第一三共公布TROPION-Breast02 Ⅲ期研究积极的主要结果

格隆汇2025-10-07

据第一三共消息，TROPION-Breast02 Ⅲ期研究公布了积极的主要结果：德达博妥单抗在总生存期（OS）和无进展生存期（PFS）双主要终点上统计学差异具有显著性并取得临床意义的改善。该研究比较了德达博妥单抗与研究者选择的化疗方案，用于不适合抗PD-1/PD-L1治疗的局部复发不可手术或转移性三阴性乳腺癌（TNBC）患者的一线治疗。德达博妥单抗是一款靶向TROP2的DXd抗体偶联药物（ADC）...

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