诺诚健华盘中涨超9% 自研靶向CDH17的新型ADC创新药ICP-B208完成首例患者给药

新浪港股07-06 09:52

热点栏目自选股数据中心行情中心资金流向模拟交易

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　　诺诚健华（09969）盘中涨超9%，截至发稿，股价上涨6.42%，现报13.92港元，成交额5426.90万港元。

　　7月6日，据诺诚健华官微消息，公司宣布自主研发的靶向CDH17的新型ADC创新药ICP-B208完成首例患者给药。基于诺诚健华自主研发的ADC技术平台，ICP-208由人源化抗CDH17抗体通过蛋白酶可裂解连接子与公司自主开发的强效有效载荷偶联而成，可精准靶向肿瘤细胞，同时最大限度减少脱靶效应。

　　据介绍，CDH17属钙黏蛋白家族，在肿瘤细胞增殖、迁移与转移过程中发挥关键作用，且在结直肠癌、胃癌、胰腺癌及胆道癌等多种消化道实体瘤中呈现特异性高表达，已成为全球ADC领域极具潜力的新兴靶点之一。目前，全球尚无CDH17靶向ADC新药上市。

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