释放pipeline in a drug潜力 NLRP3能否催生下一个“药王”?

智通财经网02-05

生物医药领域的管线开发决策，往往是创新性、可行性、投入产出比等因素的多维平衡。其中，“pipeline in a drug”是一种极具吸引力的策略：通过同一药物覆盖多种适应症，形成可持续扩展的商业与临床价值。阿达木单抗、帕博利珠单抗(K药)等“药王”正是这一策略的典型代表。NOD样受体蛋白3(NLRP3)作为长期被验证的抗炎靶点，可介导促炎细胞因子IL‑1β与IL‑18释放，并处于炎症级联反应的...

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