Monte Rosa Therapeutics宣布Vav1靶向分子胶降解剂MRT-6160（DDY391）II期临床研究启动，达成里程碑节点

美股速递09-08 19:03

Monte Rosa Therapeutics今日宣布，其针对Vav1靶点的分子胶降解剂MRT-6160（亦称DDY391）已正式启动II期临床研究，此举标志着公司在该项目上达成了又一重要里程碑。

这一进展不仅彰显了公司在靶向蛋白降解领域的持续深耕，也为后续临床开发注入了新的动能。MRT-6160作为一款创新性的分子胶降解剂，旨在通过诱导Vav1蛋白的泛素化降解，从而精准调控相关信号通路，为特定疾病治疗提供全新策略。

随着II期研究的正式启动，Monte Rosa Therapeutics有望进一步积累该候选药物的临床数据，评估其在目标患者群体中的疗效与安全性。公司方面表示，将稳步推进这一研发管线，并期待在未来的医学大会上分享更多关键研究结果。

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