Tvardi Therapeutics Inc 新一代STAT3抑制剂Tti-109一期临床健康受试者顶线数据预计2026年上半年公布

美股速递01-08

Tvardi Therapeutics Inc宣布，其新一代STAT3抑制剂Tti-109的一期临床试验取得重要进展。针对健康志愿者的顶线数据收集工作正按计划推进，预计将于2026年上半年完成。

该研究旨在评估Tti-109的安全性、耐受性及药代动力学特征。STAT3作为关键信号传导蛋白，在多种肿瘤生长中扮演核心角色。Tti-109通过精准抑制STAT3活性，为晚期癌症治疗提供了新思路。

目前临床试验进程符合预期时间表。若数据结果达到预设终点，将为后续针对实体瘤和血液恶性肿瘤的二期研究奠定基础。

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