石药集团：SYS6063用于治疗SLE的Ⅰ期临床试验在中国首家中心正式启动

第一财经08-11 20:17

石药集团在港交所公告，公司开发的SYS6063用于治疗复发难治性系统性红斑狼疮（SLE）的Ⅰ期临床试验已在中国首家中心正式启动。该产品为目前全球首款获批开展SLE临床试验的基于LNP-mRNA转染的靶向CD19/BCMA的嵌合抗原受体T细胞（CAR-T）产品。该产品采用脂质纳米颗粒（LNP）将表达CD19和BCMA的CAR mRNA转染入T细胞，使其同步表达两个完整的CAR蛋白，从而有效杀伤分泌...

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