赛诺菲(SNY.US)全球首创OX40L单抗III期研究成功

智通财经网09-04

智通财经APP获悉，9月4日，赛诺菲(SNY.US)宣布Amlitelimab治疗特应性皮炎的III期COAST 1研究达到了所有主要终点和次要终点。Amlitelimab是赛诺菲开发的一款靶向OX40L(OX40配体)的全人源非T细胞耗竭性单克隆抗体，可阻断关键免疫调节因子OX40L与其受体OX40结合，并保持促炎性T细胞和调节性T细胞之间的平衡，进而起到治疗特应性皮炎、哮喘、化脓性汗腺炎等...

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