章泽天自曝帕金森家族病史，这几类年轻人需提高警惕

新京报04-17

30岁的章泽天日前在社交平台自曝家族病史：“其实，我家里也有帕金森基因。我摄入过多咖啡因或睡眠不足时，大拇指已经开始会有点发抖了。”继世界帕金森日后，青年帕金森病再次进入人们的视野。“以前，很多帕金森病患者大多发生在40岁以后甚至更大年龄，且帕金森病大多被认为神经退行性病变。”首都医科大学三博脑科医院功能神经外科主任医师关宇光表示，这不意味着只有老年人才会患帕金森病，部分年轻人因为遗传或基因等相关...

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vigilant","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"89618":0.6,"09618":1,"JD":0.6},"content_text":"30岁的章泽天日前在社交平台自曝家族病史：“其实，我家里也有帕金森基因。我摄入过多咖啡因或睡眠不足时，大拇指已经开始会有点发抖了。”继世界帕金森日后，青年帕金森病再次进入人们的视野。“以前，很多帕金森病患者大多发生在40岁以后甚至更大年龄，且帕金森病大多被认为神经退行性病变。”首都医科大学三博脑科医院功能神经外科主任医师关宇光表示，这不意味着只有老年人才会患帕金森病，部分年轻人因为遗传或基因等相关问题，会在40岁前患帕金森病，这种帕金森病被称为早发型或青年型帕金森病。青年型帕金森病患者患遗传型的占比较普通型更大，且大多数青年型帕金森病患者的疾病进展较普通型帕金森病更快。关宇光介绍，除基因等遗传因素外，环境中的毒性物质如苯、农药除草剂等也可能导致青年人患上帕金森病。面对“青年帕金森病”，关宇光提醒以下几类年轻人群提高警惕。有帕金森病家族史人群：例如直系亲属或不太远的旁支亲属患有帕金森病，这其中，部分人群能够明确检查出基因异常，部分人群虽检测不出基因异常，但因为遗传易感，相较于其他人群，其患帕金森病的可能性也会更高。出现静止性震颤（抖）的人群：如果出现静止性震颤这种明显信号，应及时就医。出现运动迟缓的人群：经常感觉走路疲劳无力，出现肩、背、腰、腿等局部疼痛的人群，也应及时就医。“当然，手抖未必是帕金森。”在临床鉴别诊断上，关宇光指出，医生通过询问病史并配合实际检查进行诊断。实际检查包括基因检测；头部核磁排除脑血管病变、颅内肿瘤等情况；进行肌电图鉴别，了解抖动频率、肌群受累部位等；通过超声进行黑质检查；通过评分量表整体看患者的状态。此外，还可以进行左旋多巴胺冲击实验。关宇光表示，帕金森病的核心问题是多巴胺分泌减少导致的抖，如果通过补充一定量的多巴胺患者会有明显改善，也是诊断帕金森病的支持标准。尽管人们很难做到对帕金森病的完全预防，关宇光仍建议人们日常养成良好的睡眠习惯、均衡饮食、建立良好心态。“很多疾病的发生都与焦虑抑郁有关，如果出现轻微帕金森症状，人们首先要从心理进行克服，在疾病程度尚不严重时，可以通过行为和锻炼去对抗疾病，一旦明确诊断，则需要在医生的指导下进行早期用药，遵医嘱治疗。”关宇光表示，青年型帕金森病患者的治疗方案与普通帕金森病患者区别不大，早期大多是药物干预，晚期则考虑脑起搏器GPS手术治疗，未来，期待更多新治疗方式，如闭环脑机接口治疗方式、干细胞治疗、基因疗法等运用于帕金森病的治疗中。新京报记者 张兆慧校对 柳宝庆","kind":null,"is_publish_news":null,"is_publish_highlight":null,"is_publish_live":null,"is_publish_wemedia":null,"editions":null,"symbols":[],"gpt_button":1},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":false,"deviceId":"web-server-community-laohu8-v3","version":"4.22.4","shortVersion":"4.22.4","platform":"web","vendor":"web","appName":"laohu8","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2428397433"}