阿斯利康(AZN.US)靶向FRα的ADC在中国获批临床

智通财经网2023-11-07

智通财经APP获悉，11月6日，中国国家药监局药品审评中心(CDE)官网公示，阿斯利康(AZN.US)申报的1类新药AZD5335获得临床试验默示许可，拟开发治疗晚期实体瘤。公开资料显示，AZD5335是一种由叶酸受体α(FRα)靶向抗体与阿斯利康专有的拓扑异构酶1抑制剂(TOP1i)有效载荷连接而成的抗体偶联药物(ADC)，正在海外开展1/2期临床研究。根据ClinicalTrials官网，...

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