张卓莉教授：泰它西普中国III期研究数据发布，重塑干燥综合征治疗格局

动脉网2025-12-06

干燥综合征缺乏有效靶向药，临床管理以缓解局部症状为主，生物制剂带来新希望。近日，泰它西普治疗干燥综合征的中国Ⅲ期临床研究数据公布，该随机、双盲、安慰剂对照试验显示，泰它西普160mg组第24周ESSDAI评分较基线显著降低4.4分，疗效持续至48周（降低4.6分），与安慰剂组相比降幅显著更大，组间差值分别为3.8分和4.2分（均P<0.0001），所有次要终点和其他终点也均显著改善。这一成果证实...

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