默沙东启动Kandlelit-007三期临床试验：评估口服KRAS G12C抑制剂Calderasib联合Keytruda Qlex™治疗晚期非小细胞肺癌

美股速递01-07

默沙东（Merck）近日宣布启动Kandlelit-007三期临床试验，旨在评估其研究性口服KRAS G12C抑制剂Calderasib（代号MK-1084）与Keytruda Qlex™（包含帕博利珠单抗及透明质酸酶阿尔法-PMPH）联合疗法，在特定晚期非小细胞肺癌（NSCLC）患者中的疗效与安全性。

该试验聚焦于携带KRAS G12C突变的晚期NSCLC患者群体，探索Calderasib与免疫疗法Keytruda Qlex™的协同作用。若研究取得积极结果，有望为这类难治性肺癌患者提供新的治疗选择。

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