恒瑞医药新型口服小分子GLP-1受体激动剂HRS-7535用于高血压合并超重或肥胖获批Ⅲ期临床

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近日，恒瑞医药子公司山东盛迪医药有限公司收到国家药品监督管理局核准签发的《药品临床试验批准通知书》，同意公司自主研发的1类创新口服小分子GLP-1受体激动剂HRS-7535片开展用于高血压合并超重或肥胖适应症的Ⅲ期临床研究。高血压和肥胖已成为全球公共卫生的重大挑战，两者常并存且相互促进，显著增加心血管疾病、代谢综合征和靶器官损害的风险。据世界卫生组织（WHO）统计，全球高血压患者已超过13亿，其中...

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Hypertension [Internet]. Geneva: WHO; 2023 [cited 2024 Jun 20]. Available from: https://www.who.int/health-topics/hypertension[2] Wang Z, Chen Z, Zhang L, Wang X, Hao G, Zhang Z, et al. Status of hypertension in China: results from the China Hypertension Survey, 2012-2015. Lancet. 2018;392(10159):2052-90.[3]中国高血压防治指南(2024年修订版)，中华高血压杂志 2024 Vol. 32 Issue 7 Pages 603-700[4]GLP-1 Agonists and Blood Pressure: A Review of the Evidence. Curr Hypertens Rep 2016 Vol. 18 Issue 2 Pages 16声明：1. 本新闻旨在分享研发前沿资讯，仅供医疗卫生专业人士参阅，非广告用途。2. 恒瑞医药不推荐任何未被批准的药品、适应症的使用。","kind":"news","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"dataReport","news_rank":0,"symbols":[],"gpt_button":1,"need_auth":false,"code":"91000000","status":"200"},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":false,"tenantId":"TBCN","deviceId":"web-server-community-laohu8-v3","version":"4.36.2","shortVersion":"4.36.2","platform":"web","vendor":"web","appName":"laohu8","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2607754110","isCrawlerRequest":true}