中国生物制药(01177)与Sanofi就罗伐昔替尼订立独家授权协议

智通财经03-04

智通财经APP讯，中国生物制药(01177)公布，集团附属公司正大天晴药业集团股份有限公司(正大天晴)已与Sanofi S.A.的一间全资附属公司(Sanofi)就集团的JAK/ROCK抑制剂罗伐昔替尼在全球的开发、生产及商业化订立独家授权协议。根据协议条款，该集团将授予Sanofi在全球范围内开发、生产及商业化罗伐昔替尼的独家许可。集团有权获得1.35亿美元的首付款、以及最高13.95亿美元的...

网页链接

免责声明：本文观点仅代表作者个人观点，不构成本平台的投资建议，本平台不对文章信息准确性、完整性和及时性做出任何保证，亦不对因使用或信赖文章信息引发的任何损失承担责任。

精彩评论

我们需要你的真知灼见来填补这片空白

发表看法

{"i18n":{"language":"zh_CN"},"isChannel":false,"data":{"share":"https://www.laohu8.com/m/news/2616774663?lang=zh_CN&edition=full","thumbnail":"","is_english":false,"pubTime":"2026-03-04 06:19","share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","id":"2616774663","market":"hk","top_or_hot":-1,"title":"中国生物制药(01177)与Sanofi就罗伐昔替尼订立独家授权协议","media":"智通财经","content":"<div>\n<p>智通财经APP讯，中国生物制药(01177)公布，集团附属公司正大天晴药业集团股份有限公司(正大天晴)已与Sanofi S.A.的一间全资附属公司(Sanofi)就集团的JAK/ROCK抑制剂罗伐昔替尼在全球的开发、生产及商业化订立独家授权协议。根据协议条款，该集团将授予Sanofi在全球范围内开发、生产及商业化罗伐昔替尼的独家许可。集团有权获得1.35亿美元的首付款、以及最高13.95亿美元的...</p>\n\n<a href=\"http://www.zhitongcaijing.com/content/detail/1409708.html\">网页链接</a>\n\n</div>\n","source":"stock_zhitongcaijing","html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>中国生物制药(01177)与Sanofi就罗伐昔替尼订立独家授权协议</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n中国生物制药(01177)与Sanofi就罗伐昔替尼订立独家授权协议\n</h2>\n\n<h4 class=\"meta\">\n\n\n2026-03-04 06:19 北京时间&nbsp;&nbsp;&nbsp;<a href=http://www.zhitongcaijing.com/content/detail/1409708.html><strong>智通财经</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>智通财经APP讯，中国生物制药(01177)公布，集团附属公司正大天晴药业集团股份有限公司(正大天晴)已与Sanofi S.A.的一间全资附属公司(Sanofi)就集团的JAK/ROCK抑制剂罗伐昔替尼在全球的开发、生产及商业化订立独家授权协议。根据协议条款，该集团将授予Sanofi在全球范围内开发、生产及商业化罗伐昔替尼的独家许可。集团有权获得1.35亿美元的首付款、以及最高13.95亿美元的...</p>\n\n<a href=\"http://www.zhitongcaijing.com/content/detail/1409708.html\">网页链接</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK1515","symbol_name":"抗疫概念","start_time":0,"source_url":"http://www.zhitongcaijing.com/content/detail/1409708.html","article_id":"2616774663","we_media_id":null,"thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2616774663","pubTimestamp":1772576365,"columns":[],"sourceInfo":{"source_id":"stock_zhitongcaijing","name":"智通财经网"},"weMediaInfo":null,"summary":"智通财经APP讯，中国生物制药 公布，集团附属公司正大天晴药业集团股份有限公司已与Sanofi S.A.的一间全资附属公司就集团的JAK/ROCK抑制剂罗伐昔替尼在全球的开发、生产及商业化订立独家授权协议。根据协议条款，该集团将授予Sanofi在全球范围内开发、生产及商业化罗伐昔替尼的独家许可。","collect":0,"end_time":0,"defaultTopTitle":"zhitongcaijing.com","property":[],"viewcount":null,"language":"zh","relate_stocks":{"BK1515":"抗疫概念","BK1191":"制药","IE00BZ08YR35.GBP":"GUINNESS BEST OF CHINA \"C\" (GBP) ACC","IE00BZ08YT58.USD":"GUINNESS BEST OF CHINA \"C\" (USD) ACC","GCVRZ":"Sanofi","BK1521":"挪威政府全球养老基金持仓","SNYNF":"Sanofi","BK4007":"制药","IE00BZ08YS42.EUR":"GUINNESS BEST OF CHINA \"C\" (EUR) ACC","01177":"中国生物制药","BK1589":"北水核心资产","HK0000165453.HKD":"华夏精选大中华科技基金 A类港币"},"translate_title":"Sinopharmaceuticals (01177) entered into an exclusive licensing agreement with Sanofi for rovacitinib","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"GCVRZ":1.5,"SNYNF":1.5,"01177":1.5},"content_text":"智通财经APP讯，中国生物制药(01177)公布，集团附属公司正大天晴药业集团股份有限公司(正大天晴)已与Sanofi S.A.的一间全资附属公司(Sanofi)就集团的JAK/ROCK抑制剂罗伐昔替尼在全球的开发、生产及商业化订立独家授权协议。根据协议条款，该集团将授予Sanofi在全球范围内开发、生产及商业化罗伐昔替尼的独家许可。集团有权获得1.35亿美元的首付款、以及最高13.95亿美元的潜在开发、监管及销售里程碑付款，同时还将获得基于罗伐昔替尼年度净销售额的最高双位数的阶梯式特许权使用费。协议的生效以惯常的交割条件为前提，包括取得相关监管部门的批准。据悉，罗伐昔替尼是一款全球首创(First-in-Class)的新型、强效口服小分子JAK/ROCK抑制剂，通过双通路协同实现抗炎与抗纤维化。一方面，它靶向JAK/STAT通路，直接阻断炎症信号传导，从源头减少髓系细胞产生的炎症因子;另一方面，它靶向ROCK通路，通过调节STAT3/STAT5磷酸化来下调过度活化的T辅助细胞(Th17)、增强调节性T细胞(Treg)功能，从而重建免疫平衡。2026年2月，罗伐昔替尼(商品名：安煦® )已获得中国国家药品监督管理局(NMPA)批准上市，用于中危-2或高危的塬发性⻣髓纤维化 (PMF)、真性红细胞增多症后⻣髓纤维化(PPV-MF) 或塬发性血小板增多症后⻣髓纤维化 (PET-MF) 成年患者的一线治疗。此外，罗伐昔替尼在慢性移植物抗宿主病 (cGVHD) 治疗领域亦展现出突破性潜力：在中国已进入 III期临床试验阶段，并于2025年8月被CDE纳入突破性治疗药物程序;在美国已获准开展II期临床研究。其治疗cGVHD的Ib/IIa期临床数据已发表于《Blood》期刊，研究显示，与其他已获批疗法相比，罗伐昔替尼的12个月无失败生存率(FFS)表现更优，且在纤维化主导的器官中展现出更强的治疗应答，并具有克服芦可替尼耐药的潜力。","kind":"news","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"corporation","news_rank":0,"isVideo":false,"video":null,"symbols":[],"gpt_button":1,"need_auth":false,"need_login_tip":false,"code":"91000000","status":"200"},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":false,"tenantId":"TBCN","deviceId":"web-server-community-laohu8-v3","version":"4.42.1","shortVersion":"4.42.1","platform":"web","vendor":"web","appName":"laohu8","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2616774663","isCrawlerRequest":true}