迪哲医药(688192.SH)：比瑞替尼治疗弥漫性大B细胞淋巴瘤研究成果获《血液肿瘤期刊》发表

智通财经09-09

智通财经APP讯，迪哲医药(688192.SH)发布公告，公司自主研发的全球首创、可完全穿透血脑屏障的非共价LYN/BTK双靶点抑制剂比瑞替尼(birelentinib)单药治疗复发/难治弥漫性大B细胞淋巴瘤(r/rDLBCL)II期临床研究(TAI-SHAN9)结果正式发表于国际权威血液学期刊《血液肿瘤期刊》(Blood Cancer Journal，影响因子：13.8)。

比瑞替尼是一款全球首创的LYN/BTK双靶点抑制剂，旨在通过同时阻断 BTK 依赖和BTK非依赖的BCR信号通路，实现对不同DLBCL亚型的广谱覆盖。

TAI-SHAN9研究入组患者既往接受过1至5线系统性治疗。研究结果显示，在50mg和75mg剂量下，比瑞替尼单药治疗在不同分子亚型中均展现出广谱的抗肿瘤活性，并呈现出可管理的安全性。

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