诺和诺德长效生长激素III期研究成功；默沙东新型抗菌药物锐可博在华上市

Ofweek维科网2025-05-13

诺和诺德长效生长激素III期研究成功。5月12日，诺和诺德公布了REAL8篮子试验的数据，结果显示：每周给药一次的Sogroya在改善小于胎龄儿、努南综合征、特发性矮小症的青春期前儿童的年生长速率方面，与每日给药一次的生长激素Norditropin相当。此外，在患有努南综合征的儿童中，Sogroya较每日一次的生长激素具有优越性，同时在小于胎龄儿的儿童中，Sogroya较每日低剂量的生长激素也具有...

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市场速递1）翰宇药业与碳云智肽签署GLP-1R/GIPR/GCGR三重激动剂多肽创新药物联合开发协议5月12日，翰宇药业公告称，公司与碳云智肽就GLP-1R/GIPR/GCGR三重激动剂多肽创新药物签署联合开发协议，继续深化合作。双方将共同开发创新型多肽药物，应用于体重控制等代谢性疾病治疗领域。/ 02 / 资本信息1）中国医药拟3.02亿元收购金穗科技100%股权5月12日，中国医药公告称，拟以现金3.02亿元收购新兴集团所持金穗科技100%股权。金穗科技主营业务为电商运营服务，运营产品涵盖个人健康消费产品、大健康等多个品类，已与飞利浦、欧姆龙等国内外知名品牌建立合作。目前的核心业务为飞利浦个人健康消费等产品的品牌授权经销。/ 03 / 医药动态1）礼来Bimagrumab注射液获临床许可5月12日，据CDE官网，礼来Bimagrumab注射液获临床许可，拟开展治疗肥胖或超重合并至少一种体重相关合并症人群的体重管理的研究。2）百济神州BGB-16673片获临床许可5月12日，据CDE官网，百济神州BGB-16673片获临床许可，拟开展治疗慢性自发性荨麻疹的研究。3）荣昌生物RC278获得临床试验申请受理通知书5月12日，荣昌生物公告，注射用RC278的临床试验申请获CDE受理。RC278是公司自主研发的具有First-in-Class/Best-in-Class潜质的ADC分子，能特异识别一个新型肿瘤靶点，在临床前研究中展现出广谱抗肿瘤活性、良好的安全性和药代动力学特征。4）维迪西妥单抗治疗HER2表达的一线尿路上皮癌III期研究达到主要研究终点5月12日，荣昌生物宣布，维迪西妥单抗联合特瑞普利单抗，对比化疗治疗HER2表达的一线局部晚期或转移性尿路上皮癌的III期临床研究，在预先设定的独立数据监察委员会中期分析中显示强阳性结果，达到无进展生存期和总生存期的两项主要研究终点，研究结果具有统计学显著差异和重大临床获益。在主要亚组分析中，不论患者是否适合接受顺铂治疗以及不论HER2表达状态，维迪西妥单抗联合特瑞普利单抗相比化疗均显著改善PFS和OS。整体安全性良好，不良反应可控。5）默沙东新型抗菌药物锐可博在华上市5月12日，默沙东宣布，其新型碳青霉烯/酶抑制剂复合制剂锐可博®（注射用亚胺西瑞）已正式在中国境内上市，适用于治疗18岁及以上患者由敏感革兰阴性菌引起的多项感染。/ 04 / 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