Oncolytics Biotech Inc - Pelareorep联合疗法在二线KRAS突变MSS型结直肠癌中展现19.5个月中位缓解持续时间

美股速递05-04

Oncolytics Biotech Inc宣布，其核心候选药物pelareorep联合疗法在针对二线治疗KRAS突变、微卫星稳定（MSS）型转移性结直肠癌（mCRC）的临床试验中取得积极数据。研究结果显示，该联合治疗方案的中位缓解持续时间达到19.5个月，展现出持久的抗肿瘤活性。

这一数据凸显了pelareorep在难治性结直肠癌患者群体中的治疗潜力，特别是针对KRAS突变这一常见且治疗挑战较大的亚型。较长的缓解持续时间可能为患者带来更显著的临床获益，也为后续临床开发提供了有力支持。

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