nOne of the administration officials said most Covid-19 vaccines in the U.S. aren’t close to expiring.\nState health departments and hospital officials say the guidance from states and the CDC is to destroy or discard expired doses. The CDC didn’t respond to requests for comment.\nIn early April, U.S. regulators paused the use of J&J’s vaccine after reports ofrare but severe blood clots. In response, vaccination sites across the country canceled thousands of appointments and instead offered people Pfizer or Moderna doses. Regulators lifted the pause 10 days later, with J&J and regulators adding language to the vaccine’s label warning of a risk of blood clots.\nBy then, patient demand for Covid-19 vaccines shifted from mass-vaccination to smaller community settings amid lingering concerns about the rare clots, according to industry and state officials.\nThe regulatory pause and overall slowdown in vaccinations has left UofL Health in Louisville, Ky., with more than 6,000 J&J doses that expire this month, after having administered about 2,600 since early April, said Dr. Jason Smith, chief medical officer. “My bet is that we will wind up wasting some of that, unfortunately,” he said.\nTo use them, the health system is trying to reach physician offices outside its network, Dr. Smith said.\nPennsylvania’s Department of Health said it worked with the CDC and Chester County to try to transfer the county’s 50,000 expiring J&J doses to Oregon. The deal fell through when Oregon experienced a decline in demand and no longer wanted them, a Pennsylvania health department spokesman said.\nThe full extent of expiring Covid-19 vaccines is unknown because providers aren’t required to report it to the federal government, said Jessica Daley, a pharmacist and executive atPremierInc.,a large group-purchasing organization for hospitals.\nPremier is asking members whether they have expiring vaccines, and at least a dozen have said they have expiring J&J doses, Ms. Daley said. “It’s not as simple as just moving the vaccine somewhere else,” she said.\nSome states say they have asked the U.S. government whether doses can be shipped to developing nations. Doing so faces significant logistical and legal hurdles, according to the United Nations Children’s Fund, because those countries are wary of using vaccines after expiration dates and may not be able to administer them quickly.","news_type":1,"symbols_score_info":{"JNJ":0.9}},"isVote":1,"tweetType":1,"viewCount":1334,"commentLimit":10,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"symbols":[],"verified":2,"subType":0,"readableState":1,"langContent":"EN","currentLanguage":"EN","warmUpFlag":false,"orderFlag":false,"shareable":true,"causeOfNotShareable":"","featuresForAnalytics":[],"commentAndTweetFlag":false,"andRepostAutoSelectedFlag":false,"upFlag":false,"length":4,"subscribersOnly":false,"subscribersOnlyAccessible":false,"xxTargetLangEnum":"ORIG"},"commentList":[],"isCommentEnd":true,"isTiger":false,"isWeiXinMini":false,"url":"/m/post/117476001"}