百济神州：公司已停止原Pan-KRAS抑制剂BGB-53038的开发，但并未退出RAS赛道

证券日报 08-07

证券日报网8月7日讯，百济神州在接受调研时表示，公司已停止原Pan-KRAS抑制剂BGB-53038的开发，但并未退出RAS赛道。新项目为Pan-RAS分子胶降解剂，与Revolution Medicines的产品类似，但具有包括更高效的KRAS降解、更长且更平稳的PK（可能转化为更好的安全性）以及较好的血脑屏障穿透能力等潜在差异化优势，而后者对脑转移发生率较高的非小细胞肺癌具有潜在意义。

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