翰森制药：公开B7H3 ADC、B7H4 ADC分子结构

药渡2025-07-18

▎Armstrong2025年7月，翰森制药B7H3 ADC、B7H4 ADC新药的分子结构正式公开。翰森制药B7H3 ADC新药HS-20093通用名为Risvutatug rezetecan，目前处于三期临床阶段。HS-20093的氨基酸序列如下，毒素采用恒瑞的SHR-9265（rezetecan），DAR值为4。HS-20093此前拿下非小细胞肺癌、小细胞肺癌、骨肉瘤的突破疗法。翰森制药...

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