默沙东2.08亿美元收购一家初创公司

医药魔方04-09

近日，默沙东收购了初创公司Abceutics，这是一家从纽约州立大学布法罗分校（简称UB）研究员Joseph P. Balthasar博士的实验室分离出来的生物制药公司。这笔交易潜在对价高达2.08亿美元，其中包括候选药物进展的里程碑付款。Balthasar及其同事于2020年创办了Abceutics，该团队设计了“载荷结合选择性增强剂”（PBSEs）来结合、中和游离的载荷，以减少对健康细胞的影响...

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Balthasar博士的实验室分离出来的生物制药公司。这笔交易潜在对价高达2.08亿美元，其中包括候选药物进展的里程碑付款。Balthasar及其同事于2020年创办了Abceutics，该团队设计了“载荷结合选择性增强剂”（PBSEs）来结合、中和游离的载荷，以减少对健康细胞的影响，其与ADC联用，能够降低ADC药物的毒副作用，从而优化ADC疗法的选择性和功效。ADC药物对肿瘤治疗的重要性不言而喻，不仅填补了一些临床治疗空白，重塑了治疗标准，同时也不断实现跨肿瘤领域的临床突破，但如何更好地平衡疗效和安全性一直是开发ADC药物的挑战。2022年以来，默沙东先后引进科伦博泰、第一三共的ADC药物，大手笔进击ADC赛道。此番收购后，默沙东也将围绕ADC药物的安全性能和疗效作进一步优化。","kind":null,"is_publish_news":null,"is_publish_highlight":null,"is_publish_live":null,"is_publish_wemedia":null,"editions":null,"symbols":[],"gpt_button":1},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":false,"deviceId":"web-server-community-laohu8-v3","version":"4.22.4","shortVersion":"4.22.4","platform":"web","vendor":"web","appName":"laohu8","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2426860441"}