强生(JNJ.US)/艾伯维(ABBV.US)遇劲敌！礼来(LLY.US)BTK抑制剂三期临床达主要终点

智通财经2025-07-29

智通财经APP获悉，礼来(LLY.US)周二宣布，其经美国食品药品监督管理局(FDA)批准的布鲁顿酪氨酸激酶抑制剂Jaypirca在针对慢性淋巴细胞白血病(CLL)或小淋巴细胞淋巴瘤(SLL)患者的三期头对头临床试验中，达到了主要研究终点，成功挑战了强生(JNJ.US)与艾伯维(ABBV.US)的同类重磅药物Imbruvica。这项名为BRUIN CLL-314的三期研究直接比较了Jaypirca...

网页链接

免责声明：本文观点仅代表作者个人观点，不构成本平台的投资建议，本平台不对文章信息准确性、完整性和及时性做出任何保证，亦不对因使用或信赖文章信息引发的任何损失承担责任。

精彩评论

我们需要你的真知灼见来填补这片空白

发表看法

{"i18n":{"language":"zh_CN"},"isChannel":false,"data":{"share":"https://www.laohu8.com/m/news/2555054519?lang=zh_CN&edition=full","thumbnail":"","is_english":false,"pubTime":"2025-07-29 21:32","share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","id":"2555054519","market":"fut","top_or_hot":-1,"title":"强生(JNJ.US)/艾伯维(ABBV.US)遇劲敌！礼来(LLY.US)BTK抑制剂三期临床达主要终点","media":"智通财经","content":"<div>\n<p>智通财经APP获悉，礼来(LLY.US)周二宣布，其经美国食品药品监督管理局(FDA)批准的布鲁顿酪氨酸激酶抑制剂Jaypirca在针对慢性淋巴细胞白血病(CLL)或小淋巴细胞淋巴瘤(SLL)患者的三期头对头临床试验中，达到了主要研究终点，成功挑战了强生(JNJ.US)与艾伯维(ABBV.US)的同类重磅药物Imbruvica。这项名为BRUIN CLL-314的三期研究直接比较了Jaypirca...</p>\n\n<a href=\"http://www.zhitongcaijing.com/content/detail/1323307.html\">网页链接</a>\n\n</div>\n","source":"stock_zhitongcaijing","html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>强生(JNJ.US)/艾伯维(ABBV.US)遇劲敌！礼来(LLY.US)BTK抑制剂三期临床达主要终点</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n强生(JNJ.US)/艾伯维(ABBV.US)遇劲敌！礼来(LLY.US)BTK抑制剂三期临床达主要终点\n</h2>\n\n<h4 class=\"meta\">\n\n\n2025-07-29 21:32 北京时间&nbsp;&nbsp;&nbsp;<a href=http://www.zhitongcaijing.com/content/detail/1323307.html><strong>智通财经</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>智通财经APP获悉，礼来(LLY.US)周二宣布，其经美国食品药品监督管理局(FDA)批准的布鲁顿酪氨酸激酶抑制剂Jaypirca在针对慢性淋巴细胞白血病(CLL)或小淋巴细胞淋巴瘤(SLL)患者的三期头对头临床试验中，达到了主要研究终点，成功挑战了强生(JNJ.US)与艾伯维(ABBV.US)的同类重磅药物Imbruvica。这项名为BRUIN CLL-314的三期研究直接比较了Jaypirca...</p>\n\n<a href=\"http://www.zhitongcaijing.com/content/detail/1323307.html\">网页链接</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"JNJ","symbol_name":"强生","start_time":0,"source_url":"http://www.zhitongcaijing.com/content/detail/1323307.html","article_id":"2555054519","we_media_id":null,"thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2555054519","pubTimestamp":1753795966,"columns":[],"sourceInfo":{"source_id":"stock_zhitongcaijing","name":"智通财经网"},"weMediaInfo":null,"summary":"智通财经APP获悉，礼来周二宣布，其经美国食品药品监督管理局批准的布鲁顿酪氨酸激酶抑制剂Jaypirca在针对慢性淋巴细胞白血病或小淋巴细胞淋巴瘤患者的三期头对头临床试验中，达到了主要研究终点，成功挑战了强生与艾伯维的同类重磅药物Imbruvica。