石药集团一项创新研究成果在ACS Org. Process Res. Dev.发表

第一财经04-30 08:47

据石药集团消息，近日，由石药集团研发的基于在线红外光谱技术用于寡核苷酸固相合成脱保护工艺优化的研究成果以研究论文（Article）形式发表在国际著名化学期刊ACS旗下Org. Process Res. Dev.杂志。该研究首次利用在线红外光谱技术，系统识别并确定了寡核苷酸固相脱三苯甲基化的最佳工艺节点与工艺范围，通过对脱保护试剂中二氯乙酸单聚体、二氯乙酸二聚体、甲苯、乙腈特征红外峰的鉴别与动力学...

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