“百万元一针”抗癌药有望降至万元，科济药业研发通用型CAR-T疗法

上观新闻06-22 14:57

　　科济药业创始人、首席执行官李宗海博士介绍，科济药业已将研发重心从自体CAR-T（嵌合抗原受体T细胞）转向通用型CAR-T疗法。

　　自体CAR-T疗法利用人体自身免疫系统开展个体化治疗：先通过白细胞分离，从患者体内提取 T 细胞；再用CAR（嵌合抗原受体）对其修饰，让T细胞能识别癌细胞上特定抗原；完成基因工程修饰后，将CAR-T制剂回输给这名患者。

　　通用型CAR-T疗法不是从患者本人，而是从健康志愿者的外周血里提取T细胞，再以此为原料，批量化生产CAR-T。与定价高达上百万元的自体CAR-T疗法相比，通用型CAR-T的生产成本只有其几十分之一，未来如获批上市，将大幅提升CAR-T疗法的普惠性。而且，病人不再需要抽血后等一个月再回输，就诊后即可输注“现货”。

（文章来源：上观新闻）

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