【拔萃资本｜投资企业新闻】CytoReason发布AI Agent LINA，加速制药研发中的计算生物学应用

拔萃资本01-13

在2026年摩根大通医疗健康大会(JP Morgan Healthcare Conference)上，CytoReason发布了面向制药研发的AI Agent——LINA。LINA定位为一款计算生物学助手，基于CytoReason自研的AI疾病模型，并结合NVIDIA NIM微服务，对分子层面、临床数据及患者级别信息进行系统化解读。依托CytoReason的AI框架，并在制药行业数百个真实药物开发...

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and development","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"NVDD":0.6,"2NVD.UK":0.6,"NVD":0.6,"NVDA":1.61,"NVDX":0.6,"NVD3.UK":0.6,"NVDU":0.6,"NVD2.UK":0.6,"SNVD.UK":0.6,"NVDS.UK":0.6,"AI":0.88,"NVDY":0.6,"NVDS":0.6,"NVIW.SI":0.6,"3NVD.UK":0.6},"content_text":"在2026年摩根大通医疗健康大会(JP Morgan Healthcare Conference)上，CytoReason发布了面向制药研发的AI Agent——LINA。LINA定位为一款计算生物学助手，基于CytoReason自研的AI疾病模型，并结合NVIDIA NIM微服务，对分子层面、临床数据及患者级别信息进行系统化解读。依托CytoReason的AI框架，并在制药行业数百个真实药物开发问题上完成训练，LINA能够给出具备可验证性的分析方案，生成可复现的分析代码，并在基因、信号通路、细胞类型及患者亚组等多个层面提供清晰的生物学解释。由于所有输出均锚定在机制型疾病模型之上，LINA有效规避了通用大语言模型中常见的“幻觉”问题。在技术架构上，LINA运行于NVIDIA加速计算平台，并采用以NVIDIA NIM微服务形式托管的Qwen3-Next-80B-A3B-Instruct模型，实现了快速推理、安全部署，并可无缝接入现有研发系统，从而支持制药研发团队以更高效率、在更大规模下完成复杂生物学分析。目前，CytoReason正与多家全球领先的制药公司合作，对LINA的实际能力进行验证。公司与武田制药(Takeda)在欧洲胃肠病学联合大会(UEG Congress)上发表的研究数据显示，TYK2依赖的基因特征富集与溃疡性结肠炎及克罗恩病均存在显著相关性，该成果也体现了LINA在靶点发现层面的应用潜力。在此基础上，LINA使研究人员能够以对话方式深入探索疾病生物学，大幅缩短分析周期，并在研发过程中的多个关键节点支持更高质量、更具确定性的决策。同时，LINA 还能自动生成可视化结果、研究摘要及端到端分析报告，进一步简化研发流程，提升循证决策效率。随着制药企业持续扩展其AI体系，LINA也为可扩展的多智能体科学工作流奠定了基础，有望进一步提升研发决策的速度、准确性与透明度。CytoReason联合创始人兼首席科学官Shai Shen-Orr教授表示：“CytoReason的目标，是构建生物智能的计算基础设施，而LINA正是这一愿景的具体体现。通过将计算型疾病模型、分子与临床数据以及先进的AI基础设施有机结合，LINA让科学家能够直接与疾病生物学展开交互，获得有生物学依据的答案。我们很高兴能与NVIDIA以及武田等合作伙伴携手，将这一技术落地，并推动研发决策方式的变革。”关于CytoReason2021年6月，拔萃创新科技 I 期基金于参与了CytoReason的A轮融资。2024年7月，CytoReason完成8,000万美元的B轮融资，投资人包括英伟达、辉瑞、赛诺菲等。CytoReason是一家以色列创新医疗技术公司，成立于 2016年 10月，主要专注于使用其 AI技术平台来研发多种疾病疗法，覆盖癌症、自身免疫疾病、神经退行疾病和传染病等领域。公司目前正开发基于细胞层面的人体疾病计算模型，并通过与辉瑞等制药公司合作，获取大量的临床数据来训练其 AI模型，不断提高模型预测的准确性。借助于CytoReason庞大数据库和AI技术平台，生物制药及生物技术公司有望显著缩短药物发现和研发时间，降低新药研发成本并增加药物获批的可能性。迄今为止，公司已与辉瑞、赛诺菲、葛兰素史克、强生、罗氏等全球领先的跨国药企达成合作。","kind":"news","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"productRelease","news_rank":0,"isVideo":false,"video":null,"symbols":[],"gpt_button":0,"need_auth":false,"need_login_tip":false,"code":"91000000","status":"200"},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; 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