这项名为BRUIN CLL-314的三期研究直接比较了Jaypirca与Imbruvica在初诊或未接受过BTK抑制剂治疗的CLL/SLL患者中的疗效。目前，Jaypirca与Imbruvica均是美国FDA批准的口服靶向药物，获批适应症包括CLL和SLL等血液系统恶性肿瘤。","collect":0,"end_time":0,"defaultTopTitle":"zhitongcaijing.com","property":[],"viewcount":null,"language":"zh","relate_stocks":{"JNJ":"强生","LU2237438978.USD":"Amundi Funds US Pioneer A2 (C) USD","LU2324357040.USD":"HSBC GIF GLOBAL EQUITY SUSTAINABLE HEALTHCARE \"AC\" (USD) ACC","LU2430703178.SGD":"WELLINGTON MULTI-ASSET HIGH INCOME \"AM4H\" (SGDHDG) INC","SG9999015986.USD":"LIONGLOBAL DISRUPTIVE INNOVATION \"I\" (USD) ACC","LU1868837300.USD":"CT (LUX) I AMERICAN FUND \"9\" (USD) ACC","LU0266013472.USD":"AXA WF - Framlington Longevity Economy A Cap USD","LU1093756325.SGD":"FTIF - Franklin K2 Alt Strat Fd A (acc) SGD-H1","BK4585":"ETF&股票定投概念","LU1989772923.USD":"CPR Invest - Climate Action A2 Acc USD-H","LU2237443895.HKD":"abrdn SICAV I -  GLOBAL DYNAMIC DIVIDEND \"A\" (HKD) ACC","LU2236285917.USD":"ALLIANZ GLOBAL INCOME \"AMG\" (USD) INC","LU1430594728.SGD":"Eastspring Investments - Global Low Volatility Equity AS SGD","LU1934455277.USD":"AB SICAV I LOW VOLATILITY TOTAL RETURN EQUITY PORT \"AD\" (USD) INC","LU0320765059.SGD":"FTIF - Franklin US Opportunities A Acc SGD","IE00BJT1NW94.SGD":"JANUS HENDERSON GLOBAL LIFE SCIENCES \"A2\" (SGDHDG) ACC","SG9999014898.SGD":"United Global Quality Growth Fund Dis SGD","LU0323591593.USD":"SCHRODER ISF QEP GLOBAL QUALITY \"A\" (USD) ACC","IE00BVYPNV92.GBP":"GUINNESS GLOBAL EQUITY INCOME \"C\" (GBP) ACC","LU1003077747.HKD":"BGF GLOBAL EQUITY INCOME \"A6\" (HKDHDG) INC","SG9999018865.SGD":"United Global Quality Growth Fd Cl Dist SGD-H","LU2112291526.USD":"BGF WORLD HEALTHSCIENCE \"A4\" (USD) INC","LU0170899867.USD":"EASTSPRING INVESTMENTS WORLD VALUE EQUITY  \"A\" (USD) ACC","LU0820561818.USD":"安联收益及增长平衡基金Cl AM DIS","LU0256863902.USD":"ALLIANZ US EQUITY \"AT\" (USD) ACC","LU1127390331.HKD":"AB SICAV I - ALL MARKET INCOME PORTFOLIO \"A\" (HKD) ACC","LU2361044949.HKD":"WELLINGTON US QUALITY GROWTH \"A\" (HKD) ACC","LLY":"礼来","BK4568":"美国抗疫概念","LU0882574139.USD":"富达环球消费行业基金A ACC","LU2347655156.SGD":"JPMorgan Investment Funds - Global Income A (icdiv) SGD-H","LU0795875086.SGD":"JPMorgan Investment Funds - Global Income A (div) SGD","LU2462157665.USD":"ALLIANZ GLOBAL INCOME \"A\" (USD) INC","LU1244550494.USD":"FRANKLIN GLOBAL MULTI-ASSET INCOME \"A\" (USDHEDGED) ACC","LU0640476718.USD":"THREADNEEDLE (LUX) US CONTRARIAN CORE EQ \"AU\" (USD) ACC","LU0211328371.USD":"TEMPLETON GLOBAL EQUITY INCOME \"A\" (MDIS) (USD)   INC","LU0320765992.SGD":"FTIF - Franklin Biotechnology Discovery A Acc SGD","SG9999015978.USD":"利安颠覆性创新基金A","SGXZ51526630.SGD":"大华环球创新基金A Acc SGD","LU0345769128.USD":"NINETY ONE GSF GLOBAL EQUITY \"A\" (USD) ACC","LU2471134796.USD":"INVESCO GLOBAL EQUITY INCOME ADVANTAGE \"A\" (USD) INC","LU0109394709.USD":"富兰克林生物科技新领域基金A (acc)","LU0823416689.USD":"BNP PARIBAS HEALTH CARE INNOVATORS \"C\" (USD) ACC","IE00B1BXHZ80.USD":"Legg Mason ClearBridge - US Appreciation A Acc USD","LU0861579265.USD":"联博低波幅策略股票基金A","LU1935042991.SGD":"MANULIFE GF GLOBAL MULTI-ASSET DIVERSIFIED INCOME  \"AA\" (SGDHDG) INC","LU2129689431.USD":"FRANKLIN GLOBAL INCOME \"A\" (USD) ACC","ABBV":"艾伯维公司","LU2360106947.USD":"BGF NUTRITION \"A4\" (USD) INC","LU1291159041.SGD":"CPR Invest - Global Silver Age A2 Acc SGD-H"},"translate_title":"Johnson & Johnson (JNJ.US)/AbbVie (ABBV.US) meets a strong rival! Eli Lilly (LLY.US) BTK inhibitor phase III clinical trial reached primary endpoint","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"JNJ":1,"ABBV":1,"LLY":1},"content_text":"智通财经APP获悉，礼来(LLY.US)周二宣布，其经美国食品药品监督管理局(FDA)批准的布鲁顿酪氨酸激酶抑制剂Jaypirca在针对慢性淋巴细胞白血病(CLL)或小淋巴细胞淋巴瘤(SLL)患者的三期头对头临床试验中，达到了主要研究终点，成功挑战了强生(JNJ.US)与艾伯维(ABBV.US)的同类重磅药物Imbruvica。这项名为BRUIN CLL-314的三期研究直接比较了Jaypirca(吡妥布替尼)与Imbruvica(伊布替尼)在初诊或未接受过BTK抑制剂治疗的CLL/SLL患者中的疗效。根据公布的顶线数据，吡妥布替尼在总体缓解率(ORR)方面展现出统计学优势，无论是针对预先治疗组还是意向治疗人群，均达到非劣效性主要终点。礼来指出，虽然无进展生存期(PFS)这一次要终点的数据尚未成熟，但已显示出有利于吡妥布替尼的趋势。这家总部位于印第安纳州的制药巨头表示，后续分析将进一步验证PFS优势。在安全性方面，Jaypirca的表现与既往研究结果一致。公司计划在今年晚些时候的医学会议上公布详细数据。目前，Jaypirca与Imbruvica均是美国FDA批准的口服靶向药物，获批适应症包括CLL和SLL等血液系统恶性肿瘤。","kind":"news","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"2","news_tag":"productRelease","news_rank":0,"isVideo":false,"video":null,"symbols":[],"gpt_button":0,"need_auth":false,"need_login_tip":false,"code":"91000000","status":"200"},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":1,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":false,"tenantId":"TBCN","deviceId":"web-server-community-laohu8-v3","version":"4.43.1","shortVersion":"4.43.1","platform":"web","vendor":"web","appName":"laohu8","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2555054519","isCrawlerRequest":true}