百济潜在 BIC 蛋白降解剂获批新临床

Insight数据库2025-07-23

7 月 23 日，CDE 官网显示，百济神州BGB-45035 片获批临床，用于治疗类风湿性关节炎。这是继特应性皮炎和结节性痒疹后，BGB-45035 获批的第三项临床。来源：CDE 官网BGB-45035 是一款靶向白细胞介素 1 受体相关激酶4（IRAK4）的蛋白降解剂（CDAC）。据百济介绍，BGB-45035 具有同类最佳（BIC）潜力，在临床前模型中，相比 KT474，BGB-...

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