创胜集团-B(06628.HK)：于AACR 2025上公布了基于新型人源化FGFR2b抗体的ADC(TST105)的最新临床前研究结果

格隆汇2025-04-30

格隆汇4月30日丨创胜集团-B(06628.HK)发布公告，公司于2025年美国癌症研究协会年会(AACR 2025)上公布了基于新型人源化FGFR2b抗体的ADC(TST105)的最新临床前研究结果。该ADC采用糖基转移酶介导的定点偶联技术，搭载新型拓扑异构酶I抑制剂作为有效载荷，在临床前胃癌和结直肠癌模型中，相比以MMAE为载荷的ADC，展现出显着增强的抗肿瘤活性。

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