加科思-B(01167)完成泛KRAS抑制剂JAB-23E73 I/IIa期临床试验在美国的首例患者给药

智通财经2025-07-02

智通财经APP讯，加科思-B(01167)发布公告，公司自主研发的泛KRAS抑制剂JAB-23E73在美国完成I/IIa期临床试验首例患者给药。目前该药物在中国的剂量递增研究也正按计划顺利推进。KRAS是最常导致致癌突变的基因之一，约23%-25%的癌症患者带有KRAS突变，其在胰腺癌(约90%)、结直肠癌(约40%)和非小细胞肺癌(约30%)中突变频率尤为显著。全球每年新增约270万患有KRAS...

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