BioAge宣布扩大口服NLRP3抑制剂BGE-102适应症范围，拟于2026年中启动针对糖尿病黄斑水肿患者的1b/2a期概念验证临床试验

美股速递01-20

BioAge Labs Inc.近日公布其口服NLRP3抑制剂BGE-102的适应症拓展计划。该企业拟于2026年中期启动一项针对糖尿病黄斑水肿患者的1b/2a期概念验证临床试验，旨在评估BGE-102在该疾病领域的治疗潜力。

此次适应症扩展标志着BioAge在炎症性疾病治疗领域的战略布局进一步深化。糖尿病黄斑水肿作为糖尿病常见的视网膜并发症，目前临床治疗选择仍存在局限性，BGE-102的介入有望为患者提供新的治疗方向。

临床试验将重点验证BGE-102通过抑制NLRP3炎症小体通路，在缓解视网膜炎症和血管渗漏方面的疗效。若试验结果达到预期，将为企业后续的产品管线拓展奠定重要基础。

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