8000万美元种子轮！英伟达，投了一家AI制药！牵手强生、BMS，今年进入临床！

智药局01-19

近日，AI制药公司Proxima（前身为VantAI）宣布完成了超额认购的8000万美元（约合人民币5.5亿元）种子轮，本轮融资由DCVC主导，参与者包括英伟达的风险投资部门NVentures、被称为创新药“捡漏王”的Roivant等。这家公司主打AI驱动的邻近式疗法（proximity therapeutics），这类疗法通过控制蛋白质之间的相互作用来工作，而不仅仅是抑制或激活单一靶点，代表类型...

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Nvidia, invested in an AI pharmaceutical company! Join hands with Johnson & Johnson and BMS to enter the clinic this year!","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"NVD3.UK":0.6,"NVDW":0.6,"NVDX":0.6,"NVDD":0.6,"NVDS.UK":0.6,"NVIW.SI":0.6,"NVII":0.6,"DIPS":0.6,"NVD2.UK":0.6,"3NVD.UK":0.6,"NVD":0.6,"NVDG":0.6,"NVDA":0.9,"2NVD.UK":0.6,"NVDY":0.6,"SNVD.UK":0.6,"NVDS":0.6,"NVDU":0.6,"NVDQ":0.6},"content_text":"近日，AI制药公司Proxima（前身为VantAI）宣布完成了超额认购的8000万美元（约合人民币5.5亿元）种子轮，本轮融资由DCVC主导，参与者包括英伟达的风险投资部门NVentures、被称为创新药“捡漏王”的Roivant等。这家公司主打AI驱动的邻近式疗法（proximity therapeutics），这类疗法通过控制蛋白质之间的相互作用来工作，而不仅仅是抑制或激活单一靶点，代表类型有分子胶、PROTAC等。本轮融资将加速首创邻近式疗法的进展，扩大可药物靶点空间，并促进肿瘤学、免疫学及其他疾病领域更可靠地发现新机制。牵手强生、BMS 瞄准难成药靶点生物过程由蛋白质-蛋白质相互作用介导，但其中只有不到5%的相互作用被结构性表征，绝大多数人类相互作用组尚未被探索。Proxima关注到背后的市场潜力，并提出“让蛋白质相互作用可编程化”的目标。Proxima的核心技术之一是NeoLink数据生成技术，能够在蛋白质组范围内生成蛋白质复合物的结构信息，以结合其Neo AI模型系列。这一些系列的首个模型Neo-1是全球首个解码和设计生命结构的模型，能将最先进的结构预测和全原子分子生成整合到一个统一的模型中。这些系统共同实现了近距离调制小分子的端到端发现和开发，目标是提高安全性、缩短时间线，并实现全新的治疗机制，以应对此前“无法下药”的难题靶点。目前，Proxima已经与强生、百时美施贵宝和Blueprint Medicines（被赛诺菲收购）等领导者建立了数十亿美元的研究合作，首个项目预计于2026年进入临床试验阶段。推荐阅读","kind":"news","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"2","news_tag":"corporation","news_rank":0,"isVideo":false,"video":null,"symbols":[],"gpt_button":0,"need_auth":false,"need_login_tip":false,"code":"91000000","status":"200"},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":false,"tenantId":"TBCN","deviceId":"web-server-community-laohu8-v3","version":"4.42.0","shortVersion":"4.42.0","platform":"web","vendor":"web","appName":"laohu8","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2604138134","isCrawlerRequest":true}